anti-Tu Translation Elongation Factor, Mitochondrial (Tufm) Antikörper

Tufm encodes a protein which participates in protein translation in mitochondria. Zusätzlich bieten wir Ihnen Tu Translation Elongation Factor, Mitochondrial Proteine (26) und Tu Translation Elongation Factor, Mitochondrial Kits (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
Tufm 7284 P49411
Tufm 233870 Q8BFR5
Tufm 293481 P85834
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Top anti-Tu Translation Elongation Factor, Mitochondrial Antikörper auf antikoerper-online.de

Showing 10 out of 66 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-TUFM Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Hela cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB Western blot analysis of TUFM Antibody (N-term) (ABIN389459) in Ramos, Hela cell line lysates (35 µg/lane). TUFM (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with TUFM Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of TUFM Antibody (N-term) in Ramos cell line lysates (35ug/lane). TUFM (arrow) was detected using the purified Pab. 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of TUFM (arrow) using rabbit polyclonal TUFM Antibody (C-term) . 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the TUFM gene. 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using TUFM Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of TUFM (arrow) using rabbit polyclonal TUFM Antibody (C-term) (ABIN656840). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the TUFM gene. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IP, IHC (p), WB IP Image TUFM antibody immunoprecipitates TUFM protein in IP experiments. IP samples: HepG2 whole cell extract A. 35 μg HepG2 whole cell extract B. Control with 4 μg of preimmune Rabbit IgG C. Immunoprecipitation of TUFM protein by 4 μg TUFM antibody , 10 % SDS-PAGE The immunoprecipitated TUFM protein was detected by TUFM antibody , diluted at 1:1000. [EasyBlot anti-rabbit IgG  was used as a secondary reagent] WB Image Sample (30 ug of whole cell lysate) A:NIH-3T3 10% SDS PAGE antibody diluted at 1:1000 100 μL Anmelden zum Anzeigen 5 bis 7 Tage
357,24 €
Details
Human Kaninchen Unkonjugiert IP, IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded SNU16 xenograft, using TUFM, antibody at 1:100 dilution. IP Image TUFM antibody [N3C3] immunoprecipitates TUFM protein in IP experiments. IP samples: HepG2 whole cell extract A. 35 μg HepG2 whole cell extract B. Control with 4 μg of preimmune Rabbit IgG C. Immunoprecipitation of TUFM protein by 4 μg TUFM antibody [N3C3] , 10 % SDS-PAGE The immunoprecipitated TUFM protein was detected by TUFM antibody [N3C3] , diluted at 1:1000. [EasyBlot anti-rabbit IgG  was used as a secondary reagent] 100 μL Anmelden zum Anzeigen 5 bis 7 Tage
357,24 €
Details
Human Maus Unkonjugiert ELISA Detection limit for recombinant GST tagged TUFM is approximately 0.3ng/ml as a capture antibody. 100 μg Anmelden zum Anzeigen 7 bis 8 Tage
369,60 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB   0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details

Tufm Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human ,
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Mouse (Murine) ,


Rat (Rattus) ,
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Am meisten referenzierte anti-Tu Translation Elongation Factor, Mitochondrial Antikörper

  1. Human Polyclonal Tufm Primary Antibody für EIA, WB - ABIN955399 : Sasarman, Antonicka, Shoubridge: The A3243G tRNALeu(UUR) MELAS mutation causes amino acid misincorporation and a combined respiratory chain assembly defect partially suppressed by overexpression of EFTu and EFG2. in Human molecular genetics 2008 (PubMed)
    Zeige alle 4 Referenzen für 955399

  2. Cow (Bovine) Polyclonal Tufm Primary Antibody für WB - ABIN2787734 : Valente, Tiranti, Marsano, Malfatti, Fernandez-Vizarra, Donnini, Mereghetti, De Gioia, Burlina, Castellan, Comi, Savasta, Ferrero, Zeviani: Infantile encephalopathy and defective mitochondrial DNA translation in patients with mutations of mitochondrial elongation factors EFG1 and EFTu. in American journal of human genetics 2006 (PubMed)
    Zeige alle 2 Referenzen für 2787734

  3. Human Polyclonal Tufm Primary Antibody für ICC, IF - ABIN4363539 : Lundberg, Fagerberg, Klevebring, Matic, Geiger, Cox, Algenäs, Lundeberg, Mann, Uhlen: Defining the transcriptome and proteome in three functionally different human cell lines. in Molecular systems biology 2010 (PubMed)
    Zeige alle 2 Referenzen für 4363539

  4. Human Polyclonal Tufm Primary Antibody für EIA, WB - ABIN453444 : Valente, Shigi, Suzuki, Zeviani: The R336Q mutation in human mitochondrial EFTu prevents the formation of an active mt-EFTu.GTP.aa-tRNA ternary complex. in Biochimica et biophysica acta 2009 (PubMed)
    Zeige alle 2 Referenzen für 453444

  5. Human Polyclonal Tufm Primary Antibody für FACS, IHC (p) - ABIN389459 : Bogenhagen, Rousseau, Burke: The layered structure of human mitochondrial DNA nucleoids. in The Journal of biological chemistry 2008 (PubMed)
    Zeige alle 2 Referenzen für 389459

  6. Human Monoclonal Tufm Primary Antibody für ELISA - ABIN563293 : Tomaino, Cappello, Capello, Fredolini, Ponzetto, Novarino, Ciuffreda, Bertetto, De Angelis, Gaia, Salacone, Milella, Nisticò, Alessio, Chiarle, Giuffrida, Giovarelli, Novelli: Autoantibody signature in human ductal pancreatic adenocarcinoma. in Journal of proteome research 2007 (PubMed)

