UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 4 (GalNAc-T4) Proteine (GALNT4)

GALNT4 encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. Zusätzlich bieten wir Ihnen UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 4 (GalNAc-T4) Antikörper (41) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
GALNT4 8693 Q8N4A0
Ratte GALNT4 GALNT4 500826  
GALNT4 14426 O08832
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 50 bis 55 Tage
$6,041.49
Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
$4,244.78
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$405.71
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GALNT4 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
, ,
Mouse (Murine)
,

Weitere Proteine zu UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 4 (GalNAc-T4) (GALNT4) Interaktionspartnern

Mouse (Murine) UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 4 (GalNAc-T4) (GALNT4) Interaktionspartner

Human UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 4 (GalNAc-T4) (GALNT4) Interaktionspartner

  1. GALNT4 Expression Is Directly Regulated by miR (zeige MLXIP Proteine)-9.

  2. Intronic SNP in POC1B (zeige POC1B Proteine)/GALNT4 locus (rs11105306) was associated with NT-proBNP levels in patients with acute coronary syndrome (ACS (zeige PLA2G15 Proteine)). The POC1B (zeige POC1B Proteine)/GALNT4 SNP was not associated with higher risk of cardiovascular death.

  3. GALNT14 (zeige GALNT14 Proteine) may contribute to ovarian carcinogenesis through aberrant glycosylation of MUC13 (zeige MUC13 Proteine).

  4. GALNT4 identified as a risk gene for cardiovascular disease, whose effects may be on either platelet or endothelial function through modifications of PSGL1 (zeige SELPLG Proteine) or other important glycosylated proteins.

UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 4 (GalNAc-T4) (GALNT4) Protein Überblick

Protein Überblick

This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. In vitro, the encoded protein can complement other GalNAc-Ts in the complete O-glycosylation of the mucin-1 tandem repeat and can O-glycosylate the P-selectin glycoprotein ligand-1 molecule. The coding region of this gene is contained within a single exon. Fusion transcripts, which combine part of this gene with the 5' exons of the neighboring POC1B (POC1 centriolar protein homolog B) gene, also exist.

Genbezeichner und Symbole assoziert mit GALNT4

  • polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4)
  • polypeptide N-acetylgalactosaminyltransferase 4 L homeolog (galnt4.L)
  • polypeptide N-acetylgalactosaminyltransferase 4 (Galnt4)
  • AV011803 Protein
  • GALNAC-T4 Protein
  • GALNACT4 Protein

Bezeichner auf Proteinebene für GALNT4

UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 4 , polypeptide GalNAc transferase 4 , polypeptide N-acetylgalactosaminyltransferase 4 , pp-GaNTase 4 , protein-UDP acetylgalactosaminyltransferase 4 , polypeptide GalNAc transferase-T4 , galNAc-T4 , ppGaNTase-T4

GENE ID SPEZIES
8693 Homo sapiens
432105 Xenopus laevis
500826 Rattus norvegicus
100125265 Bos taurus
14426 Mus musculus
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