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Human Angiotensin II Type 2 Receptor ELISA Kit für Sandwich ELISA - ABIN417009
Clancy, Koblar, Golledge: Involvement of Angiotensin II Type 1 and 2 Receptors in Gelatinase Regulation in Human Carotid Atheroma in vitro. in Journal of atherosclerosis and thrombosis 2016
loss of AT2 R is associated with podocyte loss/dysfunction and is mediated, at least in part, via augmented ectopic hedgehog interacting protein (zeige HHIP ELISA Kits) expression in podocytes
In this genomewide association study, we found that variants at the EBF1 (zeige EBF1 ELISA Kits), EEFSEC, AGTR2, WNT4 (zeige WNT4 ELISA Kits), ADCY5 (zeige ADCY5 ELISA Kits), and RAP2C (zeige RAP2C ELISA Kits) loci were associated with gestational duration and variants at the EBF1 (zeige EBF1 ELISA Kits), EEFSEC, and AGTR2 loci with preterm birth.
crystal structures of human AT2R bound to an AT2R-selective ligand and to an AT1R (zeige AGTR1 ELISA Kits)/AT2R dual ligand, capturing the receptor in an active-like conformation
Suggest a gender-specific association between the AT2R -1332 A/G polymorphism and the occurrence of carotid plaque and the history of cerebrovascular insult in advanced carotid atherosclerosis.
peripheral and central arterial pressures and pulse wave augmentation indexes (AIx(P), AIx(C1), AIx(C2)), pulse wave velocity (PWV), daily urinary sodium excretion were measured and did genetic studies of AGTR1 (zeige AGTR1 ELISA Kits) A1166C and AGTR2 G1675A polymorphisms.
Significant overrepresentation of AT2R-1332 AA genotype in female multiple sclerosis patients was found, compared to female controls.
These data suggest that AT2R inhibits ligand-induced AT1R signaling through the PKC-dependent pathway.
Ang II (zeige AGT ELISA Kits)-induced upregulation of ATF3 (zeige ATF3 ELISA Kits) and SUMO1 (zeige SUMO1 ELISA Kits) in vitro and in vivo was blocked by Ang II (zeige AGT ELISA Kits) type I receptor antagonist olmesartan. Moreover, Ang II (zeige AGT ELISA Kits) induced ATF3 (zeige ATF3 ELISA Kits) SUMOylation at lysine 42, which is SUMO1 (zeige SUMO1 ELISA Kits) dependent
The A1166C polymorphism of AT1R (zeige AGTR1 ELISA Kits), A1675G and C3123A polymorphisms of AT2R were analyzed. The A1675G polymorphism of AT2R might be associated with preeclampsia
Ten tagging single nucleotide polymorphisms on AGTR1 (zeige AGTR1 ELISA Kits)/AGTR2 were genotyped for all subjects with primary aldosteronism and controls.
AT2R-dependent interleukin-17 (zeige IL17A ELISA Kits) production by T lymphocyte is necessary for collateral artery growth.
Altered expression of AT1 and AT2 receptors with aging may induce mitochondrial dysfunction, the main risk factor for neurodegeneration.
AT2R inhibits adipogenic differentiation in mesenchymal stem cells. Moreover, this inhibitory effect is associated with Wnt10b (zeige WNT10B ELISA Kits)/beta-catenin (zeige CTNNB1 ELISA Kits) signaling.
These results suggest that nerve growth factor-mediated neurite outgrowth is suppressed by AT2 receptor signaling via the nitric oxide-cyclic GMP (zeige NT5C2 ELISA Kits)-PKG (zeige PRKG1 ELISA Kits) pathway.
AT2R expressing neurons make GABAergic synapses onto AVP (zeige AVP ELISA Kits) neurons that inhibit AVP (zeige AVP ELISA Kits) neuronal activity and suppress baseline systemic AVP (zeige AVP ELISA Kits) levels.
Further deletion/mutation analysis revealed that multiple transcription factor binding sites in the +286/+690 region within intron 2 coordinately regulate AT2R transcription. Importantly, +286/+690 enhancer activity was suppressed in CHF mouse skeletal muscle, suggesting that AT2R expression is suppressed in CHF via inhibition of AT2R intronic enhancer activity, leading to lowered muscle regeneration.
This study suggests that deletion of AT2R decreases the expression of the beneficial ACE2/Ang-(1-7)/MasR.
Hypercholesterolemia blunts the oxidative stress and inflammatory cell recruitment elicited by hypertension in venules through a mechanism that involves AT2 receptor activation.
These results suggest that in the absence of AT2R, wound healing rate is accelerated, but yielded worse skin quality.
Luminal ANG II is internalized as a complex with AT1R/AT2R heterodimers to target endoplasmic reticulum in LLC-PK1 cells, where it might trigger intracellular calcium responses.
AT1 (zeige AGTR1 ELISA Kits) and AT2 receptors heterodimerize and are involved in the angiotensin II effect on SERCA (zeige ATP2A3 ELISA Kits) in proximal kidney tubules.
AT2 receptors are positively coupled to the proliferative response of vascular smooth muscle cells to angiotensin II.
Glomerular eNOS (zeige NOS3 ELISA Kits) gene expression was studied during postnatal maturation and AT1 receptor (zeige AGTRAP ELISA Kits) inhibition.
Data suggest that AGTR2 (and angiotensin-converting enzyme (zeige ACE ELISA Kits)) mRNA levels are transiently up-regulated in ovarian theca cells during preovulatory period.
data suggest that G alpha(i3), Shc (zeige SHC1 ELISA Kits), Grb2 (zeige GRB2 ELISA Kits), Ras, and Raf-1 (zeige RAF1 ELISA Kits) link Src (zeige SRC ELISA Kits) to activation of MAPK (zeige MAPK1 ELISA Kits) and to the AT(2)-dependent increase in eNOS (zeige NOS3 ELISA Kits) expression in PAECs
Abundance of AGTR2 mRNA in granulosa cells was higher in healthy compared with atretic follicles, whereas in theca cells, it did not change
The protein encoded by this gene belongs to the G-protein coupled receptor 1 family, and functions as a receptor for angiotensin II. It is an intergral membrane protein that is highly expressed in fetus, but scantily in adult tissues, except brain, adrenal medulla, and atretic ovary. This receptor has been shown to mediate programmed cell death and this apoptotic function may play an important role in developmental biology and pathophysiology. Mutations in this gene are been associated with X-linked mental retardation.
angiotensin II type-2 receptor
, type-2 angiotensin II receptor
, AT2 receptor
, angiotensin II type 2 receptor
, angiotensin receptor 2
, angiotensin II receptor type 2
, angiotensin type II receptor
, Type-2 angiotensin II receptor
, angiotensin II subtype 2 receptor, AT2