anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) Antikörper

Acts as decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis. Zusätzlich bieten wir Ihnen Tumor Necrosis Factor Receptor Superfamily, Member 11b Kits (88) und Tumor Necrosis Factor Receptor Superfamily, Member 11b Proteine (36) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TNFRSF11B 4982 O00300
TNFRSF11B 18383 O08712
TNFRSF11B 25341 O08727
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Top anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b Antikörper auf antikoerper-online.de

Showing 10 out of 174 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Hund Kaninchen Unkonjugiert WB <b>WB Suggested Anti-TNFRSF11B Antibody Titration: </b>1.25ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Human Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$200.00
Details
Human Maus Unkonjugiert CyTOF, FACS, ICC, IF, IHC, IHC (fro), IHC (p), IP, WB Western blot analysis for OPG with IMG-103A antibody against Daudi cell lysate. Daudi cell lysate blot was incubated with ABIN252469 at a dilution of 1 µg/ml and the immunoreactivity was detected by enhanced chemiluminescence. Flow Cytometry: Osteoprotegerin/TNFRSF11B Antibody (98A1071) [ABIN2524695] - Intracellular staining of 10^6 HeLa cells using 0.2 ug of OPG antibody, 0.5 ul of PE secondary. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$444.19
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, ELISA, WB Osteoprotegerin staining of rat articular cartilage disk. Paraffin-embedded rat articular cartilage disk tissue is stained with Osteoprotegerin Antibody used at 1:200 dilution. 0.1 mg Anmelden zum Anzeigen 2 bis 6 Tage
$327.00
Details
Human Maus Unkonjugiert IHC, ELISA, WB Figure 1: Immunohistochemical analysis of paraffin-embedded mammary cancer tissues (left) and lung cancer tissues (right) using TNFRSF11B mouse mAb with DAB staining. Figure 2: Western blot analysis using TNFRSF11B mAb against HEK293 (1) and TNFRSF11B (AA: 22-401) -hIgGFc transfected HEK293 (2) cell lysate. 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$393.80
Details
Human Maus Unkonjugiert ICC, FACS, ELISA, WB Figure 1: Flow cytometric analysis of HL-60 cells using TNFRSF11B mouse mAb (green) and negative control (purple) . Figure 2: Immunofluorescence analysis of HL-60 cells using TNFRSF11B mouse mAb (green) . Blue: DRAQ5 fluorescent DNA dye. 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$393.80
Details
Human Kaninchen Unkonjugiert IF, IHC (p), WB Confocal immunofluorescent analysis of TNFRSF11B Antibody (Center) (ABIN657660) with NCI-H460 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Maus Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$478.50
Details
Human Kaninchen Unkonjugiert IF, IHC, WB Western blot analysis of extracts of various cell lines, using TNFRSF11B antibody. Immunohistochemistry of paraffin-embedded human stomach cancer using TNFRSF11B antibody at dilution of 1:200 (x400 lens) 100 μL Anmelden zum Anzeigen 16 Days
$334.02
Details
Human Maus Unkonjugiert IHC (p), WB Human Heart (formalin-fixed, paraffin-embedded) stained with TNFRSF11B antibody ABIN296455 at 5 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. Human Liver (formalin-fixed, paraffin-embedded) stained with TNFRSF11B antibody ABIN296455 at 5 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$451.00
Details

TNFRSF11B Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b Antikörper

  1. Human Monoclonal TNFRSF11B Primary Antibody für CyTOF, FACS - ABIN252469 : Kobayashi, Hashimoto, Miyamoto, Kanaoka, Miyazaki-Kawashita, Nakashima, Shibata, Kobayashi, Kato, Sakai: Force-induced osteoclast apoptosis in vivo is accompanied by elevation in transforming growth factor beta and osteoprotegerin expression. in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2001 (PubMed)
    Show all 25 Pubmed References

  2. Cow (Bovine) Polyclonal TNFRSF11B Primary Antibody für IHC, ELISA - ABIN1582232 : Fradet, Sorel, Bouazza, Goehrig, Dépalle, Bellahcène, Castronovo, Follet, Descotes, Aubin, Clézardin, Bonnelye: Dual function of ERR? in breast cancer and bone metastasis formation: implication of VEGF and osteoprotegerin. in Cancer research 2011 (PubMed)
    Show all 5 Pubmed References

