anti-gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) Antikörper

GABRG2 encodes a gamma-aminobutyric acid (GABA) receptor. Zusätzlich bieten wir Ihnen GABRG2 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
GABRG2 29709 P18508
GABRG2 2566 P18507
GABRG2 14406 P22723
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Top anti-GABRG2 Antikörper auf antikoerper-online.de

Showing 10 out of 117 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-GABRG2 Antibody Titration: </b>1.25ug/ml<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Ziege Unkonjugiert EIA, WB AP20117PU-N GABRG2 antibody staining of Mouse Brain lysate at 2 µg/ml (RIPA buffer, 35 µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert IHC, WB Western Blot: GABA-A R gamma 2 Antibody [ABIN152532] - Rat hippocampal (Hipp) lysate showing specific immunolabeling of the ~46 kDa gamma2-subunit of GABA A Receptor. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$447.56
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Western Blot: GABA-A R gamma 2 Antibody [ABIN152497] - 10 ug of rat brain lysate showing immunolabeling of the ~45-47 kDa GABA - A R, g2-subunit. 0.05 mL Anmelden zum Anzeigen 7 bis 9 Tage
$408.19
Details
Rind (Kuh) Kaninchen Unkonjugiert WB Host: Rabbit Target Name: GABRG2 Sample Type: Esophagus Tumor lysates Antibody Dilution: 1.0ug/ml Rabbit Anti-GABRG2 Antibody Catalog Number: ARP36738_P050 Formalin Fixed Paraffin Embedded Tissue: Human Adult Brain, cerebellum  Observed Staining: Cytoplasm in hepatocytes Primary Antibody Concentration: 1:600 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 – 2.0 sec 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB GABRG2 antibody (Center) (ABIN654148) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Fledermaus Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$493.17
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Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti GABRG2/GABA A Receptor gamma 2 Polyclonal Antibody, Unconjugated (ABIN754003) at 1:200 followed by conjugation to the secondary antibody and DAB staining Lane 1: human colon carcinoma lysates Lane 2: mouse brain lysates probed with Anti GABRG2/GABA A Receptor gamma 2 Polyclonal Antibody, Unconjugated (ABIN754003) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted band 51kD. Observed band size: 51kD. 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$295.90
Details

GABRG2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-GABRG2 Antikörper

  1. Human Polyclonal GABRG2 Primary Antibody für IHC, WB - ABIN152532 : Joshi, Sun, Kapur: A mouse monoclonal antibody against the γ2 subunit of GABAA receptors. in Hybridoma (2005) 2011 (PubMed)
    Show all 8 Pubmed References

  2. Human Polyclonal GABRG2 Primary Antibody für ICC, IF - ABIN152497 : Borghese, Werner, Topf, Baron, Henderson, Boehm, Blednov, Saad, Dai, Pearce, Harris, Homanics, Harrison: An isoflurane- and alcohol-insensitive mutant GABA(A) receptor alpha(1) subunit with near-normal apparent affinity for GABA: characterization in heterologous systems and production of knockin mice. in The Journal of pharmacology and experimental therapeutics 2006 (PubMed)
    Show all 6 Pubmed References

  3. Rat (Rattus) Polyclonal GABRG2 Primary Antibody für WB - ABIN361439 : Gomez, Froemke, Burden: Synaptic plasticity and cognitive function are disrupted in the absence of Lrp4. in eLife 2014 (PubMed)
    Show all 9 Pubmed References

  4. Human Monoclonal GABRG2 Primary Antibody für ICC, IP - ABIN2690511 : Kerti-Szigeti, Nusser: Similar GABAA receptor subunit composition in somatic and axon initial segment synapses of hippocampal pyramidal cells. in eLife 2016 (PubMed)

Weitere Antikörper gegen GABRG2 Interaktionspartner

Human gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) Interaktionspartner

  1. This study identified a missense de novo mutation in the GABAA (zeige GABRg1 Antikörper) receptor gamma2 subunit, P302L, in a patient with Dravet syndrome. The mutation has a novel pathogenic mechanism to cause defects in the conductance and gating of GABAA (zeige GABRg1 Antikörper) receptors, which results in hyperexcitability and contributes to the pathogenesis of the genetic epilepsy Dravet syndrome.

  2. This study demonstrated that rescue of PTZ seizure threshold and thalamocortical oscillations in a Gabrg2+/Q390X KI mouse model of Dravet syndrome/GEFS+ by overexpression of wild-type gamma2HA subunits.

  3. Defects in GABRG2/GABAergic neurotransmission participate in the pathogenesis of genetic epilepsies including epileptic encephalopathies.

  4. This review suggest that the pathogenesis of GABRG2 mutations is likely to be due to a combination of reduction of channel function and disturbance of cellular homeostasis due to the presence of mutant protein.

  5. Nova1 (zeige NOVA1 Antikörper) interacts with GABAARgamma2 not only in the central nervous system but also in hepatocellular carcinoma. Nova1 (zeige NOVA1 Antikörper)'s potential mechanism as an oncogene (zeige RAB1A Antikörper) may due to its interaction with GABAA (zeige GABRg1 Antikörper) Rgamma2.

  6. Thus, the presence of active GABA-A receptors, associated with phenotype determination via Ca(2 (zeige CA2 Antikörper)+)-signalling was demonstrated in differentiating human DA neurons.

