Tudor Domain Containing 3 Proteine (TDRD3)

Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. Zusätzlich bieten wir Ihnen TDRD3 Antikörper (16) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
TDRD3 81550 Q9H7E2
TDRD3 219249 Q91W18
Ratte TDRD3 TDRD3 306066 Q66HC1
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Showing 3 out of 3 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process REN dissolution curves 1 mg Anmelden zum Anzeigen 66 Days
10.536,00 €
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 16 Days
748,00 €
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TDRD3 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine)

Weitere Proteine zu Tudor Domain Containing 3 (TDRD3) Interaktionspartnern

Human Tudor Domain Containing 3 (TDRD3) Interaktionspartner

  1. Top3b (zeige TOP3B Proteine) proteins from several animals associate with polyribosomes, which are units of mRNA translation, whereas the Top3 homologs from E. coli and yeast lack the association. The Top3b (zeige TOP3B Proteine)-polyribosome association requires TDRD3, which directly interacts with Top3beta and is present in animals but not bacteria or yeast.

  2. The binding specificity and affinity of the Tudor domains of TDRD3, SMN (zeige STMN1 Proteine) and SPF30 (zeige SMNDC1 Proteine) proteins were characterized quantitatively.

  3. The TDRD3 is an effector molecule that promotes transcription by binding methylarginine marks on histone tails.

  4. Tudor domain of TDRD3 was required for its recruitment to cytoplasmic stress granules.

  5. propose a contribution of Tdrd3 to FMRP (zeige FMR1 Proteine)-mediated translational repression and suggest that the loss of the FMRP (zeige FMR1 Proteine)-Tdrd3 interaction caused by the I304N mutation might contribute to the pathogenesis of Fragile X (zeige FMR1 Proteine) syndrome

TDRD3 Protein Überblick

Protein Überblick

Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In nucleus, acts as a core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine- methylated loci. In cytoplasm, may play a role in the assembly and/or disassembly of mRNA stress granules and in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins (By similarity).

Genbezeichner und Symbole assoziert mit TDRD3

  • tudor domain containing 3 (LOC100217625)
  • tudor domain containing 3 (TDRD3)
  • tudor domain containing 3 (Tdrd3)
  • tudor domain containing 3 (tdrd3)
  • 4732418C03Rik Protein
  • 6720468N18 Protein
  • zgc:77174 Protein

Bezeichner auf Proteinebene für TDRD3

tudor domain containing 3 , tudor domain-containing protein 3

GENE ID SPEZIES
100217625 Taeniopygia guttata
81550 Homo sapiens
219249 Mus musculus
306066 Rattus norvegicus
537918 Bos taurus
418823 Gallus gallus
402828 Danio rerio
431810 Xenopus laevis
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