AIF1 Antikörper (Allograft Inflammatory Factor 1) (Biotin)

Details for Product anti-AIF1 Antibody No. ABIN112010, Anbieter: Anmelden zum Anzeigen
Antigen
  • fa04b11
  • wu:fa04b11
  • AIF1
  • aif1
  • AIF-1
  • IBA1
  • IRT-1
  • IRT1
  • Bart1
  • iba1
  • mrf-1
  • AI607846
  • D17H6S50E
  • G1
  • Iba1
  • AIF
  • AIF1L
  • allograft inflammatory factor 1
  • allograft inflammatory factor 1-like
  • aif1
  • AIF1
  • Aif1
  • C9ORF58
Reaktivität
Human, Ratte (Rattus)
212
107
97
8
7
2
2
1
1
Wirt
Maus
142
56
36
2
1
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser AIF1 Antikörper ist konjugiert mit Biotin
22
22
11
5
5
4
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
184
123
106
67
28
27
19
13
11
10
7
4
2
2
2
2
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen Purified Human recombinant AIF-1 Epitope is not further characterized.
Klon 1022-5
Isotyp IgG2b
Spezifität Recognizes AIF-1. This antibody BM4114B reacts with activated Macrophages / Microglial cells.
Reinigung Affinity Chromatography.
Andere Bezeichnung AIF1 (AIF1 Antibody Abstract)
Hintergrund Allograft Inflammatory Factor-1 is a Ca2+-binding peptide produced by activated macrophages and microglial cells. It has been suggested that AIF-1 expression is associated with chronic inflammatory processes. AIF-1, like the Ca2+-binding peptides MRP8 and MRP14, is expressed by activated macrophages and might participate in a variety of pathogenic processes in the mammalian brain and in chronic transplant rejection. It has been shown to be expressed early and persistently in chronically rejecting cardiac allografts but not in cardiac syngrafts and host hearts. The recently described apoptosis-inducing factor AIF is not related to AIF-1.Synonyms: AIF-1, Allograft inflammatory factor 1, IBA1, Ionized Calcium-Binding Adapter Molecule 1, Protein G1
Gen-ID 199
NCBI Accession NP_001614
UniProt P55008
Forschungsgebiet Inflammation
Pathways Smooth Muscle Cell Migration
Applikationshinweise Immunohistochemistry on Paraffin Sections: 5 μg/mL (1/40). Pretreatment is not necessary. Suggested Positive Control: Human spleen. This antibody does not react on routinely processed Frozen Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar
Rekonstitution Restore by adding 0.5 mL distilled water.
Konzentration 0.2 mg/mL
Buffer PBS containing 5 mg/mL BSA as a stabilizer and 0.09 % Sodium Azide as a preservative.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung This product is photosensitive and should be protected from light
Lagerung 4 °C
Informationen zur Lagerung Store the antibody undiluted Prior to and following reconstitution at 2-8 °C. DO NOT FREEZE!
Allgemeine Veröffentlichungen Schluesener, Seid, Meyermann: "Effects of autoantigen and dexamethasone treatment on expression of endothelial-monocyte activating polypeptide II and allograft-inflammatory factor-1 by activated macrophages and microglial cells in lesions of experimental autoimmune encephalomyelitis, n" in: Acta neuropathologica, Vol. 97, Issue 2, pp. 119-26, 1999 (PubMed).

Schluesener, Seid, Kretzschmar, Meyermann: "Allograft-inflammatory factor-1 in rat experimental autoimmune encephalomyelitis, neuritis, and uveitis: expression by activated macrophages and microglial cells." in: Glia, Vol. 24, Issue 2, pp. 244-51, 1998 (PubMed).

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