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IL-32 alpha Antikörper (Biotin)

IL32A Reaktivität: Human ELISA, WB Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1043804
  • Target Alle IL-32 alpha (IL32A) Antikörper anzeigen
    IL-32 alpha (IL32A) (Interleukin 32 alpha (IL32A))
    Reaktivität
    Human
    Wirt
    • 4
    • 1
    Kaninchen
    Klonalität
    • 4
    • 1
    Polyklonal
    Konjugat
    • 2
    • 2
    • 1
    Dieser IL-32 alpha Antikörper ist konjugiert mit Biotin
    Applikation
    • 4
    • 4
    • 3
    • 1
    • 1
    ELISA, Western Blotting (WB)
    Spezifität
    This purified antibody has been heated to 56°C for 30 minutes. In ELISA and other immunoreactive assays, this antibody will recognize both native and recombinant human IL-32A in cell supernatants and certain body fluids. A control of similarly diluted normal rabbit IgG is recommended.
    Produktmerkmale
    IL-32A (also known as Natural killer cells protein 4, Tumor necrosis factor alpha-inducing factor, IL32alpha, Interleukin-32 and IL-32 isoform 4) is a member of the cytokine family. IL-32a is a secreted protein selectively expressed in lymphocytes and plays a role in innate and adaptive immune responses. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha and IL-8. It induces typical cytokine pathways of NF-kB and p38 MAPK. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
    Aufreinigung
    purified
    Immunogen
    This purified antibody was prepared from whole rabbit serum produced by repeated immunizations with full length recombinant human IL-32A protein.
    Immunogen Type: RecombinantProtein
    Isotyp
    IgG
  • Applikationshinweise
    This purified antibody has been tested for use in ELISA and western blotting. By western blot a band approximately 15 kDa in size corresponding to native human IL-32α protein is expected in the appropriate cell lysate or extract. Specific conditions for reactivity should be optimized by the end user.
    Kommentare

    Gene Name: IL32

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitution Buffer: Restore with deionized water (or equivalent), Reconstitution Volume: 100 µL
    Konzentration
    1.0 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
    Haltbarkeit
    12 months
  • Nishida, Andoh, Inatomi, Fujiyama: "Interleukin-32 expression in the pancreas." in: The Journal of biological chemistry, Vol. 284, Issue 26, pp. 17868-76, (2009) (PubMed).

  • Target
    IL-32 alpha (IL32A) (Interleukin 32 alpha (IL32A))
    Andere Bezeichnung
    IL-32A (IL32A Produkte)
    Synonyme
    IL-32alpha antikoerper, IL-32beta antikoerper, IL-32delta antikoerper, IL-32gamma antikoerper, NK4 antikoerper, TAIF antikoerper, TAIFa antikoerper, TAIFb antikoerper, TAIFc antikoerper, TAIFd antikoerper, interleukin 32 antikoerper, IL32 antikoerper
    Hintergrund
    IL-32A (also known as Natural killer cells protein 4, Tumor necrosis factor alpha-inducing factor, IL32α, Interleukin-32 and IL-32 isoform 4) is a member of the cytokine family. IL-32a is a secreted protein selectively expressed in lymphocytes and plays a role in innate and adaptive immune responses. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFα and IL-8. It induces typical cytokine pathways of NF-kB and p38 MAPK. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
    Synonyms: IL-32A, Natural killer cells protein 4, Tumor necrosis factor alpha-inducing factor, IL32α, Interleukin-32 and IL-32 isoform 4.
    Gen-ID
    9235, 61658634
    UniProt
    P24001
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