anti-Pferd Ubiquitin-Conjugating Enzyme E2D 3 Antikörper für Western Blotting

Recommended Ubiquitin-Conjugating Enzyme E2D 3 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3) Antikörper
  • UBE2D3P
  • Xubc4
  • e2(17)kb3
  • ubc4/5
  • ubch5c
  • ube2d3.1
  • E2(17)KB3
  • UBC4/5
  • UBCH5C
  • eff
  • fb36f02
  • wu:fb36f02
  • zgc:56340
  • ube2d2
  • xubc4
  • 1100001F19Rik
  • 9430029A22Rik
  • AA414951
  • ubiquitin conjugating enzyme E2 D3
  • ubiquitin-conjugating enzyme E2D 3
  • ubiquitin conjugating enzyme E2 D3 L homeolog
  • UBE2D3
  • LOC100223566
  • ube2d3
  • ube2d3.L
  • Ube2d3
Epitop
N-Term
13
10
9
8
8
2
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Yeast, Zebrafisch
53
9
9
1
1
1
1
1
1
1
Wirt
Kaninchen
40
13
Klonalität
Polyklonal
Konjugat
Unkonjugiert
4
4
4
3
3
3
Applikation
Western Blotting (WB)
47
34
7
1
1
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Request

Produkt kostenlos erhalten?

Für Ihre Validierungsdaten erstatten wir Ihnen den vollen Kaufpreis. Ich möchte dieses Produkt validieren

Mehr erfahren

Bilder

Produktnummer ABIN2775674
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN463336 WB Rabbit IgG N-Term Anmelden zum Anzeigen Polyclonal

General

Antigen Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3) Antikörper
Epitop N-Term
(13), (10), (9), (8), (8), (2), (1)
Reaktivität Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Yeast, Zebrafisch
(53), (9), (9), (1), (1), (1), (1), (1), (1), (1)
Wirt Kaninchen
(40), (13)
Klonalität
Polyklonal
Konjugat Unkonjugiert
(4), (4), (4), (3), (3), (3)
Applikation Western Blotting (WB)
(47), (34), (7), (1), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Referenzen Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN985813.
Sequenz MALKRINKEL SDLARDPPAQ CSAGPVGDDM FHWQATIMGP NDSPYQGGVF
Homologie Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%, Yeast: 92%, Zebrafish: 92%
Produktmerkmale This is a rabbit polyclonal antibody against UBE2D3. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human UBE2D3

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Referenzen Bilder zurück nach oben
Antigen
Andere Bezeichnung UBE2D3 (UBE2D3 Antibody Abstract)
Hintergrund The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D3 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Multiple spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.
Alias Symbols: E2(17)KB3, MGC43926, MGC5416, UBC4/5, UBCH5C
Protein Interaction Partner: NHLRC1, DTX2, TRIM63, RNF146, RNF26, RBX1, UBC, RNF5, RNF2, NEDD4, MID1, STUB1, TRIM39, OTUB1, MDM2, RNF111, TRIM33, PRPF19, RNF115, TRIM58, BTRC, MARCH7, NFKBIA, ARIH1, FBXW11, UBE2D3, PARK2, BRCA1, BARD1, UBE3A, MSL1, UBA1, CBLC, SMURF1, RNF130, UBA6, M
Protein Size: 147
Molekulargewicht 17 kDa
Gen-ID 7323
NCBI Accession NM_003340, NP_003331
UniProt P61077
Pathways Activation of Innate immune Response, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Referenzen Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 147 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Referenzen Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen

Produktdetails Antigendetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Hattori, Zhang, Jia, Subramanian, Jo, Loison, Newburger, Luo: "RNAi screen identifies UBE2D3 as a mediator of all-trans retinoic acid-induced cell growth arrest in human acute promyelocytic NB4 cells." in: Blood, Vol. 110, Issue 2, pp. 640-50, 2007

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung Referenzen zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3) (N-Term) antibody (ABIN2775674) WB Suggested Anti-UBE2D3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: