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anti-WW Domain Containing Transcription Regulator 1 (WWTR1) Antikörper

WWTR1 encodes a binding protein of the 14-3-3 family of proteins that regulate cell cycle progression, differentiation and apoptosis. Zusätzlich bieten wir Ihnen WWTR1 Proteine (5) und WWTR1 Kits (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
WWTR1 25937 Q9GZV5
WWTR1 97064 Q9EPK5
WWTR1 295062  
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Top anti-WWTR1 Antikörper auf antikoerper-online.de

Showing 10 out of 51 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-WWTR1 Antibody Titration: 0.2-1 ug/mlPositive Control: HepG2 cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert EIA, WB WWTR1 Antibody (C-term) western blot analysis in 293 cell line lysates (35 µg/lane). This demonstrates the WWTR1 antibody detected the WWTR1 protein (arrow). 0.4 mL Anmelden zum Anzeigen 8 bis 10 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert WB Western Blot: TAZ Antibody [ABIN153163] - Western blot analysis of TAZ in MDCK cells using ABIN153163 at 1:250 dilution. 0.1 mg Anmelden zum Anzeigen 2 bis 4 Tage
363,75 €
Details
Human Kaninchen Unkonjugiert ChIP, ICC, IF, IHC (p), IP, SimWes, WB Detection of ABIN258561 protein using ABIN258561 on HEK 293 cell lysate. Simple Western: TAZ/WWTR1 Antibody [ABIN2585619] - Simple Western lane view shows a specific band for TAZ in 0.5 mg/ml of HeLa lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system. 0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
426,25 €
Details
Human Kaninchen Unkonjugiert WB WWTR1 Antibody (C-term)  western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the WWTR1 antibody detected the WWTR1 protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Maus Unkonjugiert IHC, WB Immunohistochemical staining of paraffin-embedded Human breast tissue using anti-WWTR1 mouse monoclonal antibody. (ABIN2455017) HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY WWTR1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-WWTR1. 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
366,67 €
Details
Human Maus Unkonjugiert FACS, IF, WB HEK293T cells transfected with either RC204082 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-WWTR1 antibody (ABIN2454926), and then analyzed by flow cytometry. Anti-WWTR1 mouse monoclonal antibody (ABIN2454926) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY WWTR1 (RC204082). 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
366,67 €
Details
Human Maus Unkonjugiert FACS, IF, WB HEK293T cells transfected with either RC204082 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-WWTR1 antibody (ABIN2454960), and then analyzed by flow cytometry. Anti-WWTR1 mouse monoclonal antibody (ABIN2454960) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY WWTR1 (RC204082). 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
418,10 €
Details
Human Maus Unkonjugiert FACS, IF, WB 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
583,17 €
Details
Human Maus Unkonjugiert IHC (p), WB 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
583,17 €
Details

WWTR1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human , ,
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Mouse (Murine)
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Rat (Rattus)


Am meisten referenzierte anti-WWTR1 Antikörper

  1. Human Polyclonal WWTR1 Primary Antibody für WB - ABIN153163 : Chan, Lim, Guo, Ng, Lee, Hunziker, Zeng, Hong: A role for TAZ in migration, invasion, and tumorigenesis of breast cancer cells. in Cancer research 2008 (PubMed)
    Zeige alle 7 Referenzen für ABIN153163

  2. Human Polyclonal WWTR1 Primary Antibody für ChIP, ICC - ABIN258561 : Strakova, Reed, Ihnatovych: Human transcriptional coactivator with PDZ-binding motif (TAZ) is downregulated during decidualization. in Biology of reproduction 2010 (PubMed)
    Zeige alle 5 Referenzen für ABIN258561

  3. Human Polyclonal WWTR1 Primary Antibody für EIA, WB - ABIN955592 : Remue, Meerschaert, Oka, Boucherie, Vandekerckhove, Sudol, Gettemans: TAZ interacts with zonula occludens-1 and -2 proteins in a PDZ-1 dependent manner. in FEBS letters 2010 (PubMed)
    Zeige alle 5 Referenzen für ABIN955592

  4. Cow (Bovine) Polyclonal WWTR1 Primary Antibody für WB - ABIN2779708 : Hong, Hwang, McManus, Amsterdam, Tian, Kalmukova, Mueller, Benjamin, Spiegelman, Sharp, Hopkins, Yaffe: TAZ, a transcriptional modulator of mesenchymal stem cell differentiation. in Science (New York, N.Y.) 2005 (PubMed)

Weitere Antikörper gegen WWTR1 Interaktionspartner

Zebrafish WW Domain Containing Transcription Regulator 1 (WWTR1) Interaktionspartner

  1. Yap (zeige YAP1 Antikörper)/Taz (zeige TAZ Antikörper)-Tead activity is necessary and sufficient for optic vesicle progenitors to adopt retinal pigment epithelium identity in zebrafish.

