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Osteoprotegerin Antikörper

TNFRSF11B Reaktivität: Human WB, EIA Wirt: Maus Monoclonal OPG-01 unconjugated
Produktnummer ABIN114706
  • Target Alle Osteoprotegerin (TNFRSF11B) Antikörper anzeigen
    Osteoprotegerin (TNFRSF11B) (Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))
    Reaktivität
    • 61
    • 21
    • 18
    • 2
    • 2
    • 2
    • 2
    Human
    Wirt
    • 50
    • 12
    • 2
    • 1
    Maus
    Klonalität
    • 54
    • 11
    Monoklonal
    Konjugat
    • 43
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Osteoprotegerin Antikörper ist unkonjugiert
    Applikation
    • 49
    • 29
    • 26
    • 18
    • 11
    • 8
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    The antibody recognizes human Osteoprotegerin. Other species not tested.
    Aufreinigung
    Affinity chromatography on protein G
    Immunogen
    Recombinant human Osteoprotegerin (OPG Fc Chimera) produced in E. coli.
    Klon
    OPG-01
    Isotyp
    IgG1
    Top Product
    Discover our top product TNFRSF11B Primärantikörper
  • Applikationshinweise
    ELISA. Western Blot.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Rekonstitution
    Restore with 0.1 mL of deionized water. Let the pellet dissolve completely. Slight turbidity may occur after reconstitution, which does not affect activity of the antibody. In this case clarify the solution by centrifugation.
    Konzentration
    1.0 mg/mL
    Buffer
    0.05 M phosphate buffer, 0.1 M NaCl, pH 7.2
    Handhabung
    Avoid repeated freezing and thawing. Do Not Freeze working dilutions.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Stock solution or aliquots thereof can be kept frozen at -20 °C.
  • Target
    Osteoprotegerin (TNFRSF11B) (Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))
    Andere Bezeichnung
    Osteoprotegerin / TNFRSF11B (TNFRSF11B Produkte)
    Synonyme
    CD254 antikoerper, ODF antikoerper, OPGL antikoerper, OPTB2 antikoerper, RANKL antikoerper, TRANCE antikoerper, hRANKL2 antikoerper, sOdf antikoerper, OCIF antikoerper, OPG antikoerper, TR1 antikoerper, Opg antikoerper, ocif antikoerper, opg antikoerper, tr1 antikoerper, TNF superfamily member 11 antikoerper, TNF receptor superfamily member 11b antikoerper, tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) antikoerper, TNF receptor superfamily member 11B antikoerper, tumor necrosis factor receptor superfamily member 11b S homeolog antikoerper, tumor necrosis factor receptor superfamily, member 11b antikoerper, TNFSF11 antikoerper, TNFRSF11B antikoerper, Tnfrsf11b antikoerper, tnfrsf11b.S antikoerper
    Substanzklasse
    Chemical
    Hintergrund
    Osteoprotegerin (OPG) or osteoclastogenesis inhibitory factor (OCIF) is a secretory glycoprotein belonging to TNF receptor superfamily. OPG consists of 401 amino acid residues, it has a molecular weight of 60 kDa as a monomer and 120 kDa as a disulfide-linked dimer and is produced in different tissues, e.g. bone, skin, liver, stomach, intestine and lung. Osteoprotegerin inhibits the recruitment, proliferation and activation of osteoclasts. Osteoclast formation activity may be monitored principally by determination of concentration ratio of osteoprotegerin ligand (OPGL)/OPG. Alteration of this ratio may be the cause of bone loss in many imbalances in bone metabolism such as osteoporosis, osteopetrosis, hypercalcemia, metastatic osteolytic lesions and rheumatic bone degradation.Synonyms: OCIF, OPG, Osteoclastogenesis inhibitory factor, Tumor necrosis factor receptor superfamily member 11B
    Gen-ID
    4982
    NCBI Accession
    NP_002537
    UniProt
    O00300
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