anti-Tripeptidyl Peptidase II (Tpp2) Antikörper

Tpp2 encodes a mammalian peptidase that, at neutral pH, removes tripeptides from the N terminus of longer peptides. Zusätzlich bieten wir Ihnen Tpp2 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
Tpp2 7174 P29144
Tpp2 22019 Q64514
Tpp2 81815 Q64560
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Top anti-Tpp2 Antikörper auf antikoerper-online.de

Showing 10 out of 15 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-TPP2 Antibody Titration: 1.0 ug/ml Positive Control: Jurkat Whole Cell TPP2 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
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Human Huhn Unkonjugiert WB   100 μL Anmelden zum Anzeigen 2 bis 4 Tage
356,40 €
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Meerschweinchen Kaninchen Unkonjugiert WB   50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
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Human Kaninchen Unkonjugiert ICC, IF Immunocytochemistry/Immunofluorescence: Tripeptidyl peptidase II Antibody  - Staining of human cell line RH-30 shows localization to nuclear bodies & cytosol. 100 μL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
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Human Kaninchen Unkonjugiert IHC, IHC (p), WB Western Blot: Tripeptidyl peptidase II Antibody  - Analysis in mouse cell line NIH-3T3 and rat cell line NBT-II. Western Blot: Tripeptidyl peptidase II Antibody  - Analysis in human cell line Jurkat. 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
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Human Kaninchen Unkonjugiert IC, IF, IHC, WB Immunofluorescent analysis of TPP2 staining in U2OS cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody i Immunohistochemical analysis of TPP2 staining in mouse lung formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the ant 200 μL Anmelden zum Anzeigen 11 bis 13 Tage
464,29 €
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Human Kaninchen Unkonjugiert IHC, WB Western blot analysis of extracts of various cell lines, using TPP2 antibody. Immunohistochemistry of paraffin-embedded Mouse lung using TPP2 antibody at dilution of 1:100 (x400 lens). 100 μL Anmelden zum Anzeigen 12 Days
261,90 €
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Human Kaninchen Unkonjugiert IF, IHC, WB   50 μL Anmelden zum Anzeigen 11 bis 14 Tage
460,95 €
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Human Kaninchen Unkonjugiert IF, IHC, ELISA, WB   50 μL Anmelden zum Anzeigen 11 bis 15 Tage
298,57 €
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Human Kaninchen Unkonjugiert IHC (p), WB   100 μL Anmelden zum Anzeigen 7 bis 8 Tage
480,00 €
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Tpp2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Human ,
,

Mouse (Murine)


Rat (Rattus)


Weitere Antikörper gegen Tpp2 Interaktionspartner

Fruit Fly (Drosophila melanogaster) Tripeptidyl Peptidase II (Tpp2) Interaktionspartner

  1. Previously unknown differences between TPP II orthologues and subtilisin as well as features that might be conserved within the entire family of subtilisin-like serine peptidases.

  2. a systematic kinetic analysis of wild type Drosophila melanogaster TPPII and five point mutants of the double-Glu (zeige SLC2A1 Antikörper)-motif (E312/E343) involving natural substrates were performed.

  3. The structure suggests a model for activation of TPP II involving the relocation of a flexible loop and a repositioning of the active-site serine, coupling it to holocomplex assembly and active-site sequestration.

  4. The 150 kDa subunits of TPPII form a superstructure composed of 2 segmented & twisted (zeige POMT2 Antikörper) strands. Each strand is 12.5 nm in width & composed of 11 segments that enclose a central channel.

  5. the unique spindle form of the holo-complex of TPP II represents an assembly motif stabilizing a highly active state

Arabidopsis thaliana Tripeptidyl Peptidase II (Tpp2) Interaktionspartner

  1. The purification and characterization of tripeptidyl peptidase II from Arabidopsis thaliana is reported.

Human Tripeptidyl Peptidase II (Tpp2) Interaktionspartner

  1. Novel interactions of TPPII, p53 (zeige TP53 Antikörper), and SIRT7 (zeige SIRT7 Antikörper) presented in this study might contribute to the knowledge of the regulatory effects of these proteins on apoptotic pathways and to the understanding mechanisms of aging and lifespan regulation.

  2. TPP2 mediates many important cellular functions by controlling ERK1 (zeige MAPK3 Antikörper) and ERK2 (zeige MAPK1 Antikörper) phosphorylation.

  3. Early-onset Evans syndrome, immunodeficiency, and premature immunosenescence associated with TPP2 deficiency have been described in two consanguineous siblings.

  4. Study found that autosomal recessive TPP2 mutations cause recurrent infections, autoimmunity, and neurodevelopmental delay in humans.

  5. TPPII, MYBBP1A (zeige MYBBP1A Antikörper) and CDK2 (zeige CDK2 Antikörper) form a protein-protein interaction network.

