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VPS28 encodes a protein involved in endosomal sorting of cell surface receptors via a multivesicular body/late endosome pathway. Zusätzlich bieten wir Ihnen VPS28 Antikörper (40) und viele weitere Produktgruppen zu diesem Protein an.
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In such lacking dVps28, several processes that require the actin cytoskeleton are perturbed.
Deletions of VPS28 and VPS32 increase the susceptibility of C. albicans to cell wall disruption agents, echinocandin and azole antifungal agents.
CIIA attenuates neurotoxicity caused by OGD (zeige FGFR1 Proteine)/R through inhibiting ASK1 (zeige MAP3K5 Proteine)-dependent signaling events.
CIIA functions as a molecular switch for the GEF activity of SOS1, directing this activity toward Rac1.
USP8 (zeige USP8 Proteine), and the endosomal sorting protein, VPS28, are the negative regulators of NOD2-induced IL-8 (zeige IL8 Proteine) secretion.
CIIA functions as a negative modulator of the SOS1 (zeige SOS1 Proteine)-Ras signaling events initiated by peptide growth factors including EGF (zeige EGF Proteine).
Data show that gamma2-adaptin in MVB sorting specifically interacts with the ESCRT subunits Vps28 and CHMP2A (zeige CHMP2A Proteine).
EIAV Gag interacts with a cellular component of the VPS machinery, VPS28, to accomplish efficient particle release
Overall, we see no role for the ESCRT pathway in influenza virus budding and the significance of the M1-VPS28 interaction remains to be determined.
This gene encodes a protein involved in endosomal sorting of cell surface receptors via a multivesicular body/late endosome pathway. The encoded protein is one of the three subunits of the ESCRT-I complex (endosomal complexes required for transport) involved in the sorting of ubiquitinated proteins. The two other subunits of ESCRT-I are vesicular protein sorting 23, also known as tumor susceptibility gene 101 (TSG101), and vesicular protein sorting 37. Two alternative transcripts encoding different isoforms have been described. Additional alternative transcripts may exist but the proteins encoded by these transcripts have not been verified experimentally.
, vacuolar protein sorting 28
, vacuolar protein sorting 28 homolog (S. cerevisiae)
, vacuolar protein sorting 28 homolog
, vacuolar protein sorting-associated protein 28 homolog
, ESCRT I complex subunit Vps28 (predicted)
, hypothetical protein
, subunit of the ESCRT-I complex
, vacuolar protein sorting-associated protein
, vacuolar protein sorting-associated protein 28
, ESCRT-I complex subunit VPS28
, caspase-activated DNase inhibitor that interacts with ASK1
, yeast class E protein Vps28p homolog