Lipocalin 2 Antikörper

Produktnummer ABIN1108051

Produktdetails anti-Lipocalin 2 Antikörper

Target: Lipocalin 2 (LCN2)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Lipocalin 2 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Spezifität: The monoclonal antibody 697 reacts with Human neutrophil lipocalin (HNL), also known as Human nGAL (25 kDa).

Aufreinigung: Protein G Chromatography

Klon: 697

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.02 % Sodium Azide, 0.1 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C.

Details zu Lipocalin 2

Target: Lipocalin 2 (LCN2)

Andere Bezeichnung: Lipocalin-2 (LCN2 Produkte)

Synonyme: LCN2 antikoerper, 24p3 antikoerper, MSFI antikoerper, NGAL antikoerper, AW212229 antikoerper, Sip24 antikoerper, lipocalin 2 antikoerper, LCN2 antikoerper, Lcn2 antikoerper

Hintergrund: Lipocalins are a widespread family of small, robust proteins that typically transport or store biological compounds which are either of low solubility or are chemically sensitive, including vitamins, steroids, odorants and metabolic products. The members of this lipocalins share a high similarity in their tertiary structures in spite of a low degree in amino-acid sequence identity: three highly conserved sequence motifs form a funnel-like beta barrel which encloses a hydrophobic pocket for the internal ligand binding. The human neutrophil lipocalin (HNL) is produced by neutrophil leukocytes and stored in intracellular specific granules. Neutrophil lipocalin is covalently linked to gelatinase B (MMP-9) and proMMP is stored in three forms: the monomeric form (92 kDa), the homodimer (220 kDa) and a heterodimer (125 kDa). During inflammation and neoplastic transformation the human neutrophil lipocalin (HNL) is produced in neutrophils and in epithelial cells. Furthermore neutrophil lipocalin is a superior means to distinguish acute bacterial and viral infections as well as it enables the determination of the neutrophil activation level.Synonyms: 25 kDa alpha-2-microglobulin-related subunit of MMP-9, HNL, LCN2, NGAL, Neutrophil Gelatinase-associated Lipocalin, Oncogene 24p3, p25

Gen-ID: 3934

NCBI Accession: NP_005555

UniProt: P80188

Pathways: Cellular Response to Molecule of Bacterial Origin, Transition Metal Ion Homeostasis