  3. Human Monoclonal TNFRSF11B Primary Antibody für IHC, ELISA - ABIN969440 : Golledge, Biros, Clancy, Cooper, Palmer, Norman: A single-nucleotide polymorphism in the gene encoding osteoprotegerin is associated with diastolic blood pressure in older men. in American journal of hypertension 2009 (PubMed)
    Show all 2 Pubmed References

  4. Human Monoclonal TNFRSF11B Primary Antibody für ICC, FACS - ABIN969439 : Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ... in American journal of human genetics 2009 (PubMed)
    Show all 2 Pubmed References

  5. Human Monoclonal TNFRSF11B Primary Antibody für WB - ABIN2668734 : Sood, Balasubramanian, Higham, Fernando, Harrison: Osteoprotegerin (OPG) and related proteins (RANK, RANKL and TRAIL) in thyroid disease. in World journal of surgery 2011 (PubMed)

  6. Human Monoclonal TNFRSF11B Primary Antibody für ELISA, WB - ABIN2475981 : Westheimer: Why nature chose phosphates. in Science (New York, N.Y.) 1987 (PubMed)
    Show all 3 Pubmed References

Weitere Antikörper gegen Tumor Necrosis Factor Receptor Superfamily, Member 11b Interaktionspartner

Human Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) Interaktionspartner

  1. High OPG expression is associated with colorectal carcinoma.

  2. Data suggest that elevated plasma levels of osteoprotegerin/TNFRSF11B correlate with increased risk of cardiovascular comorbidities in children and adolescents with type 1 diabetes (as compared to healthy control subjects); thus, osteoprotegerin/TNFRSF11B may serve as biomarker of cardiovascular risk in these patients. This study was conducted in Tunisia.

  3. Studies showed that the central hypothalamic-pituitary regulatory system, via it's relative hormones, seems to control OPG/RANKL (zeige TNFSF11 Antikörper)/RANK system function, and the pulsatility and circadian rhythmicity of these hormones may induce an oscillatory fluctuation of the OPG/ RANKL (zeige TNFSF11 Antikörper) ratio. Also, psycological characteristics may provoke a shift of the OPG/ RANKL (zeige TNFSF11 Antikörper) ratio towards an unbalanced or a balanced status. [review]

  4. Formulation and in vitro and in vivo evaluation of a new osteoprotegerin-chitosan gel for bone tissue regeneration

  5. The RANKL/OPG (zeige TNFSF11 Antikörper) ratio significantly increased in the presence of bone metastasis with appropriate sensitivity and specificity (73% and 72%, respectively) at a cutoff of >/=0.14 for the detection of bone metastasis. Serum OPG and RANKL/OPG (zeige TNFSF11 Antikörper) ratios are promising biomarkers for detecting bone metastasis in breast cancer patients.

  6. Osteoprotegerin facilitates pulmonary arterial hypertension pathogenesis by regulating pulmonary arterial smooth muscle cell proliferation via integrin alphavbeta3 (zeige ITGAV Antikörper)/FAK (zeige PTK2 Antikörper)/AKT (zeige AKT1 Antikörper) signaling pathway.

  7. Elevated osteoprotegerin concentration is associated with an increased risk of incident cardiovascular disease in the general population

  8. Physical activity does not increase circulating osteoprotegerin level.

  9. OPG may be a potential driver of lung cancer cells and therefore might have potential in therapy and diagnostics.

  10. our findings suggest OPG is a downstream effector of IL1B (zeige IL1B Antikörper)-mediated invasion in breast cancer cells.

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) Interaktionspartner

  1. findings demonstrate that mTORC1 activation-stimulated RANKL (zeige TNFSF11 Antikörper) expression in B cells is sufficient to induce bone loss and osteoporosis. The study also established a link between mTORC1 and the RANKL/OPG (zeige TNFSF11 Antikörper) axis via negative regulation of beta-catenin (zeige CTNNB1 Antikörper).

  2. RANK/RANKL (zeige TNFSF11 Antikörper) signaling is involved in the androgen deprivation therapy-induced acceleration of bone metastasis in castration-insensitive prostate cancer and is inhibited by osteoprotegerin to prevent bone metastasis.