  6. Previously unknown differences between TPP II orthologues and subtilisin as well as features that might be conserved within the entire family of subtilisin-like serine peptidases.

  7. Study showed that overexpression of Tripeptidyl peptidase II (TPP2) occurs frequently during oral carcinogenesis and might be associated with the progression of Oral Squamous Cell Carcinoma (OSCC) via Spindle Assembly Checkpoint(SAC (zeige ADCY10 Antikörper)) activation.

  8. obtained a 3D structure of the human TPPII

  9. Current knowledge about TPPII with a focus on structural aspects.

  10. Results suggest an important function of TPPII in the maintenance of viral growth and may have implications for anti-viral therapy.

Mouse (Murine) Tripeptidyl Peptidase II (Tpp2) Interaktionspartner

  1. Data indicate that TPPII can regulate sperm maturation by modulating intracellular Ca(2 (zeige CA2 Antikörper)+) stores via the type 3 RyR (zeige RYR1 Antikörper).

  2. Previously unknown differences between TPP II orthologues and subtilisin as well as features that might be conserved within the entire family of subtilisin-like serine peptidases.

  3. Tripeptidyl peptidase II is crucial for nucleoprotein epitope generation during major histocompatibility complex class I complex viral antigen processing both in the presence and absence of lactacystin-sensitive proteasome action.

  4. TPPII is not generally required for the production of major histocompatibility class I-restricted peptides, but presentation of some peptides can be negatively affected by TPPII.

  5. Data show that mice that were homozygous for an insertion in the Tpp2 locus were embryonic lethal and Tpp2 heterozygous mutants were lean compared with wild-type littermates, although food intake was normal.

  6. The data suggest a moderate, predominantly destructive role of TPPII in class I Ag processing.

  7. TPPII is important for maintaining normal cellular and systemic physiology, which may be relevant for potential therapeutic applications of TPPII inhibitors

  8. These results do not support a generally important role of TPPII for viability and proliferation of transformed cells or their p53 (zeige TP53 Antikörper)-mediated DNA damage response.

  9. These data indicate that while TPPII contributes to the trimming of peptides with very long N-terminal extensions, TPPII is not essential for generating most MHC class I-presented peptides or for stimulating CTL responses to several Ags (zeige GLA Antikörper) in vivo.

Tpp2 Antigen-Profil

Protein Überblick

This gene encodes a mammalian peptidase that, at neutral pH, removes tripeptides from the N terminus of longer peptides. The protein has a specialized function that is essential for some MHC class I antigen presentation. The protein is a high molecular mass serine exopeptidase\; the amino acid sequence surrounding the serine residue at the active site is similar to the peptidases of the subtilisin class rather than the trypsin class.

Genbezeichner und Symbole assoziert mit Tpp2

  • tripeptidyl-peptidase II (TppII) Antikörper
  • tripeptidyl peptidase II (TPP2) Antikörper
  • tripeptidyl peptidase II (tpp2) Antikörper
  • tripeptidyl peptidase ii (AaeL_AAEL007174) Antikörper
  • tripeptidyl peptidase ii (AaeL_AAEL009516) Antikörper
  • tripeptidyl peptidase ii (AaeL_AAEL010192) Antikörper
  • tripeptidyl peptidase II (LOC100359134) Antikörper
  • tripeptidyl peptidase II (Tpp2) Antikörper
  • anon-WO0118547.127 Antikörper
  • CG3991 Antikörper
  • DKFZp468E2313 Antikörper
  • Dmel\\CG3991 Antikörper
  • dTPP II Antikörper
  • dTPPII Antikörper
  • l(2)k14301 Antikörper
  • MGC83244 Antikörper
  • T13K14.10 Antikörper
  • T13K14_10 Antikörper
  • TPP-2 Antikörper
  • TPP2 Antikörper
  • TPP II Antikörper
  • TppII Antikörper
  • tripeptidyl peptidase ii Antikörper

Bezeichner auf Proteinebene für Tpp2

CG3991-PA , CG3991-PD , TppII-PA , TppII-PD , Tripeptidyl-peptidase II , tripeptidyl peptidase II , tripeptidylpeptidase II , tripeptidyl peptidase ii , tripeptidyl-peptidase 2 , TPP-II , tripeptidyl aminopeptidase , tripeptidyl-peptidase II

GENE ID SPEZIES
36444 Drosophila melanogaster
428020 Gallus gallus
443806 Xenopus laevis
827833 Arabidopsis thaliana
5568882 Aedes aegypti
5572106 Aedes aegypti
5572975 Aedes aegypti
100101674 Xenopus (Silurana) tropicalis
100172493 Pongo abelii
100359134 Oryctolagus cuniculus
100552517 Anolis carolinensis
7174 Homo sapiens
22019 Mus musculus
81815 Rattus norvegicus
526052 Bos taurus
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