Tumor Protein P53 Binding Protein 2 (TP53BP2) ELISA Kits

TP53BP2 encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. Zusätzlich bieten wir Ihnen Tumor Protein P53 Binding Protein 2 Antikörper (71) und Tumor Protein P53 Binding Protein 2 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
TP53BP2 21981 Q62415
TP53BP2 7159 Q13625
Anti-Ratte TP53BP2 TP53BP2 305025  
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96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
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788,70 €
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Weitere ELISA Kits für Tumor Protein P53 Binding Protein 2 Interaktionspartner

Zebrafish Tumor Protein P53 Binding Protein 2 (TP53BP2) Interaktionspartner

  1. These findings uncover a novel role of Aspp2 in regulating vertebrate embryonic growth.

Mouse (Murine) Tumor Protein P53 Binding Protein 2 (TP53BP2) Interaktionspartner

  1. SPP2 dominates the biological outcome, thus switching from a Gal-1 supported growth-promoting setting to a senescence inducing and stemness suppressive program in cancer cells. Our results support Ras nanocluster as major integrators of tumour fate decision events.

  2. After genotoxic stress, Aspp1 (zeige PPP1R13B ELISA Kits) promotes hematopoietic stem cell (HSC (zeige FUT1 ELISA Kits)) cycling and induces p53 (zeige TP53 ELISA Kits)-dependent apoptosis in cells with persistent DNA damage foci. Aspp1 (zeige PPP1R13B ELISA Kits) also attenuates HSC (zeige FUT1 ELISA Kits) self-renewal and accumulation of DNA damage in p53 (zeige TP53 ELISA Kits) null HSCs.

  3. ASPP2 may participate in the lipid metabolism of non-alcoholic steatohepatitis and attenuate liver failure.

  4. ASPP2 prevents beta-catenin (zeige CTNNB1 ELISA Kits) from transactivating ZEB1 (zeige ZEB1 ELISA Kits) directly by forming an ASPP2-beta-catenin (zeige CTNNB1 ELISA Kits)-E-cadherin (zeige CDH1 ELISA Kits) ternary complex

  5. findings suggest that the identified STAT1 (zeige STAT1 ELISA Kits)/ASPP2 pathway may connect tumor suppression and cell polarity to neuroinflammation

  6. our studies demonstrate the role of Siah2 (zeige SIAH2 ELISA Kits) in regulation of tight junction integrity and cell polarity under hypoxia, through its regulation of ASPP2 stability.

  7. ASPP2 is a tumor suppressor that suppresses squamous cell carcinoma via inflammatory signaling through NF-kappaB (zeige NFKB1 ELISA Kits)-mediated repression of p63 (zeige CKAP4 ELISA Kits).

  8. Our study demonstrates a novel role for ASPP1 (zeige PPP1R13B ELISA Kits) and ASPP2 in the death of retinal ganglion cells.

  9. regulates epithelial cell polarity in cooperation with PAR-3 (zeige F2RL2 ELISA Kits) to form an active PAR (zeige AFG3L2 ELISA Kits) complex

  10. Consistent with its role in cell polarity, ASPP2 influences interkinetic nuclear migration and lamination during CNS development.

Human Tumor Protein P53 Binding Protein 2 (TP53BP2) Interaktionspartner

  1. Expression levels of TP53BP2, FBXO28 (zeige FBXO28 ELISA Kits), and FAM53A genes were associated with patient survival specifically in ER-positive, TP53 (zeige TP53 ELISA Kits)-mutated tumors.

  2. These data together implicated a critical impact of MiR (zeige MLXIP ELISA Kits)-205/ASPP2 on promoting epithelial-mesenchymal transition.

  3. ASPP2 is a key regulator of BECN1 (zeige BECN1 ELISA Kits)-dependent autophagy.

  4. ASPP2 suppresses invasion, peritoneal dissemination and TGF-beta1 (zeige TGFB1 ELISA Kits)-induced EMT (zeige ITK ELISA Kits) by inhibiting Smad7 (zeige SMAD7 ELISA Kits) degradation mediated by ITCH in gastric cancer cells.