  2. Taz (zeige TAZ Antikörper) is required in the anteroposterior patterning of the pronephric progenitor domain in the intermediate mesoderm, acting in part by regulating retinoic acid signaling in the pronephric progenitor field in the intermediate mesoderm.

  3. Taz (zeige TAZ Antikörper)-depleted larvae displayed patterning defects in ventral cranial vessels that correlate with lateral displacement of thyroid follicles

  4. When transcriptional coactivators Yap (zeige YAP1 Antikörper) and Taz (zeige TAZ Antikörper) were restricted from interacting with Tead transcription factors through expression of a dominant negative transgene, cardiac precursors failed to migrate completely to the midline.

  5. TAZ (zeige TAZ Antikörper) has a critical role in osteoblast differentiation in vivo

Human WW Domain Containing Transcription Regulator 1 (WWTR1) Interaktionspartner

  1. SCLC cell lines of the YAP (zeige YAP1 Antikörper)/TAZ (zeige TAZ Antikörper) subgroup had higher sensitivity to the widely used anticancer agent for SCLC, topotecan.

  2. The activity of the YAP (zeige YAP1 Antikörper)/TAZ (zeige TAZ Antikörper) transcriptional coactivators, was found to be regulated by metabolic pathways, such as aerobic glycolysis and mevalonate synthesis, and by the nutrient-sensing LKB1 (zeige STK11 Antikörper)-AMPK (zeige PRKAA1 Antikörper) and TSC (zeige SLC12A3 Antikörper)-mTOR (zeige FRAP1 Antikörper) pathways. (Review)

  3. Over expression of TAZ (zeige TAZ Antikörper) was associated with abnormal expression of beta-catenin (zeige CTNNB1 Antikörper), which is correlated with poor prognosis of patients with adenocarcinoma of the esophagogastric junction

  4. Our findings emphasize the tumorigenic role of TAZ (zeige TAZ Antikörper) and may serve as the basis for new treatment strategies.

  5. Immortalized fibroblasts conditionally expressing active YAP (zeige YAP1 Antikörper) or TAZ (zeige TAZ Antikörper) mutant proteins overcome soft matrix limitations on growth and promote fibrosis

  6. Results revealed that TAZ (zeige TAZ Antikörper) is a differentially expressed molecule in human hepatocellular carcinoma (HCC (zeige FAM126A Antikörper)) suggesting it as an important regulator, TAZ (zeige TAZ Antikörper) might be as a new diagnostic biomarker in HCC (zeige FAM126A Antikörper).

  7. Results show TAZ (zeige TAZ Antikörper) functioned as an oncogene (zeige RAB1A Antikörper) and promoted pancreatic cancer epithelial-mesenchymal transition and progression.

  8. this article summarizes the current understanding of the biological functions of YAP (zeige YAP1 Antikörper) and TAZ (zeige TAZ Antikörper), and how the regulation of these two proteins can be disrupted in cancer.[Review][

  9. TAZ (zeige TAZ Antikörper) inhibits temozolomide induced apoptosis via upregulation of MCL-1 (zeige MCL1 Antikörper) (myeloid cell leukemia 1) and high expression of TAZ (zeige TAZ Antikörper) predicts a poor prognosis for GBM patients

  10. TAZ (zeige TAZ Antikörper) and YAP (zeige YAP1 Antikörper) are differentially regulated by hypoxia in cancer cells

Mouse (Murine) WW Domain Containing Transcription Regulator 1 (WWTR1) Interaktionspartner

  1. Results found that sclerostin (zeige SOST Antikörper) enhances adipocyte differentiation in 3T3-L1 cells and reduced TAZ (zeige TAZ Antikörper)-responsive transcriptional activity and TAZ (zeige TAZ Antikörper)-responsive gene expression, indicating a role for TAZ (zeige TAZ Antikörper) as a regulator of adipogenesis by sclerostin (zeige SOST Antikörper).

