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VDAC3 encodes a voltage-dependent anion channel (VDAC), and belongs to the mitochondrial porin family. Zusätzlich bieten wir Ihnen und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 45 products:
Cow (Bovine) Polyclonal VDAC3 Primary Antibody für IHC, WB - ABIN2776182
Lefièvre, Chen, Conner, Scott, Publicover, Ford, Barratt: Human spermatozoa contain multiple targets for protein S-nitrosylation: an alternative mechanism of the modulation of sperm function by nitric oxide? in Proteomics 2007
Show all 4 Pubmed References
Human Polyclonal VDAC3 Primary Antibody für WB - ABIN4894329
Tanno, Kuno, Ishikawa, Miki, Kouzu, Yano, Murase, Tobisawa, Ogasawara, Horio, Miura: Translocation of glycogen synthase kinase-3β (GSK-3β), a trigger of permeability transition, is kinase activity-dependent and mediated by interaction with voltage-dependent anion channel 2 (VDAC2). in The Journal of biological chemistry 2014
This cohort study showed that the VDAC3 gene was down regulation between patients with idiopathic Parkinson disease and controls
The works available on VDAC cysteines support the notion that VDAC1 (zeige VDAC1 Antikörper), VDAC2 (zeige VDAC2 Antikörper), and VDAC3 proteins are paralogs with a similar pore-function and slightly different, but important, ancillary biological functions. (Review)
VDAC3 is able to modulate its pore size and current by exploiting the mobility of the N-terminal and forming, upon external stimuli, disulfide bridges with cysteine residues located on the barrel and exposed to the inter-membrane space.
channel gating of VDAC3 might be controlled by redox sensing under physiological conditions
These data suggest that an interaction between Mcl-1 (zeige MCL1 Antikörper) and VDAC promotes lung cancer cell migration by a mechanism that involves Ca(2 (zeige CA2 Antikörper)+)-dependent reactive oxygen species production.
observed electrophysiological properties of hVDAC3 are surprisingly different from the other isoforms and are discussed in relation to the proposed physiological role of the protein in mammalian cells
a VDAC3-Mps1 (zeige IDUA Antikörper) module at the centrosome promotes ciliary disassembly during cell cycle entry.
VDAC3 is present at the mother centriole and modulates centriole assembly by recruiting Mps1 (zeige IDUA Antikörper) to centrosomes.
VDAC 1 (zeige VDAC1 Antikörper), 2, and 3 recruit Parkin (zeige PARK2 Antikörper) to defective mitochondria to promote mitochondrial autophagy.
VDAC3 has a limited ability to support mitochondrial respiration and has no influence in the control of ROS (zeige ROS1 Antikörper) production.
VDAC2 (zeige VDAC2 Antikörper) and VDAC3 might have an alternative structural organization and different functions in outer dense fibers (zeige ODF1 Antikörper) than in mitochondria
Bcl-xL (zeige BCL2L1 Antikörper) interacts functionally with VDAC1 (zeige VDAC1 Antikörper) and -3 but not VDAC2 (zeige VDAC2 Antikörper).
(n VDAC3 deficient mice the defect is restricted to the heart and only to complex IV.
Vdacs are dispensable for both MPT and Bcl-2 (zeige BCL2 Antikörper) family member-driven cell death.
Bid (zeige BID Antikörper) catalyzes MAC formation in isolated mitochondria containing Bax (zeige BAX Antikörper) and/or Bak (zeige BAK1 Antikörper) with a time course of minutes and does not require VDAC1 (zeige VDAC1 Antikörper) or VDAC3.
This gene encodes a voltage-dependent anion channel (VDAC), and belongs to the mitochondrial porin family. VDACs are small, integral membrane proteins that traverse the outer mitochondrial membrane and conduct ATP and other small metabolites. They are known to bind several kinases of intermediary metabolism, thought to be involved in translocation of adenine nucleotides, and are hypothesized to form part of the mitochondrial permeability transition pore, which results in the release of cytochrome c at the onset of apoptotic cell death. Alternatively transcript variants encoding different isoforms have been described for this gene.
, voltage-dependent anion channel 3
, voltage-dependent anion channel 5, pseudogene
, voltage-dependent anion-selective channel protein 3
, voltage-dependent anion channel 1 pseudogene 5
, outer mitochondrial membrane protein porin 3
, channel protein VDAC3
, mitochondrial outer membrane protein
, mitochondrial voltage dependent anion channel 3