Chromosome 6 Open Reading Frame 150 Proteine (C6orf150)

Auf www.antikoerper-online.de finden Sie aktuell 5 Chromosome 6 Open Reading Frame 150 (C6orf150) Proteine von 4 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Chromosome 6 Open Reading Frame 150 Antikörper (41) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 50 Chromosome 6 Open Reading Frame 150 Produkte verfügbar.
Synonyme:
C6orf150, cGAS, h-cGAS
alle Proteine anzeigen Gen GeneID UniProt
C6orf150 115004 Q8N884
C6orf150    

Chromosome 6 Open Reading Frame 150 Proteine (C6orf150) nach Spezies

Weitere Proteine zu Chromosome 6 Open Reading Frame 150 Interaktionspartnern

Human Chromosome 6 Open Reading Frame 150 (C6orf150) Interaktionspartner

  1. Type I IFN is detrimental to the host, and dysregulation of iron homeostasis genes may explain lower bacteria survival in cGAS(-/-) and TLR4 (zeige TLR4 Proteine)(-/-) cells.

  2. the current study demonstrated that the DNA sensor cGAS is dynamically modified by SUMO

  3. while IFI16 (zeige IFI16 Proteine) induces cytokines, only cGAS activates STING/TBK-1 (zeige TBK1 Proteine)/IRF3 (zeige IRF3 Proteine) and apoptotic responses upon herpes simplex virus 1 and human cytomegalovirus infections; findings show that IFI16 (zeige IFI16 Proteine), not cGAS or PML (zeige PML Proteine), represses HSV-1 gene expression, reducing virus

  4. cGAs recognizes bacterial/viral DNA, and is a strong activator of STING that can further activate IRF3 (zeige IRF3 Proteine) and subsequent type I interferon (zeige IFNA Proteine) production. (Review)

  5. Data suggest that the N terminus enhanced the activity of core-cyclic GMP (zeige NT5C2 Proteine)-AMP (zeige APRT Proteine) synthase (cGAS) by facilitating formation of a monomeric complex of cGAS and DNA.

  6. Primary human endothelial cells mount robust type I interferon (zeige IFNA Proteine) responses to human cytomegalovirus that are dependent upon cyclic GMP (zeige NT5C2 Proteine)-AMP (zeige APRT Proteine) synthase (cGAS), STING, and interferon regulatory factor 3 (IRF3 (zeige IRF3 Proteine)) signaling.

  7. cGAS and STING are intracellular sensors that activate the interferon (zeige IFNA Proteine) pathway in response to virus infection. [review]

  8. cGAS silencing inhibited production of proinflammatory cytokines and matrix metalloproteinases (MMPs) as well as AKT (zeige AKT1 Proteine) and ERK (zeige EPHB2 Proteine) phosphorylation in TNFalpha (zeige TNF Proteine)-stimulated fibroblast-like synoviocytes

  9. A STING-dependent, cGAS-independent pathway important for full interferon (zeige IFNA Proteine) production and antiviral control of enveloped RNA viruses.

  10. By directly binding to cGAS, LANA, and particularly, a cytoplasmic isoform, inhibit the cGAS-STING-dependent phosphorylation of TBK1 (zeige TBK1 Proteine) and IRF3 (zeige IRF3 Proteine) and thereby antagonize the cGAS-mediated restriction of KSHV lytic replication.

Chromosome 6 Open Reading Frame 150 (C6orf150) Protein Überblick

Protein Überblick

Exhibits broad antiviral activity, most probably causing an early viral translation block.

Alternative names and synonyms associated with Chromosome 6 Open Reading Frame 150 (C6orf150)

  • chromosome 6 open reading frame 150 (C6orf150)
  • Mab-21 domain containing 1 (MB21D1)
  • C6orf150 Protein
  • cGAS Protein
  • h-cGAS Protein

Bezeichner auf Proteinebene für C6orf150

chromosome 6 open reading frame 150 , cGAMP synthase , cyclic GMP-AMP synthase , mab-21 domain-containing protein 1 , protein MB21D1

GENE ID SPEZIES
421864 Gallus gallus
100137406 Papio anubis
115004 Homo sapiens
Ausgewählte Anbieter für Chromosome 6 Open Reading Frame 150 Proteine (C6orf150)
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