  3. endocortical resorption is driven by reduced OPG (zeige TNFSF11 Antikörper) rather than elevated RANKL (zeige TNFSF11 Antikörper) expression

  4. Diabetes significantly increased OPG (zeige TNFSF11 Antikörper) and the OPG (zeige TNFSF11 Antikörper)/TRAIL ratio expression in the aorta, while dyslipidemia was the major determinant of the changes observed in the heart, where it significantly increased OPG (zeige TNFSF11 Antikörper) and reduced TRAIL expression, thus increasing cardiac OPG (zeige TNFSF11 Antikörper)/TRAIL ratio.

  5. These discoveries strongly suggest that Heparan Sulfate plays an active role in regulating OPG-RANKL (zeige TNFSF11 Antikörper) interaction and osteoclastogenesis.

  6. OPG (zeige TNFSF11 Antikörper) plays an important role in regulating bone marrow mesenchymal stem cells differentiation and bone marrow adipogenesis.

  7. These data suggested that OPG (zeige TNFSF11 Antikörper) played an important role in maintaining the homeostasis of articular cartilage of femoral head.

  8. Data show that p38alpha (zeige MAPK14 Antikörper) mitogen-activated protein kinase (zeige MAPK1 Antikörper) (MAPK (zeige MAPK1 Antikörper)) in paired related homeobox 1 (zeige PRRX1 Antikörper) protein (Prx1 (zeige PRDX1 Antikörper)+) bone marrow-derived mesenchymal stromal cells acts to preserve the bone by sustaining osteoprotegerin (OPG) production.

  9. OPG (zeige TNFSF11 Antikörper) expression in chondrocyte increases bone mass in the proximal metaphysis of tibiae through negative regulation of osteoclast formation.

  10. the generation of Rag2GFP+ regulatory T cells is unaltered in Tnfrsf11b(-/-) mice

Rabbit Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) Interaktionspartner

  1. The OPG (zeige TNFSF11 Antikörper) expression levels decreased while those of RANKL (zeige TNFSF11 Antikörper) and RUNX2 (zeige RUNX2 Antikörper) increased during orthodontic tooth movement, which suggested that they play a role in the osteogenesis process and the reconstruction of periodontal tissue.

  2. Low-frequency vibration may promote the osteogenic differentiation capability of BMSC probably through regulating the OPG/RANKL (zeige TNFSF11 Antikörper) mRNA expression.

Pig (Porcine) Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) Interaktionspartner

  1. Regional variation of periosteal activity at the mandibular ramus is regulated by differential expression of osteoprotegerin.

Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) Antigen-Profil

Protein Überblick

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.

Genbezeichner und Symbole assoziert mit TNFRSF11B

  • TNF receptor superfamily member 11b (TNFRSF11B) Antikörper
  • tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) (Tnfrsf11b) Antikörper
  • TNF receptor superfamily member 11B (Tnfrsf11b) Antikörper
  • tumor necrosis factor receptor superfamily member 11b S homeolog (tnfrsf11b.S) Antikörper
  • tumor necrosis factor receptor superfamily, member 11b (TNFRSF11B) Antikörper
  • ocif Antikörper
  • opg Antikörper
  • tr1 Antikörper

Bezeichner auf Proteinebene für TNFRSF11B

osteoclastogenesis inhibitory factor , osteoprotegerin , tumor necrosis factor receptor superfamily member 11B , Osteoprotegerin , tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) , tumor necrosis factor receptor superfamily, member 11b , tumor necrosis factor receptor superfamily member 11B-like

GENE ID SPEZIES
4982 Homo sapiens
18383 Mus musculus
25341 Rattus norvegicus
464351 Pan troglodytes
523822 Bos taurus
100037695 Ovis aries
444716 Xenopus laevis
482025 Canis lupus familiaris
701850 Macaca mulatta
100399751 Callithrix jacchus
100433420 Pongo abelii
100465761 Ailuropoda melanoleuca
100599407 Nomascus leucogenys
100348133 Oryctolagus cuniculus
100049688 Sus scrofa
100860896 Capra hircus
100065885 Equus caballus
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