CSNK2A2 Antikörper (AA 194-350)

Produktnummer ABIN1098114

Produktdetails anti-CSNK2A2 Antikörper

Target: CSNK2A2 (Casein Kinase 2, alpha Prime Polypeptide (CSNK2A2))

Bindungsspezifität: AA 194-350

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CSNK2A2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human CSNK2A2 (AA: 194-350) expressed in E. coli.

Klon: 1-00E-01

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-CSNK2A2 Antikörper (ABIN1098114)

Chemnitz, Pieper, Grüttner, Hauber: "Phosphorylation of the HuR ligand APRIL by casein kinase 2 regulates CD83 expression." in: European journal of immunology, Vol. 39, Issue 1, pp. 267-79, (2009) (PubMed).

Schäfer, Götz, Dudek, Hessenauer, Matti, Montenarh: "KIF5C: a new binding partner for protein kinase CK2 with a preference for the CK2alpha' subunit." in: Cellular and molecular life sciences : CMLS, Vol. 66, Issue 2, pp. 339-49, (2009) (PubMed).

Details zu CSNK2A2

Target: CSNK2A2 (Casein Kinase 2, alpha Prime Polypeptide (CSNK2A2))

Andere Bezeichnung: CSNK2A2 (CSNK2A2 Produkte)

Synonyme: CK2A2 antikoerper, CSNK2A1 antikoerper, 1110035J23Rik antikoerper, C77789 antikoerper, CK2 antikoerper, CSNK2A2 antikoerper, ck2a2 antikoerper, csnk2a1 antikoerper, wu:fi09h12 antikoerper, casein kinase 2 alpha 2 antikoerper, casein kinase 2, alpha prime polypeptide antikoerper, casein kinase 2 alpha 2 L homeolog antikoerper, casein kinase 2, alpha prime polypeptide a antikoerper, CSNK2A2 antikoerper, Csnk2a2 antikoerper, csnk2a2.L antikoerper, csnk2a2 antikoerper, csnk2a2a antikoerper

Hintergrund:

Description: Casein kinase II (CK2) is a constitutively active, ubiquitously expressed serine/threonine protein kinase that is thought to have a regulatory function in cell proliferation, cell differentiation and apoptosis. CK2 functions as a tetrameric complex consisting of two regulatory beta-subunits and two catalytic units (alpha and alpha') in a homomeric or heteromeric conformation. Whilst the alpha- and alpha'-subunits are catalytically identical, proteins that regulate CK2, such as cdc2 and Hsp90, preferentially bind to the alpha and not the alpha'-subunit. CK2 can phosphorylate a number of key intracellular signaling proteins implicated in tumor suppression (p53 and PTEN) and tumorigenesis (myc, jun, NF-kappaB). CK2 is also thought to influence Wnt signaling via beta-catenin phosphorylation and the PI 3-K signaling pathway via the phosphorylation of Akt.

Aliases: CK2A2, CSNK2A1, FLJ43934

Molekulargewicht: 41.2 kDa

Gen-ID: 1459

HGNC: 1459

Pathways: SARS-CoV-2 Protein Interaktom