WBP2 N-terminal Like Proteine (WBP2NL)

WBP2NL is a sperm-specific WW domain-binding protein that promotes meiotic resumption and pronuclear development during oocyte fertilization (Wu et al., 2007 [PubMed 17289678]).[supplied by OMIM, Mar 2008].. Zusätzlich bieten wir Ihnen WBP2 N-terminal Like Antikörper (32) und WBP2 N-terminal Like Kits (6) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Ratte WBP2NL WBP2NL 688642  
WBP2NL 164684 Q6ICG8
Maus WBP2NL WBP2NL 74716 Q9D529
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Showing 4 out of 4 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,442.50
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage
$785.40
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$405.71
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Hefe Macaca fascicularis His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,656.50
Details

WBP2NL Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,

Weitere Proteine zu WBP2 N-terminal Like (WBP2NL) Interaktionspartnern

Xenopus laevis WBP2 N-terminal Like (WBP2NL) Interaktionspartner

  1. wbp2nl has an additional developmental role in regionalizing the embryonic ectoderm.

  2. Data provides evidence for the first time that sperm-anchored PAWP is a primary initiator of zygotic development.

Human WBP2 N-terminal Like (WBP2NL) Interaktionspartner

  1. High fertilization (56.06%) and pregnancy (41.7%) rates accomplished in this study following ICSI-AOA (zeige APTX Proteine) indicated that expression profiles of PLCzeta (zeige PLCz1 Proteine), PAWP, and TR-KIT were low in globozoospermic individuals

  2. In male infertility, the absence of PLCZ1 (zeige PLCz1 Proteine) alone is sufficient to prevent oocyte activation irrespective of the presence of PAWP.

  3. Conclude that human PAWP is neither sufficient nor necessary for the Ca(2 (zeige CA2 Proteine)+) oscillations that initiate mammalian oocyte activation at fertilization.

  4. WBP2NL might play roles as an anti-apoptotic factor or co-activator to promote breast cancer cell survival and proliferation.

  5. Data suggest that PAWP (WW domain-binding protein 2-like) from sperm (rather than PLCZ (zeige PLCz1 Proteine) [phospholipase C zeta (zeige PLCz1 Proteine)] from sperm) acts as the 'sperm factor' within the egg at fertilization and is involved in 'egg activation' and embryogenesis. [REVIEW]

  6. Demonstrate significant correlations between sperm PAWP levels and both fertilization rates and normal embryonic development after intracytoplasmic sperm injection.

Cow (Bovine) WBP2 N-terminal Like (WBP2NL) Interaktionspartner

  1. PAWP correlates with semen/fertility parameters used in the cattle artificial insemination industry, making PAWP a potential biomarker of bull fertility.

  2. PAWP is a sperm-specific WW domain-binding protein that promotes meiotic resumption and pronuclear development during fertilization

Mouse (Murine) WBP2 N-terminal Like (WBP2NL) Interaktionspartner

  1. PAWP does not play an essential role in mouse fertilization

  2. The data suggest that sperm-derived PAWP is not involved in triggering Ca(2 (zeige CA2 Proteine)+) oscillations at fertilization in mammalian oocytes.

  3. These results indicate that PAWP plays a role in spermatogenesis and germ cell development. Moreover, we suggest PAWP as one of the markers that could be looked in ESC studies as a confirmed testis-specific (zeige AIF1 Proteine) gene

  4. The postacrosomal assembly of sperm head protein, PAWP, is independent of acrosome formation and dependent on microtubular manchette transport

WBP2 N-terminal Like (WBP2NL) Protein Überblick

Protein Überblick

WBP2NL is a sperm-specific WW domain-binding protein that promotes meiotic resumption and pronuclear development during oocyte fertilization (Wu et al., 2007

Genbezeichner und Symbole assoziert mit WBP2 N-terminal Like Proteine (WBP2NL)

  • WBP2 N-terminal like (Wbp2nl)
  • WBP2 N-terminal like L homeolog (wbp2nl.L)
  • WBP2 N-terminal like (wbp2nl)
  • WBP2 N-terminal like (WBP2NL)
  • 4930521I23Rik Protein
  • PAWP Protein

Bezeichner auf Proteinebene für WBP2 N-terminal Like Proteine (WBP2NL)

WBP2 N-terminal like , WW domain-binding protein 2-like , postacrosomal sheath WW domain-binding protein , PAWP

GENE ID SPEZIES
688642 Rattus norvegicus
494729 Xenopus laevis
100135228 Xenopus (Silurana) tropicalis
100356404 Oryctolagus cuniculus
164684 Homo sapiens
100685691 Canis lupus familiaris
523070 Bos taurus
74716 Mus musculus
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