anti-StAR-Related Lipid Transfer (START) Domain Containing 4 (STARD4) Antikörper

Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1\; MIM 184756) and by liver X receptors (e.g., LXRA\; MIM 602423). Zusätzlich bieten wir Ihnen STARD4 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
STARD4 134429 Q96DR4
STARD4 170459 Q99JV5
STARD4    
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Top anti-STARD4 Antikörper auf antikoerper-online.de

Showing 10 out of 28 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-STARD4 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:2500 Positive Control: HepG2 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB Formalin fixed and paraffin embedded human kidney tissue stained with STARD4 Antibody (N-term) Cat.-No AP54067PU-Nf ollowed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of STARD4 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. Western blot analysis in human placenta tissue lysates (35ug/lane) using STARD4 Antibody (N-term) Cat.-No AP54067PU-N. This demonstrates the STARD4 antibody detected the STARD4 protein (arrow). 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert IHC (p), WB STARD4 Antibody (N-term)  western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the STARD4 antibody detected the STARD4 protein (arrow). STARD4 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of STARD4 Antibody (N-term) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Maus Unkonjugiert WB Western Blot analysis of STARD4 expression in transfected 293T cell line by STARD4 MaxPab polyclonal antibody.<br><br>Lane 1: STARD4 transfected lysate(22.55 KDa).<br>Lane 2: Non-transfected lysate.<br> 50 μL Anmelden zum Anzeigen 11 bis 12 Tage
$430.00
Details
Human Kaninchen Unkonjugiert WB Western Blot: STARD4 Antibody [NBP1-68978] - HepG2 cell lysate, concentration 0.2-1 ug/ml. 100 μL Anmelden zum Anzeigen 8 bis 11 Tage
$447.56
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB   200 μL Anmelden zum Anzeigen 7 bis 9 Tage
$793.83
Details
Human Kaninchen Alkaline Phosphatase (AP) IHC, ELISA, WB   200 μL Anmelden zum Anzeigen 7 bis 9 Tage
$1,013.83
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Human Kaninchen APC IHC, ELISA, WB   200 μL Anmelden zum Anzeigen 7 bis 9 Tage
$1,013.83
Details
Human Kaninchen PE IHC, ELISA, WB   200 μL Anmelden zum Anzeigen 7 bis 9 Tage
$1,013.83
Details

STARD4 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human , ,
,

, , , , ,
Mouse (Murine)


Cow (Bovine)


Weitere Antikörper gegen STARD4 Interaktionspartner

Human StAR-Related Lipid Transfer (START) Domain Containing 4 (STARD4) Interaktionspartner

  1. This study shows that nonvesicular sterol transport mechanisms and STARD4 in particular account for a large fraction of sterol transport between the plasma membrane and the ERC (zeige ERC1 Antikörper).

  2. Studies show the 3 steroidogenic acute regulatory-related lipid transfer (START) domain proteins StarD4, StarD5 (zeige STARD5 Antikörper) and StarD6 (zeige STARD6 Antikörper) have a similar lipid binding pocket specific for sterols (cholesterol in particular), but differing regulation and localization.

  3. The data indicate a role for STARD4 in nonvesicular transport of cholesterol from the plasma membrane and the endocytic recycling compartment to the endoplasmic reticulum and perhaps other intracellular compartments as well.

  4. cholesterol transport mediated by STARD4 is an important component of the cholesterol homeostasis regulatory machinery

  5. Study provide strong evidence for StarD4 as a highly regulated, non-vesicular, directional, intracellular transporter of cholesterol which plays a key role in the maintenance of intracellular cholesterol homeostasis.

  6. StarD4-accelerated 7 alpha-OOH transfer to mitochondria resulted in greater susceptibility to free radical lipid peroxidation and loss of membrane potential than in a non-StarD4 control.

  7. StarD4 is regulated by sterols via SREBP-2 (zeige SREBF2 Antikörper), and StarD5 (zeige STARD5 Antikörper) is activated by ER stress cholesterol metabolism; they serve different functions

  8. Induction of STARD4 depended on both transcription factor ATF6 (zeige ATF6 Antikörper) and an ERSE-like element in its promoter.

  9. StarD4 plays an important role as a directional cholesterol transporter in the maintenance of cellular cholesterol homeostasis

Mouse (Murine) StAR-Related Lipid Transfer (START) Domain Containing 4 (STARD4) Interaktionspartner

  1. a model of STARD4 membrane interaction and sterol binding and release that requires dynamic movement of both the Omega1 loop and membrane insertion of the C-terminal alpha-helix.

  2. StARD4's role can largely be compensated for by other intracellular cholesterol transporters.

  3. StarD4 is regulated by sterols via SREBP-2 (zeige SREBF2 Antikörper), and StarD5 (zeige STARD5 Antikörper) is activated by ER stress cholesterol metabolism; they serve different functions

  4. StarD4 plays an important role as a directional cholesterol transporter in the maintenance of cellular cholesterol homeostasis

STARD4 Antigen-Profil

Protein Überblick

Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1\; MIM 184756) and by liver X receptors (e.g., LXRA\; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR\; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002

Genbezeichner und Symbole assoziert mit STARD4

  • StAR related lipid transfer domain containing 4 (STARD4) Antikörper
  • StAR-related lipid transfer (START) domain containing 4 (Stard4) Antikörper
  • 4632419C16Rik Antikörper
  • 9030213J02Rik Antikörper
  • AA517649 Antikörper
  • AW324468 Antikörper

Bezeichner auf Proteinebene für STARD4

START domain containing 4 sterol-regulated , START domain containing 4, sterol regulated , START domain-containing protein 4 , stAR-related lipid transfer protein 4

GENE ID SPEZIES
134429 Homo sapiens
170459 Mus musculus
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