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Synaptopodin is an actin-associated protein that may play a role in actin-based cell shape and motility. Zusätzlich bieten wir Ihnen Synaptopodin Kits (31) und Synaptopodin Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal SYNPO Primary Antibody für ICC, IHC - ABIN1742348
Tarabra, Giunti, Barutta, Salvidio, Burt, Deferrari, Gambino, Vergola, Pinach, Perin, Camussi, Gruden: Effect of the monocyte chemoattractant protein-1/CC chemokine receptor 2 system on nephrin expression in streptozotocin-treated mice and human cultured podocytes. in Diabetes 2009
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Cow (Bovine) Monoclonal SYNPO Primary Antibody für IHC (fro), IF - ABIN112223
Lechler, Wu, Bernhardt, Campean, Gastiger, Hackenbeck, Klanke, Weidemann, Warnecke, Amann, Engehausen, Willam, Eckardt, Rödel, Wiesener: The tumor gene survivin is highly expressed in adult renal tubular cells: implications for a pathophysiological role in the kidney. in The American journal of pathology 2007
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Human Polyclonal SYNPO Primary Antibody für IHC (p), WB - ABIN967124
GRAY: Electron microscopy of synaptic contacts on dendrite spines of the cerebral cortex. in Nature 1959
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Cow (Bovine) Monoclonal SYNPO Primary Antibody für IHC (fro), IF - ABIN112221
Câmpean, Karpe, Haas, Atalla, Peters, Rupprecht, Liebner, Acker, Plate, Amann: Angiopoietin 1 and 2 gene and protein expression is differentially regulated in acute anti-Thy1.1 glomerulonephritis. in American journal of physiology. Renal physiology 2008
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Human Polyclonal SYNPO Primary Antibody für IF (p), IHC (p) - ABIN701860
Zhang, Qu, Sun, Caruana, Bertram, Nikolic-Paterson, Li: Resolvin D1 protects podocytes in adriamycin-induced nephropathy through modulation of 14-3-3? acetylation. in PLoS ONE 2013
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Human Polyclonal SYNPO Primary Antibody für FACS - ABIN2559569
Jayachandran, Lugo, Heiling, Miller, Rule, Lieske: Extracellular vesicles in urine of women with but not without kidney stones manifest patterns similar to men: a case control study. in Biology of sex differences 2015
Rat (Rattus) Polyclonal SYNPO Primary Antibody für ICC, IHC - ABIN1742349
Wang, Dumoulin, Renner, Triller, Specht: The Role of Synaptopodin in Membrane Protein Diffusion in the Dendritic Spine Neck. in PLoS ONE 2016
Human Polyclonal SYNPO Primary Antibody für ICC, IF - ABIN4357202
Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013
Urine synaptopodin is associated with serum creatinine elevation in the patients with glomerulonephritis including diabetic kidney disease regardless of urine albumin (zeige ALB Antikörper) excretion. We suggest that the urine synaptopodin level can predict glomerular damage independently of the urine albumin (zeige ALB Antikörper) excretion.
SYNPO variants are involved in AMPA (zeige GRIA3 Antikörper) receptor trafficking and neuronal plasticity, which are associated with cognitive impairment and schizophrenia susceptibility.
This study identified and confirmed SYNPO protein changes within the postsynaptic density in schizophrenia
Case Report: immunohistologically detected synaptopodin upregulation in foamy podocytes in Fabry disease due to novel alpha-galactosidase A (zeige GLA Antikörper) mutation.
expression significantly down-regulated in presence of WT1 (zeige WT1 Antikörper) R458Q mutation
Shear stress induced actin binding proteins including SYNPO may play a critical role in endothelial wound healing.
These results suggested that the SA is an important component of the molecular machinery controlling the calcium-dependent accumulation of AMPA (zeige GRIA3 Antikörper)-receptors (AMPA (zeige GRIA3 Antikörper)-R) at excitatory synapses. [review]
The urinary mRNA profiles of synaptopodin, podocalyxin, CD2-AP, alpha-actin4, and podocin were found to increase with the progression of diabetic nephropathy.
Podocyte BK(Ca) channels are regulated by synaptopodin, Rho, and actin microfilaments.
Heterozygous mutations in the promoters of the ACTN4 (zeige ACTN4 Antikörper) and SYNPO genes are found in patients with idiopathic focal segmental glomerulosclerosis.
Results link synaptopodin (SP) with ryanodine receptors, in that ryanodine is able to convert short-term potentiation to long-term potentiation under our testing conditions only in ventral hippocampus, and only in the presence of SP in this region of the hippocampus.
miR-206 was up-regulated in Adriamycin nephropathy mice, which led to severe podocyte injury and inhibited the expression of WT1 and synaptopodin. In vitro, over expression of miR-206 induced WT1 and synaptopodin degradation and actin rearrangement, initiating a catastrophic collapse of the entire podocyte-stabilizing system.
WAVE1 (zeige WASF1 Antikörper) phosphorylation in podocytes. Synaptopodin is a well-characterized target of CsA (zeige HSPA9 Antikörper). WAVE1 (zeige WASF1 Antikörper) overexpression and synaptopodin knockdown experiments directly demonstrated that WAVE1 (zeige WASF1 Antikörper) expression is not dependent on synaptopodin expression, and vice versa
Inhibition of STAT3 (zeige STAT3 Antikörper) signaling in podocytes reduced synaptopodin levels in these cells.
synaptopodin has an essential, calcium store-related role in regulating synaptic plasticity in cultured hippocampal neurons
Our results identify synaptopodin as a substrate of PKA in hippocampal neurons and point to an essential role for synaptopodin in activity-dependent regulation of dendritic spine dynamics and synaptic plasticity in postnatal brain development.
Synaptopodin has an important role in homeostatic synaptic plasticity
Together, these results indicate that alpha-actinin (zeige ACTN1 Antikörper) and the actin cytoskeleton are important components of the cisternal organelle that are probably required to stabilize the AIS (zeige AR Antikörper).
Synpatopodin may play an important role in the changes of PSD-95 and NR1 protein levels and other synaptic alterations that are induced by corticosterone
HGF (zeige HGF Antikörper) protects podocytes from a loss of nephrin (zeige NPHS1 Antikörper), at least in part, through maintaining synaptopodin in nephritic mice with albuminuria.
Synaptopodin is an actin-associated protein that may play a role in actin-based cell shape and motility. The name synaptopodin derives from the protein's associations with postsynaptic densities and dendritic spines and with renal podocytes (Mundel et al., 1997