  2. Expression of TAZ (zeige TAZ Antikörper) promotes embryonic neural stem cell maintenance by enhancing stemness of neural stem cells during mammalian brain development.

  3. Tead2 (zeige TEAD2 Antikörper) transcription factors are crucial regulators of the cellular distribution of Yap (zeige YAP1 Antikörper) and Taz (zeige TAZ Antikörper), and together they control the expression of genes critical for EMT (zeige ITK Antikörper) and metastasis.

  4. findings uncover important roles for Yap (zeige YAP1 Antikörper) and Taz (zeige TAZ Antikörper) in cranial neural crest diversification and development

  5. Study discovered that YAP (zeige YAP1 Antikörper)/TAZ (zeige TAZ Antikörper) are bona fide downstream effectors of the alternative Wnt (zeige WNT2 Antikörper) signaling pathway.

  6. Hippo signalling effectors, YAP (zeige YAP1 Antikörper) and TAZ (zeige TAZ Antikörper), promote both the proliferation of intestinal stem/progenitor cells and their differentiation into goblet cells.

  7. This study identifies a novel mechanism of TAZ (zeige TAZ Antikörper) regulation by YAP (zeige YAP1 Antikörper), which has significant implications for our understanding of Hippo pathway regulation, YAP (zeige YAP1 Antikörper)-isoform specific signaling, and the role of these proteins in cell proliferation, apoptosis, and tumorigenesis

  8. Disrupting Yap (zeige YAP1 Antikörper)/Taz (zeige TAZ Antikörper) activities enhances Ret (zeige RET Antikörper) pathway activity and contributes to pathogenesis of lower urinary tract defects

  9. Immortalized fibroblasts conditionally expressing active YAP (zeige YAP1 Antikörper) or TAZ (zeige TAZ Antikörper) mutant proteins overcome soft matrix limitations on growth and promote fibrosis

  10. YAP (zeige YAP1 Antikörper)/TAZ (zeige TAZ Antikörper) regulate transcriptional elongation from the enhancer elements by recruiting the Mediator complex and promoting phenotypes of overgrowth and tumorigenesis

WWTR1 Antigen-Profil

Protein Überblick

This gene encodes a binding protein of the 14-3-3 family of proteins that regulate cell cycle progression, differentiation and apoptosis. The encoded protein is a transcriptional co-activator that binds to the PPXY motif present on transcription factors. The gene product contains a WW domain and, in the C-terminus, a conserved PDZ-binding motif. This gene is distinct from the gene encoding tafazzin. Both genes share the gene symbol Taz. Multiple transcript variants encoding different isoforms have been described.

Genbezeichner und Symbole assoziert mit WWTR1

  • WW domain containing transcription regulator 1 (wwtr1) Antikörper
  • WW domain containing transcription regulator 1 (WWTR1) Antikörper
  • WW domain containing transcription regulator 1 (Wwtr1) Antikörper
  • 2310058J06Rik Antikörper
  • 2610021I22Rik Antikörper
  • C78399 Antikörper
  • Taz Antikörper
  • WWTR1 Antikörper

Bezeichner auf Proteinebene für WWTR1

WW domain containing transcription regulator 1 , WW domain-containing transcription regulator protein 1 , taz , WW domain-containing transcription regulator protein 1-like , transcriptional co-activator with PDZ-binding motif , transcriptional coactivator with PDZ-binding motif , transcriptional coactivator with PDZ binding motif , transcriptional co-activator with PDZ-binding motif (TA)Z , transcriptional co-activator with PDZ-binding motif (TAZ)

GENE ID SPEZIES
496155 Xenopus laevis
568008 Danio rerio
100050661 Equus caballus
100401831 Callithrix jacchus
100437619 Pongo abelii
100493170 Xenopus (Silurana) tropicalis
100522573 Sus scrofa
100592028 Nomascus leucogenys
25937 Homo sapiens
609743 Canis lupus familiaris
614786 Bos taurus
97064 Mus musculus
295062 Rattus norvegicus
Ausgewählte Anbieter für anti-WWTR1 (WWTR1) Antikörper
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