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Chromosome 6 Open Reading Frame 150 Proteine (C6orf150)

Bezeichnung:
Chromosome 6 Open Reading Frame 150 Proteine (C6orf150)
Auf www.antikoerper-online.de finden Sie aktuell 5 Chromosome 6 Open Reading Frame 150 (C6orf150) Proteine von 4 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Chromosome 6 Open Reading Frame 150 Antikörper (37) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 46 Chromosome 6 Open Reading Frame 150 Produkte verfügbar.
Synonyme:
C6orf150, cGAS, h-cGAS
alle Proteine anzeigen Gen GeneID UniProt
C6orf150 115004 Q8N884
C6orf150    

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Weitere Proteine zu Chromosome 6 Open Reading Frame 150 Interaktionspartnern

Human Chromosome 6 Open Reading Frame 150 (C6orf150) Interaktionspartner

  1. the current study demonstrated that the DNA sensor cGAS is dynamically modified by SUMO

  2. while IFI16 (zeige IFI16 Proteine) induces cytokines, only cGAS activates STING/TBK-1 (zeige TBK1 Proteine)/IRF3 (zeige IRF3 Proteine) and apoptotic responses upon herpes simplex virus 1 and human cytomegalovirus infections; findings show that IFI16 (zeige IFI16 Proteine), not cGAS or PML (zeige PML Proteine), represses HSV-1 gene expression, reducing virus

  3. cGAs recognizes bacterial/viral DNA, and is a strong activator of STING that can further activate IRF3 (zeige IRF3 Proteine) and subsequent type I interferon (zeige IFNA Proteine) production. (Review)

  4. Data suggest that the N terminus enhanced the activity of core-cyclic GMP (zeige NT5C2 Proteine)-AMP (zeige APRT Proteine) synthase (cGAS) by facilitating formation of a monomeric complex of cGAS and DNA.

  5. Primary human endothelial cells mount robust type I interferon (zeige IFNA Proteine) responses to human cytomegalovirus that are dependent upon cyclic GMP (zeige NT5C2 Proteine)-AMP (zeige APRT Proteine) synthase (cGAS), STING, and interferon regulatory factor 3 (IRF3 (zeige IRF3 Proteine)) signaling.

  6. cGAS and STING are intracellular sensors that activate the interferon (zeige IFNA Proteine) pathway in response to virus infection. [review]

  7. cGAS silencing inhibited production of proinflammatory cytokines and matrix metalloproteinases (MMPs) as well as AKT (zeige AKT1 Proteine) and ERK (zeige EPHB2 Proteine) phosphorylation in TNFalpha (zeige TNF Proteine)-stimulated fibroblast-like synoviocytes

  8. A STING-dependent, cGAS-independent pathway important for full interferon (zeige IFNA Proteine) production and antiviral control of enveloped RNA viruses.

  9. By directly binding to cGAS, LANA, and particularly, a cytoplasmic isoform, inhibit the cGAS-STING-dependent phosphorylation of TBK1 (zeige TBK1 Proteine) and IRF3 (zeige IRF3 Proteine) and thereby antagonize the cGAS-mediated restriction of KSHV lytic replication.

  10. TRIM21 (zeige TRIM21 Proteine)-induced exposure of the viral genome promotes sensing of DNA and RNA viruses by cGAS and RIG-I (zeige DDX58 Proteine)

Chromosome 6 Open Reading Frame 150 (C6orf150) Protein Überblick

Protein Überblick

Exhibits broad antiviral activity, most probably causing an early viral translation block.

Alternative names and synonyms associated with Chromosome 6 Open Reading Frame 150 (C6orf150)

  • chromosome 6 open reading frame 150 (C6orf150)
  • Mab-21 domain containing 1 (MB21D1)
  • C6orf150 Protein
  • cGAS Protein
  • h-cGAS Protein

Bezeichner auf Proteinebene für C6orf150

chromosome 6 open reading frame 150 , cGAMP synthase , cyclic GMP-AMP synthase , mab-21 domain-containing protein 1 , protein MB21D1

GENE ID SPEZIES
421864 Gallus gallus
100137406 Papio anubis
115004 Homo sapiens
Ausgewählte Anbieter für Chromosome 6 Open Reading Frame 150 Proteine (C6orf150)
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