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Trafficking Protein Particle Complex 2 Proteine (TRAPPC2)

The protein encoded by TRAPPC2 is thought to be part of a large multi-subunit complex involved in the targeting and fusion of endoplasmic reticulum-to-Golgi transport vesicles with their acceptor compartment. Zusätzlich bieten wir Ihnen TRAPPC2 Antikörper (50) und TRAPPC2 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
TRAPPC2 6399 P0DI81 , P0DI82
TRAPPC2 66226 Q9CQP2
TRAPPC2 501550  
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Top TRAPPC2 Proteine auf antikoerper-online.de

Showing 10 out of 13 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Escherichia coli (E. coli) Human His tag 20 μg Anmelden zum Anzeigen 11 bis 15 Tage
303,81 €
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
Details
HOST_Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
Details
Hefe Wildschwein His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.189,52 €
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.189,52 €
Details
Hefe Hund His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.189,52 €
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Hefe Xenopus tropicalis His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.189,52 €
Details
Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.189,52 €
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
Details

TRAPPC2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, , ,
Mouse (Murine)

Rat (Rattus)

Am meisten referenzierte TRAPPC2 Proteine

  1. Human TRAPPC2 Protein expressed in Escherichia coli (E. coli) - ABIN1098448 : Gécz, Shaw, Bellon, de Barros Lopes: Human wild-type SEDL protein functionally complements yeast Trs20p but some naturally occurring SEDL mutants do not. in Gene 2003 (PubMed)

  2. Human TRAPPC2 Protein expressed in Wheat germ - ABIN1323540 : Liu, Wang, Zhu, Zhang, Xing, Wu, Song, Fan: Interaction of Sedlin with PAM14. in Journal of cellular biochemistry 2010 (PubMed)

Weitere Proteine zu Trafficking Protein Particle Complex 2 (TRAPPC2) Interaktionspartnern

Human Trafficking Protein Particle Complex 2 (TRAPPC2) Interaktionspartner

  1. c.93+5G>A mutation in the TRAPPC2 gene is associated with X-linked spondyloepiphyseal dysplasia in a Chinese family.

  2. Data suggest that c.267_271delAAGAC frameshift mutation of the exon 5 of the spondyloepiphyseal dysplasia, late protein (SEDL) gene probably underlies the disease in the family.

  3. identification of the novel nonsense mutation (c.61G>T) in the SEDT family enables carrier detection, genetic counseling, and prenatal diagnosis.

  4. A novel splicing mutation in the SEDL gene causes spondyloepiphyseal dysplasia tarda in a large Chinese pedigree.

  5. Studies indicate that splice site mutation that leads to aberrant splicing often causes genetic skeletal system disease, like COL1A1 (zeige COL1A1 Proteine), SEDL and LRP (zeige RPSA Proteine).

  6. Sedlin bound and promoted efficient cycling of Sar1, a guanosine triphosphatase that can constrict membranes, and thus allowed nascent carriers to grow and incorporate procollagen prefibrils.

  7. Data show that a disease-causing mutation of TRAPPC2, D47Y, failed to interact with either TRAPPC9 or TRAPPC8, suggesting that aspartate 47 in TRAPPC2 is at or near the site of interaction with TRAPPC9 or TRAPPC8.

  8. Data indicate SPATA4 interacts with the C2 portion of the TRAPP complex.

  9. SEDLIN is present in the nucleus, forms homodimers and that SEDT-associated mutations cause a loss of interaction with the transcription factors MBP1, PITX1 (zeige PITX1 Proteine) and SF1 (zeige NR5A1 Proteine).

  10. The results suggest that nucleus-localized Sedlin may play a role in regulation of transcriptional activities of the MRG (zeige FABP7 Proteine) family of transcription factors via binding to PAM14 (zeige MRFAP1 Proteine).

Mouse (Murine) Trafficking Protein Particle Complex 2 (TRAPPC2) Interaktionspartner

  1. x-ray crystallography analysis of mouse SEDL

  2. The sedlin mutations S73L, F83S and V130D cause SEDT by sedlin misfolding, whereas the D47Y mutation may influence normal TRAPP (transport protein particle) dynamics.

TRAPPC2 Protein Überblick

Protein Überblick

The protein encoded by this gene is thought to be part of a large multi-subunit complex involved in the targeting and fusion of endoplasmic reticulum-to-Golgi transport vesicles with their acceptor compartment. In addition, the encoded protein can bind c-myc promoter-binding protein 1 and block its transcriptional repression capability. Mutations in this gene are a cause of spondyloepiphyseal dysplasia tarda (SEDT). A processed pseudogene of this gene is located on chromosome 19, and other pseudogenes are found on chromosomes 8 and Y. Alternatively spliced transcript variants have been found for this gene.

Genbezeichner und Symbole assoziert mit TRAPPC2

  • trafficking protein particle complex 2 (trappc2)
  • trafficking protein particle complex 2 (TRAPPC2)
  • trafficking protein particle complex 2 (Trappc2)
  • 1110066L09Rik Protein
  • 1810064C02Rik Protein
  • AW496358 Protein
  • hYP38334 Protein
  • MIP-2A Protein
  • MIP2A Protein
  • RGD1306925 Protein
  • Sedl Protein
  • SEDT Protein
  • TRAPPC2P1 Protein
  • TRS20 Protein
  • ZNF547L Protein

Bezeichner auf Proteinebene für TRAPPC2

trafficking protein particle complex 2 , sedlin , trafficking protein particle complex subunit 2 , spondyloepiphyseal dysplasia tarda protein , spondyloepiphyseal dysplasia, late , trafficking protein particle complex protein 2

GENE ID SPEZIES
549396 Xenopus (Silurana) tropicalis
6399 Homo sapiens
66226 Mus musculus
501550 Rattus norvegicus
494644 Xenopus laevis
418634 Gallus gallus
480840 Canis lupus familiaris
616748 Bos taurus
100513447 Sus scrofa
Ausgewählte Anbieter für TRAPPC2 Proteine (TRAPPC2)
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