Laminin gamma 1 Antikörper

Produktnummer ABIN1108021

Produktdetails anti-Laminin gamma 1 Antikörper

Target: Laminin gamma 1 (LAMC1) (Laminin, gamma 1 (LAMC1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Laminin gamma 1 Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Spezifität: The antibody recognizes the Mr 200,000 gamma-1-chain of Human reduced and Alkylated Laminin produced by various cultured cells, which produce Laminins complexed with it. The specificity of Mab BC17 has been confirmed by Immunoprecipitation and ELISA by using recombinant gamma-1- chain. The antibody only reacts with Human cells and tissues (further studies are going on).

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Ig Fraction

Immunogen: Pepsin-digested laminins from Human placenta. Hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.

Klon: BC17

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.09 % Sodium Azide, 1.0 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu Laminin gamma 1

Target: Laminin gamma 1 (LAMC1) (Laminin, gamma 1 (LAMC1))

Andere Bezeichnung: Laminin gamma 1 (LAMC1 Produkte)

Synonyme: lamb2 antikoerper, Lamb2 antikoerper, B2e antikoerper, sly antikoerper, LAMB2 antikoerper, putative laminin gamma-1 chain antikoerper, laminin subunit gamma 1 antikoerper, laminin, gamma 1 antikoerper, Smp_163810 antikoerper, lamc1 antikoerper, Lamc1 antikoerper, LAMC1 antikoerper

Hintergrund: Laminin, a major structural glycoprotein of the basement membranes, is an attachment and survival factor for epithelial cells and can also promote the growth of epithelial cells. Laminin plays an important role in both the structural organization of basement membranes and in the anchorage of cells. The monoclonal antibody, DG10 and BC17 against laminin chain ß1 and γ1, respectively can be widely applied in immunohistochemical studies as all basement membranes contain laminin trimers containing these chains. Antibodies to laminin chains are useful in basic biology studies as well as in pathological studies concerning, for instance, the integrity of the basement membranes in carcinomas.Synonyms: LAMB2, LAMC1, Laminin B2 chain, Laminin subunit gamma-1

Gen-ID: 3915

NCBI Accession: NP_002284

UniProt: P11047