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UPK3A encodes a member of the uroplakin family, a group of transmembrane proteins that form complexes on the apical surface of the bladder epithelium. Zusätzlich bieten wir Ihnen Uroplakin 3A Antikörper (47) und Uroplakin 3A Kits (9) und viele weitere Produktgruppen zu diesem Protein an.
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High expression level of preoperative serum Uroplakin III is associated with biologically aggressive bladder cancer.
High Uroplakin III expression is associated with bladder urothelial carcinoma from malignancy metastatic to the urinary bladder.
a strong association between UPIII and in the group with tumor recurrence
Loss of p63 (zeige RPE65 Proteine) expression is a prerequisite for uroplakin III expression in urothelial bladder cancer.
Our results indicate that de novo mutations in UPIIIA can be involved in defective early kidney development, but probably constitute only a rare cause of human renal hypodysplasia in a minor subset of individuals [UPIIIA].
uroplakin III and III-delta4 genes were significantly up-regulated only in patients with nonulcerative interstitial cystitis
Uroplakin III mRNA is up-regulated to a greater extent in vesicoureteral reflux than in control exfoliated urinary cells.
Uroplakin III plays a pivotal role in Eshcerichia coli UTI (zeige AMBP Proteine) pathogenesis.
studies suggest that bacteria-induced UPIIIa signaling is a critical mediator of bladder responses to insult by uropathogenic E. coli
U-CCs (zeige CCS Proteine) (Uroplakin3a expressing cells )proliferate and generate CCs (zeige CCS Proteine) and ciliated cells in uninjured airways long-term and, like v-CCs (zeige CCS Proteine), after Nap (zeige CTNNBL1 Proteine). U-CCs (zeige CCS Proteine) have a higher propensity to generate ciliated cells than non-U-CCs (zeige CCS Proteine)
A UPK3A peptide can induce a peptide-specific CD4 (zeige CD4 Proteine)+ T cell autoimmunity that mediates painful bladder dysfunction in mice.
The despites a lower level of expression, UPIIIa maintain its plaque association in urothelial preneoplastic lesions.
This gene encodes a member of the uroplakin family, a group of transmembrane proteins that form complexes on the apical surface of the bladder epithelium. Mutations in this gene may be associated with renal adysplasia. Alternatively spliced transcript variants have been described.
, uroplakin 3A
, proplakin IIIa
, uroplakin 3
, uroplakin IIIA
, uroplakin 3A L homeolog