  7. Human Polyclonal Tufm Primary Antibody für IHC, ELISA - ABIN1534881 : Ling, Merante, Chen, Duff, Duncan, Robinson: The human mitochondrial elongation factor tu (EF-Tu) gene: cDNA sequence, genomic localization, genomic structure, and identification of a pseudogene. in Gene 1997 (PubMed)

Weitere Antikörper gegen Tu Translation Elongation Factor, Mitochondrial Interaktionspartner

Human Tu Translation Elongation Factor, Mitochondrial (Tufm) Interaktionspartner

  1. we identify a novel signaling hub centering on the NLRX1 (zeige NLRX1 Antikörper) TUFM protein complex, promoting autophagic flux. Defects in the expression of either NLRX1 (zeige NLRX1 Antikörper) or TUFM result in compromised autophagy when treated with EGFR (zeige EGFR Antikörper) inhibitors.These findings expand our understanding of the components involved in head and neck squamous cell carcinoma autophagy machinery that responds to EGFR (zeige EGFR Antikörper) inhibitors.

  2. TUFM is a novel regulator of epithelial-mesenchymal transition (EMT (zeige ITK Antikörper)); there may be a molecular link between mitochondrial dysfunction and EMT (zeige ITK Antikörper) induction

  3. NLRX1 (zeige NLRX1 Antikörper) and TUFM work in concert to reduce cytokine response and augment autophagy.

  4. Increased expression of TUFM is a promising new prognostic indicator for colorectal carcinoma.

  5. By recruiting Atg5 (zeige ATG5 Antikörper)-Atg12 (zeige ATG12 Antikörper) and NLRX1 (zeige NLRX1 Antikörper), TUFM serves as a nodal checkpoint of the RIG-I (zeige DDX58 Antikörper)-MAVS (zeige MAVS Antikörper) axis. It acts similarly to NLRX1 (zeige NLRX1 Antikörper) by inhibiting RigI (zeige DDX58 Antikörper)-like-receptor-induced IFN-I but promoting autophagy.

  6. Genetic investigation of patients with defective mitochondrial translation led to the discovery of novel mutations in the mitochondrial elongation factor G1 (EFG1 (zeige GFM1 Antikörper)) in one affected baby and in the mitochondrial elongation factor Tu (zeige EEF1A1 Antikörper) (EFTu) in another one

  7. Myoblasts isolated from the MELAS patients show A3243G mutation in tRNALeu(UUR) produces a severe respiratory chain deficiency and this phenotype can be partially suppressed by overexpression of EFTu and EFG2 (zeige GFM2 Antikörper).

  8. Results suggest that the R336Q mutant mt-EFTu variant fails to bind to aminoacylated mitochondrial tRNAs, thus explaining the observed impairment of mitochondrial translation.

Cow (Bovine) Tu Translation Elongation Factor, Mitochondrial (Tufm) Interaktionspartner

  1. Loss of activity is caused by a significant reduction in the ability of EF-Ts (zeige TSFM Antikörper)(mt) R325W to bind EF-Tu(mt), leading to a defect in nucleotide exchange.

  2. Recombinant mitochondrial EF-Tu prevents thermal aggregation of proteins and enhances protein refolding in vitro.

  3. The arginine residue at position 335 of bovine mitochondrial elongation factor Tu (EF-Tu (zeige EEF1A1 Antikörper)) plays an important role in the binding and EF-Tu-mediated delivery of mitochondrial aminoacyl-tRNAs to the A-site of the ribosome.

Mouse (Murine) Tu Translation Elongation Factor, Mitochondrial (Tufm) Interaktionspartner

  1. By recruiting Atg5 (zeige ATG5 Antikörper)-Atg12 (zeige ATG12 Antikörper) and NLRX1 (zeige NLRX1 Antikörper), TUFM serves as a nodal checkpoint of the RIG-I (zeige DDX58 Antikörper)-MAVS (zeige MAVS Antikörper) axis. It acts similarly to NLRX1 (zeige NLRX1 Antikörper) by inhibiting RigI (zeige DDX58 Antikörper)-like-receptor-induced IFN-I but promoting autophagy.

Tu Translation Elongation Factor, Mitochondrial (Tufm) Antigen-Profil

Protein Überblick

This gene encodes a protein which participates in protein translation in mitochondria. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency resulting in lactic acidosis and fatal encephalopathy. A pseudogene has been identified on chromosome 17.

Genbezeichner und Symbole assoziert mit Tufm

  • Tu translation elongation factor, mitochondrial (TUFM) Antikörper
  • Tu translation elongation factor, mitochondrial (tufm) Antikörper
  • Tu translation elongation factor, mitochondrial (Tufm) Antikörper
  • 2300002G02Rik Antikörper
  • C76308 Antikörper
  • C76389 Antikörper
  • COXPD4 Antikörper
  • D250 Antikörper
  • EF-TuMT Antikörper
  • EFTU Antikörper
  • fi06f04 Antikörper
  • P43 Antikörper
  • TUFM Antikörper
  • wu:fi06f04 Antikörper
  • zgc:110766 Antikörper

Bezeichner auf Proteinebene für Tufm

Tu translation elongation factor, mitochondrial , elongation factor Tu, mitochondrial-like , elongation factor Tu, mitochondrial , EF-Tu

GENE ID SPEZIES
454018 Pan troglodytes
705462 Macaca mulatta
100455214 Pongo abelii
541378 Danio rerio
7284 Homo sapiens
479796 Canis lupus familiaris
281556 Bos taurus
233870 Mus musculus
293481 Rattus norvegicus
430889 Gallus gallus
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