Synapsin III Proteine (SYN3)

SYN3 is a member of the synapsin gene family. Zusätzlich bieten wir Ihnen Synapsin III Antikörper (32) und Synapsin III Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SYN3 27204 Q8JZP2
SYN3 29130 O70441
SYN3 8224 O14994
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Showing 5 out of 5 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$7,759.50
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Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$7,759.50
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage
$785.40
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$405.71
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,663.00
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SYN3 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Rat (Rattus)

Human , ,
, ,

Weitere Proteine zu Synapsin III (SYN3) Interaktionspartnern

Mouse (Murine) Synapsin III (SYN3) Interaktionspartner

  1. This study demonstrated that synapsin 3 regulating GABA Release from Hippocampal Interneurons.

  2. These findings support a reciprocal modulatory interaction of alpha-syn and synapsin III in the regulation of dopamine neuron synaptic function.

  3. Behavioral and neurophysiological features of Syn3 knockout mice are characterized by observation of the development and progress of seizures from postnatal day 20 to 180.

  4. Analysis of cultured neurons from wild-type and Syn (zeige SYP Proteine) I,II,III-deficient triple knock-out (TKO (zeige MRPS12 Proteine)) mice shows that synaptic vesicles are severely dispersed in the absence of Syns.

  5. Mice lacking synapsin III show abnormalities in explicit memory and conditioned fear

  6. Collectively, our results demonstrate a novel role for synapsin III in regulating the proliferation of neural progenitor cells in the adult hippocampal dentate gyrus.

Human Synapsin III (SYN3) Interaktionspartner

  1. These findings contribute to previous work showing dysregulation of Synapsins, particularly SYN2 (zeige SYN2 Proteine), in mood disorders and improve our understanding of the regulatory mechanisms that precipitate these changes likely leading to the BD or MDD phenotype.

  2. Syn-3 may mimic Syn (zeige FYN Proteine)-1A in the ability to bind and modulate Cavs, but preferring Cav2.3 (zeige CACNA1E Proteine) to perhaps participate in triggering fusion of newcomer insulin (zeige INS Proteine) SGs (zeige FBN1 Proteine) during second-phase GSIS.

  3. These findings support a reciprocal modulatory interaction of alpha-syn and synapsin III in the regulation of dopamine neuron synaptic function.

  4. The variations of MnSOD (zeige SOD2 Proteine) (rs4880) and SYN (zeige FYN Proteine) III (rs3788470, rs3827336, rs5998557) were not major risk factors for PD among Chinese, at least in our study populations

  5. A significant difference was determined between attention deficit hyperactivity disorder and synapsin III gene -631 C>G polymorphism compared to the control group.

  6. Evidence is not in favor of a large effect of synapsin III gene in the pathogenesis of schizophrenia.

  7. A missense polymorphism, S470N, was identified in the synapsin III gene and appeared more frequently in individuals with schizophrenia. The site affected by the polymorphism, Ser470, was determined to be a substrate for mitogen-activated protein kinase (zeige MAPK1 Proteine).

  8. Supports a role for synapsin III in a subset of African American patients with schizophrenia.

  9. A trend towards significance was detected when the synapsin III -196A allele distribution was analyzed in Caucasian patients with schizophrenia and a cohort of subjects from the Czech Republic with bipolar disorder.

  10. No evidence that the synapsin III locus as a major susceptibility locus contributing to attention deficit hyperactivity disorder.

Synapsin III (SYN3) Protein Überblick

Protein Überblick

This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. The protein encoded by this gene shares the synapsin family domain model, with domains A, C, and E exhibiting the highest degree of conservation. The protein contains a unique domain J, located between domains C and E. Based on this gene's localization to 22q12.3, a possible schizophrenia susceptibility locus, and the established neurobiological roles of the synapsins, this family member may represent a candidate gene for schizophrenia. The TIMP3 gene is located within an intron of this gene and is transcribed in the opposite direction. Alternative splicing of this gene results in multiple splice variants that encode different isoforms.

Genbezeichner und Symbole assoziert mit Synapsin III Proteine (SYN3)

  • synapsin-3 (LOC100146694)
  • synapsin III (SYN3)
  • synapsin III L homeolog (syn3.L)
  • synapsin III (syn3)
  • synapsin III (Syn3)
  • SYN3 Protein
  • syn3-A Protein

Bezeichner auf Proteinebene für Synapsin III Proteine (SYN3)

synapsin III , synapsin 3a , synapsin-3-like , synapsin III isoform IIIa , synapsin 3 , synapsin IIIa , synapsin-3 , cN28H9.2 (synapsin III)

GENE ID SPEZIES
100146694 Equus caballus
458783 Pan troglodytes
100190606 Taeniopygia guttata
100410036 Callithrix jacchus
100594189 Nomascus leucogenys
373811 Xenopus laevis
100170548 Xenopus (Silurana) tropicalis
27204 Mus musculus
29130 Rattus norvegicus
8224 Homo sapiens
100328740 Oryctolagus cuniculus
481290 Canis lupus familiaris
100138309 Bos taurus
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