PRSS1 Antikörper

Produktnummer ABIN7101954

Produktdetails anti-PRSS1 Antikörper

Target: PRSS1 (Protease, serine, 1 (Trypsin 1) (PRSS1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PRSS1 Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA)

Spezifität: Human pancreatic trypsin. Recognizes specifically pancreatic trypsin. Does not cross react with Pancreatic Chymotrypsin.

Aufreinigung: Protein G affinity chromatography.

Immunogen: Purified human pancreatic trypsin

Klon: 401

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: ELISA: May be used in immunoassays to detect and quantitate Pancreatic Trypsin.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL (OD 280 nm)

Buffer: PBS, pH 7.4 without preservatives.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.

Details zu PRSS1

Target: PRSS1 (Protease, serine, 1 (Trypsin 1) (PRSS1))

Andere Bezeichnung: Trypsin-1 / PRSS1 (PRSS1 Produkte)

Synonyme: TRP1 antikoerper, TRY1 antikoerper, TRY4 antikoerper, TRYP1 antikoerper, LOC397853 antikoerper, Trypsin antikoerper, wu:fb57g08 antikoerper, zgc:109701 antikoerper, Dvtry-1 antikoerper, dvir_GLEANR_6853 antikoerper, DvirGJ21500 antikoerper, GJ21500 antikoerper, Try1 antikoerper, PTRYI antikoerper, RATPTRYI antikoerper, Try-1 antikoerper, Trygn16 antikoerper, protease, serine 1 antikoerper, protease, serine 1 L homeolog antikoerper, trypsin-1 antikoerper, Trypsin-1 antikoerper, trypsin I antikoerper, protease, serine 1 (trypsin 1) antikoerper, protease, serine, 1 (trypsin 1) antikoerper, PRSS1 antikoerper, prss1.L antikoerper, prss1 antikoerper, CpipJ_CPIJ000708 antikoerper, CpipJ_CPIJ007079 antikoerper, CpipJ_CPIJ007080 antikoerper, CpipJ_CPIJ012156 antikoerper, CpipJ_CPIJ016225 antikoerper, CpipJ_CPIJ016619 antikoerper, CpipJ_CPIJ018339 antikoerper, Dvir\Try1 antikoerper, trp-i antikoerper, Prss1 antikoerper

Hintergrund: The human pancreas secretes three different isoforms of the inactive trypsinogen into the small intestine, namely cationic trypsinogen, anionic trypsinogen (the two major isoforms) and mesotrypsinogen (a minor isoform). In the small intestine, each isoform is cleaved by Enterokinase into its active form, Trypsin-1, Trypsin-2 and Trypsin-3, respectively. All trypsins are members of the serine protease trypsin family. The activated trypsins go on to activate other protease zymogens and play a role in the autoactivation of trypsinogens. This suggests an important role for trypsins in digestion. Mutations in the gene encoding Trypsin-1 that stimulate its activity are associated with autosomal dominant hereditary pancreatitis (HCP), also known as chronic pancreatitis (CP), a disease characterized by persistent, severe abdominal pain due to calcifications of the parenchyma, pancreatic stones, cysts and pancreatic head enlargement. Trypsin-3, also known as Trypsin-4, is expressed in the brain in addition to the pancreas.Synonyms: Beta-trypsin, Cationic trypsinogen, Serine protease 1, TRP1, TRY1, TRYP1, Trypsin I

Gen-ID: 5644

NCBI Accession: NP_002760

UniProt: P07477