  7. common variants of GABRG2, RELN (zeige RELN Antikörper) and NRG3 (zeige NRG3 Antikörper) and the GABRG2-RELN (zeige RELN Antikörper)-PTCH1 (zeige PTCH1 Antikörper) interaction networks might confer altered susceptibility to Hirschsprung disease.

  8. GABRG2, in combination with GABRA4 (zeige GABRA4 Antikörper), is associated with autism spectrum disorder in an Argentine dataset.

  9. Deletion of the N-terminal extension and putative alpha-helix in heteromeric alpha1beta2gamma2 GABAA (zeige GABRg1 Antikörper) receptors in the gamma2 subunits reduced the number of functional receptors and incorporation into mature receptors.

  10. Mutant GABRG2 may be responsible for genetic epilepsy as well neurodegeneration.

Mouse (Murine) gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) Interaktionspartner

  1. GABAA (zeige GABRg1 Antikörper) receptor (GABAAR) and the Na(+)-K(+)-2Cl(-) cotransporter (zeige SLC12A1 Antikörper) (NKCC1 (zeige SLC12A2 Antikörper)), but not the K(+)-Cl(-) cotransporter (zeige SLC12A4 Antikörper) (KCC2 (zeige SLC12A5 Antikörper)), were expressed in the terminals of the CRH (zeige CRH Antikörper) neurons at the median eminence (ME). In contrast, CRH (zeige CRH Antikörper) neuronal somata were enriched with KCC2 (zeige SLC12A5 Antikörper) but not with NKCC1 (zeige SLC12A2 Antikörper).

  2. This study demonstrated that the reduced local input to fast-spiking interneurons in the somatosensory cortex in the GABAA (zeige GABRg1 Antikörper) gamma2 R43Q mouse model of absence epilepsy.

  3. Heterozygous Gabrg2(+/Q390X) KI mice are associated with a severe epileptic encephalopathy due to a dominant negative effect of the mutation, while heterozygous Gabrg2(+/-) KO mice are associated with mild absence epilepsy due to simple haploinsufficiency.

  4. This investigation demonstrates striking interfacial GABAA (zeige GABRg1 Antikörper) receptor subunit selectivity in the native milieu, suggesting that asymmetric occupancy of heteropentameric ion channels by alkylphenol-based anesthetics is sufficient to induce modulation of activity.

  5. Study shows that the down-regulation of the gamma2 subunit of postsynaptic GABAARs in NG2 (zeige Vcan Antikörper) cells that accompanies the postnatal switch from synaptic to extrasynaptic GABAergic transmission between interneurons and these cells in the barrel cortex

  6. Dendritic spine abnormalities of Gabrg2+/- mice suggest association of functional defects in glutamatergic transmission with the established anxious-depressive phenotype of these mice

  7. KIF21B (zeige KIF21B Antikörper) participates in the delivery of GABAAR transport vesicles into dendrites.

  8. The study demonstrates the molecular and functional diversity of the GABAAR system within the mouse colon providing a framework for developing GABAAR-based therapeutics in GI disorders.

  9. these findings suggest that gephyrin (zeige GPHN Antikörper) may be a key factor in BDNF (zeige BDNF Antikörper)-dependent GABAAR regulation in the amygdala.

  10. This study showed that oscillatory activity in thalamic circuits is under the control of inhibition that involves gamma2 subunit-independent GABA-ARs (zeige SLURP1 Antikörper)

GABRG2 Antigen-Profil

Protein Überblick

This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene.

Genbezeichner und Symbole assoziert mit GABRG2

  • gamma-aminobutyric acid type A receptor gamma2 subunit (GABRG2) Antikörper
  • gamma-aminobutyric acid (GABA) A receptor, gamma 2 (gabrg2) Antikörper
  • gamma-aminobutyric acid type A receptor gamma 2 subunit (Gabrg2) Antikörper
  • gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 (Gabrg2) Antikörper
  • CAE2 Antikörper
  • ECA2 Antikörper
  • GABAA-R Antikörper
  • Gabrg-2 Antikörper
  • gabrg1 Antikörper
  • gamma2 Antikörper
  • GEFSP3 Antikörper
  • si:ch211-145n14.1 Antikörper

Bezeichner auf Proteinebene für GABRG2

gamma-aminobutyric acid A receptor, gamma 1 , GABA(A) receptor subunit gamma-2 , gamma-aminobutyric acid receptor subunit gamma-2 , gamma-aminobutyric acid A receptor gamma 2 , gamma-aminobutyric acid (GABA) A receptor, gamma 2 , gamma-aminobutyric acid receptor subunit gamma-2-like , gamma-aminobutyric acid A receptor, gamma 2 , gamma-aminobutyric acid (GABA-A) receptor, subunit gamma 2 , gamma-aminobutyric acid A receptor, gamma 2 , GABA-A receptor gamma-2 subunit , GABA(A) receptor, gamma 2

GENE ID SPEZIES
100059571 Equus caballus
779514 Xenopus (Silurana) tropicalis
100174267 Pongo abelii
100286791 Felis catus
100405062 Callithrix jacchus
29709 Rattus norvegicus
553402 Danio rerio
396289 Gallus gallus
2566 Homo sapiens
489141 Canis lupus familiaris
282240 Bos taurus
100516405 Sus scrofa
14406 Mus musculus
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