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Transcription factor required for myelination of differentiated oligodendrocytes. Zusätzlich bieten wir Ihnen Zinc Finger Protein 24 Proteine (7) und Zinc Finger Protein 24 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal ZNF24 Primary Antibody für IHC - ABIN967276
Han, Zhang, Ye, Kan, Gu, He, Shi, Zhou, Fu, Mao, Chen, Yu, Chen: Molecular cloning of six novel Krüppel-like zinc finger genes from hematopoietic cells and identification of a novel transregulatory domain KRNB. in The Journal of biological chemistry 2000
Show all 4 Pubmed References
Cow (Bovine) Polyclonal ZNF24 Primary Antibody für IHC, WB - ABIN2777982
Lv, Zhang, Wang, Meng, Liang, Zhang: Zinc finger protein 191 deficiency attenuates vascular smooth muscle cell proliferation, migration, and intimal hyperplasia after endovascular arterial injury. in Journal of vascular surgery 2014
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Human Polyclonal ZNF24 Primary Antibody für ICC, IF - ABIN4367085
Lopez-Contreras, Ruppen, Nieto-Soler, Murga, Rodriguez-Acebes, Remeseiro, Rodrigo-Perez, Rojas, Mendez, Muñoz, Fernandez-Capetillo: A proteomic characterization of factors enriched at nascent DNA molecules. in Cell reports 2013
ZFP191 played an essential role in aggressive proliferation and migration of vascular smooth muscle cells, which in turn facilitated intimal hyperplasia.
The loss of Zfp191 may suppress systemic inflammation by reducing these cytokine levels during lipopolysaccharide-induced endotoxic shock.
this study demonstrates that ZFP191 is required for the myelinating function of differentiated oligodendrocytes.
These data show that Zfp191 is indispensable for early embryonic development and cell proliferation.
the DNA-binding domain of Zfp191 can specifically bind to the TCAT repeat motif, and there is a cooperative effect among the target DNA's multiple binding sites
Data confirm ZNF191 as an essential factor acting for the promotion of the cell cycle and thus maintenance in the progenitor stage.
miR (zeige MLXIP Antikörper)-940 promoted gastric cancer progression by directly downregulating ZNF24 expression.
In vivo, knockdown of ZNF24 specifically in microvascular endothelial cells led to significantly decreased formation of functional vascular networks.
results suggest that consecutive ZF1 (zeige PRMT1 Antikörper)-2 is critical for the regulation of ZNF24 nuclear localization and its transactivation function.
ZNF24 represses VEGF transcription through direct binding to an 11-bp fragment of the VEGF proximal promoter and that it functions as a negative regulator of tumor growth by inhibiting angiogenesis.
ZNF24 may be implicated in transcriptional regulation of genes associated with oncogenesis via interaction with H2A.Z (zeige H2AFZ Antikörper).
ZNF191 can directly bind to the CTNNB1 (zeige CTNNB1 Antikörper) promoter and activate the expression of beta-catenin (zeige CTNNB1 Antikörper) and its downstream target genes such as cyclin D1 (zeige CCND1 Antikörper) in hepatoma cell lines.
These data suggest that ZNF24 is involved in negative regulation of PDGFR-beta (zeige PDGFRB Antikörper) and may represent a novel repressor of PDGFR-beta (zeige PDGFRB Antikörper) transcription.
Overexpression and purification of single zinc finger peptides of ZNF191 were performed.
ZNF191 is a pleiotropic factor that has a role in hematopoiesis, brain development, and tumor growth.
Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically bind to the 5'-TCAT-3' DNA sequence. Has transcription repressor activity in vitro.
hypomyelinated CNS protein
, zinc finger ZF-12
, zinc finger protein 24
, zinc finger protein ZF-12
, lacks zinc finger domain
, retinoic acid suppression protein A
, zinc finger and SCAN domain-containing protein 3
, zinc finger protein 191
, zinc finger protein 24 (KOX 17)
, zinc finger protein KOX17