  5. Our results suggest that Gal-1 and ASPP2 functionally compete in nanocluster for active Ras on the plasma membrane. ASPP2 dominates the biological outcome, thus switching from a Gal-1 supported growth-promoting setting to a senescence inducing and stemness suppressive program in cancer cells. Our results support Ras nanocluster as major integrators of tumour fate decision events.

  6. ASPP2 suppresses p53 (zeige TP53 ELISA Kits) target gene transactivation, promoter occupancy, and endogenous p53 (zeige TP53 ELISA Kits) target gene expression in response to DNA damage

  7. In this study, in recombinant adenovirus-ASPP2-infected HepG2 cells, ASPP2 overexpression induces amphiregulin (zeige AREG ELISA Kits) expression in a p53 (zeige TP53 ELISA Kits)-dependent manner

  8. Downregulated expression of ASPP2 is associated with hepatocellular carcinoma.

  9. miR (zeige MLXIP ELISA Kits)-548d-3p/TP53BP2 pathway is critically involved in the proliferation and apoptosis of breast cancer cells and may be new therapeutic target of breast cancer cells.

  10. ASPP1 (zeige PPP1R13B ELISA Kits)/2-PP1 (zeige PPA1 ELISA Kits) complexes are required for chromosome segregation and kinetochore-microtubule attachments.

Tumor Protein P53 Binding Protein 2 (TP53BP2) Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit TP53BP2

  • tumor protein p53 binding protein, 2 (TP53BP2) Antikörper
  • tumor protein p53 binding protein, 2 (tp53bp2) Antikörper
  • si:dkeyp-34c12.2 (si:dkeyp-34c12.2) Antikörper
  • protein phosphatase 1, regulatory (inhibitor) subunit 13B (Ppp1r13b) Antikörper
  • transformation related protein 53 binding protein 2 (Trp53bp2) Antikörper
  • tumor protein p53 binding protein, 2 (Tp53bp2) Antikörper
  • 53BP2 Antikörper
  • AI449786 Antikörper
  • AI746547 Antikörper
  • ASPP1 Antikörper
  • ASPP2 Antikörper
  • AW545810 Antikörper
  • BBP Antikörper
  • P53BP2 Antikörper
  • p85 Antikörper
  • PPP1R13A Antikörper
  • Tp53bp2 Antikörper
  • Trp53bp2 Antikörper
  • wu:fa09h08 Antikörper
  • wu:fb04e08 Antikörper
  • X98550 Antikörper
  • zgc:85720 Antikörper

Bezeichner auf Proteinebene für TP53BP2

tumor protein p53 binding protein, 2 , apoptosis-stimulating of p53 protein 2-like , apoptosis-stimulating of p53 protein 1 , protein phosphatase 1 regulatory subunit 13B , transformation related protein 53 binding protein 2 , tumor protein p53-binding protein, 2 , apoptosis-stimulating of p53 protein 2 , p53-binding protein 2 , p53BP2 , tumor suppressor p53-binding protein 2 , fb04e08 , BCL2-binding protein , apoptosis-stimulating protein of p53, 2 , renal carcinoma antigen NY-REN-51

GENE ID SPEZIES
421329 Gallus gallus
457766 Pan troglodytes
548790 Xenopus (Silurana) tropicalis
568138 Danio rerio
705383 Macaca mulatta
100055278 Equus caballus
100221962 Taeniopygia guttata
100445132 Pongo abelii
100519863 Sus scrofa
21981 Mus musculus
209456 Mus musculus
407983 Danio rerio
446947 Xenopus laevis
7159 Homo sapiens
490397 Canis lupus familiaris
514474 Bos taurus
305025 Rattus norvegicus
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