CD56 Antikörper

Produktnummer ABIN111265

Produktdetails anti-CD56 Antikörper

Target: CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))

Reaktivität: Human, Primate

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD56 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Spezifität: The antibody reacts with a 180 kDa isoform of CD56 (NCAM) expressed in leukocytes. It has been suggested that the antibody MEM-188 could react with Rhesus Monkey lymphocytes. Reactivity with other NCAM isoforms has not been tested.

Kreuzreaktivität (Details): Species reactivity (tested):Human and non-Human Primates.

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: KG-1 Human acute myelogenous leukaemia cell line

Klon: MEM-188

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Western Blot. Flow Cytometry. Immunoprecipitation. Immunohistochemistry on Paraffin Sections: 1/50Pretreatment: Heat retrieval (microwave oven) in citrate buffer standard ABC visualization. Positive Tissue: Positive membrane-specific reaction in adjacent peripheral nerve Stainingof paraprostatic autonomic ganglion. Staining technique: Standard ABC technique (DAB+).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 with 15 mM Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CD56

Target: CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))

Andere Bezeichnung: CD56 (NCAM1 Produkte)

Synonyme: CD56 antikoerper, MSK39 antikoerper, NCAM antikoerper, fj56g09 antikoerper, ncam antikoerper, ncam1 antikoerper, wu:fj56g09 antikoerper, NCAM1 antikoerper, n-cam antikoerper, E-NCAM antikoerper, NCAM-1 antikoerper, Ncam antikoerper, Cd56 antikoerper, N-CAM antikoerper, N-CAM-1 antikoerper, NCAM-C antikoerper, NCAMC antikoerper, N-CAM-1-B antikoerper, NCAM-1-B antikoerper, ncam1-a antikoerper, ncam1-b antikoerper, neural cell adhesion molecule 1 antikoerper, neural cell adhesion molecule 1a antikoerper, neural cell adhesion molecule 1 S homeolog antikoerper, neural cell adhesion molecule 1 L homeolog antikoerper, NCAM1 antikoerper, ncam1a antikoerper, ncam1 antikoerper, LOC100085373 antikoerper, ncam1.S antikoerper, Ncam1 antikoerper, ncam1.L antikoerper

Hintergrund: CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of immunoglobulin family serving as adhesive molecule which is ubiquitously expressed in nervous system, usually as 120 kDa, 140 kDa or 180 kDa isoform, and it is also found on T cells and NK cells. Polysialic modification results in reduction of CD56-mediated cell adhesion and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumours and ovarian granulosa cell tumours.Synonyms: N-CAM-1, NCAM, NCAM-1, Neural cell adhesion molecule 1

Gen-ID: 4684

NCBI Accession: NP_000606

UniProt: P13591