Succinate Dehydrogenase Complex Assembly Factor 2 Proteine (Sdhaf2)

Sdhaf2 encodes a mitochondrial protein needed for the flavination of a succinate dehydrogenase complex subunit required for activity of the complex. Zusätzlich bieten wir Ihnen Sdhaf2 Antikörper (10) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Sdhaf2 54949 Q9NX18
Sdhaf2 66072 Q8C6I2
Sdhaf2 361726 Q5RJQ7
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Showing 8 out of 9 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
Details
HOST_Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 11 bis 15 Tage
303,81 €
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
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Hefe Zebrafisch His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.145,88 €
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.180,79 €
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Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.180,79 €
Details
HOST_Escherichia coli (E. coli) Human His tag   1 mg Anmelden zum Anzeigen 6 bis 8 Tage
2.927,34 €
Details

Sdhaf2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine)

Rat (Rattus)

Weitere Proteine zu Succinate Dehydrogenase Complex Assembly Factor 2 (Sdhaf2) Interaktionspartnern

Human Succinate Dehydrogenase Complex Assembly Factor 2 (Sdhaf2) Interaktionspartner

  1. Loss of SDHAF2 gene is associated with paragangliomas.

  2. The SDHA (zeige SDHA Proteine), TMEM127, MAX, and SDHAF2 genes contribute to hereditary pheochromocytoma and paraganglioma.

  3. data show that SDHA (zeige SDHA Proteine) flavination is independent of SDHAF2 in breast cancer cells, employing an alternative mechanism.

  4. FAD (zeige BRCA2 Proteine) interacts noncovalently with SDHA (zeige SDHA Proteine) in the absence of SDH5

  5. Autosomal dominant susceptibility for Paraganglioma is modified by imprinting and mutations in the SDHAF2 gene cause Paragangliomas only when the mutation is inherited from father.

  6. Loss of heterozygosity was found in more than 50 % of the von Hippel-Lindau-associated pheochromocytomas, and was correlated with a significant decrease (p < 0.05) in both SDHAF2 and SDHD (zeige SDHD Proteine) mRNA expression, which may be suggestive of a pathogenic role.

  7. New mutation found in SDHAF2 gene in pheochromocytoma/paraganglioma patients.

  8. Data indicate that SDH5 is protected from mitochondrial LON (zeige LONP1 Proteine) (LONM)-mediated degradation in mitochondria by its stable interaction with SDHA (zeige SDHA Proteine), a state that is dysregulated in hereditary paraganglioma 2 (PGL2).

  9. Data indicate that succinate dehydrogenase (zeige SDHA Proteine) 5 (SDH5) functions as a critical protein in regulating epithelial-mesenchymal transition (EMT (zeige ITK Proteine)) by modulating the glycogen synthase kinase (GSK)-3beta-beta-catenin (zeige CTNNB1 Proteine) signaling pathway.

  10. Studies indicate that mutations in the mitochondrial complex II structural subunit genes SDHB (zeige SDHB Proteine), SDHC (zeige SDHC Proteine) and SDHD (zeige SDHD Proteine) and the regulatory subunit gene SDHAF2 in many paraganglioma families.

Sdhaf2 Protein Überblick

Protein Überblick

This gene encodes a mitochondrial protein needed for the flavination of a succinate dehydrogenase complex subunit required for activity of the complex. Mutations in this gene are associated with paraganglioma.

Genbezeichner und Symbole assoziert mit Sdhaf2

  • succinate dehydrogenase complex assembly factor 2 (SDHAF2)
  • succinate dehydrogenase complex assembly factor 2 (LOC100353725)
  • succinate dehydrogenase complex assembly factor 2 (Sdhaf2)
  • succinate dehydrogenase complex assembly factor 2 (sdhaf2)
  • 0610038F07Rik Protein
  • AA407634 Protein
  • AW049997 Protein
  • C11orf79 Protein
  • C14H11orf79 Protein
  • PGL2 Protein
  • RGD1309216 Protein
  • SDH5 Protein
  • wu:fj30e04 Protein
  • zgc:163000 Protein

Bezeichner auf Proteinebene für Sdhaf2

succinate dehydrogenase complex assembly factor 2 , succinate dehydrogenase assembly factor 2, mitochondrial , SDH assembly factor 2 , Protein EMI5 homolog, mitochondrial , succinate dehydrogenase subunit 5, mitochondrial , hSDH5

GENE ID SPEZIES
476065 Canis lupus familiaris
693401 Macaca mulatta
100173895 Pongo abelii
100353725 Oryctolagus cuniculus
54949 Homo sapiens
66072 Mus musculus
767983 Bos taurus
361726 Rattus norvegicus
569482 Danio rerio
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