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May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton May promote apoptosis, via its cleavage by caspase-3 (By similarity). Zusätzlich bieten wir Ihnen Tensin 4 Antikörper (50) und Tensin 4 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.
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Conclude that in colorectal cancer, Cten is upregulated by EGFR (zeige EGFR Proteine) and Kras but downregulated by STAT3 (zeige STAT3 Proteine).
Tensin4 is up-regulated by EGF-induced ERK1/2 activity and promotes cell proliferation and migration in hepatocellular carcinoma
Cten expression mediates invasion of human lung cancer cells and is upregulated by epidermal growth factor (zeige EGF Proteine) via STAT3 (zeige STAT3 Proteine).
Findings indicate that induction of Cten protein expression is a relatively early event in melanoma progression, and that Cten has the potential to serve as a prognostic marker for primary melanoma patients.
Up-regulated cten modulates cell migration induced by FGF2 (zeige FGF2 Proteine).
Significant correlation between MET and TNS4 expression in human colon carcinoma and ovarian carcinoma suggests TNS4 plays a critical role in MET stability in cancer.
CTEN regulates EGFR (zeige EGFR Proteine) protein levels through a posttranslational mechanism.
Phylogenetic analysis, expression patterns, and transcriptional regulation of human CTEN gene.
Show an oncogenic role for CTEN in pancreatic cancer through promotion of colony formation and cell motility.
conclude that, in the colon and pancreas, Cten is a downstream target of Kras and may be a mechanism through which Kras regulates of cell motility
May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton May promote apoptosis, via its cleavage by caspase-3 (By similarity). Cytoplasm, cytoskeleton (By similarity).
, C-terminal tensin-like
, C terminal tensin like
, C-terminal tensin-like protein