anti-Spastic Paraplegia 21 (SPG21) Antikörper

The protein encoded by SPG21 was identified by a two-hybrid screen using CD4 as the bait. Zusätzlich bieten wir Ihnen SPG21 Proteine (18) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SPG21 51324 Q9NZD8
SPG21 27965 Q9CQC8
SPG21 300791 Q5XIC4
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Top anti-SPG21 Antikörper auf antikoerper-online.de

Showing 10 out of 30 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-SPG21 Antibody Titration: 1.0 ug/ml Positive Control: HepG2 Whole Cell 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-SPG21 Antibody Titration: 1.0 ug/ml Positive Control: 721_B Whole Cell SPG21 is supported by BioGPS gene expression data to be expressed in 721_B 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Cat Maus Unkonjugiert IHC (p), WB 0.5 mL Anmelden zum Anzeigen 7 bis 9 Tage
$764.50
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC (p), WB   50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$676.50
Details
Fledermaus Kaninchen Unkonjugiert IHC (p), WB   50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$676.50
Details
Human Maus Unkonjugiert ELISA Detection limit for recombinant GST tagged SPG21 is 0.3 ng/ml as a capture antibody. 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$430.00
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Western Blot: SPG21 Antibody [NBP1-89273] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Negative control (vector only transfected HEK293T lysate).Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY413881) Immunohistochemistry-Paraffin: SPG21 Antibody [NBP1-89273] - Staining of human kidney shows strong cytoplasmic positivity in cells in tubules. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$439.69
Details
Human Kaninchen Unkonjugiert ICC, IF, WB Immunocytochemistry/Immunofluorescence: SPG21 Antibody  - Staining of human cell line A549 shows localization to cytosol & vesicles. Western Blot: SPG21 Antibody  - Western blot analysis in human cell line RT-4, human cell line U-251 MG, human plasma, human liver tissue and human tonsil tissue. 100 μL Anmelden zum Anzeigen 10 bis 13 Tage
$439.69
Details
Human Maus Unkonjugiert ELISA, WB SPG21 polyclonal antibody (A01), Lot # 060516JCS1 Western Blot analysis of SPG21 expression in HL-60 . Western Blot detection against Immunogen (36.67 KDa) . 50 μL Anmelden zum Anzeigen 11 bis 12 Tage
$298.57
Details
Human Kaninchen Cy3 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details

SPG21 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Weitere Antikörper gegen SPG21 Interaktionspartner

Human Spastic Paraplegia 21 (SPG21) Interaktionspartner

  1. HBV X gene enhanced SPG21 gene promoter activity, SPG21 mRNA expression and SPG21 protein production in HepG2 cells in a dose-dependent manner.

  2. frameshift results in the premature termination of the encoded product, which is designated "maspardin" (Mast syndrome, spastic paraplegia, autosomal recessive with dementia)

  3. Data report that maspardin localizes prominently to cytoplasm as well as to membranes, possibly at trans-Golgi network/late endosomal compartments, and that maspardin interacts with the aldehyde dehydrogenase ALDH16A1 (zeige ALDH16A1 Antikörper).

Mouse (Murine) Spastic Paraplegia 21 (SPG21) Interaktionspartner

  1. Study showed that the loss of maspardin attenuates the growth, maturation, and axonal branching of cortical neurons to promote progressive neuronal dysfunction; impairment of sensory motor neurons in SPG21-/- mice; and that SPG21-/- cortical neurons failed to respond to EGF (zeige EGF Antikörper)-induced growth and maturation, which is confirmed by the attenuated expression of a subset of EGFR (zeige EGFR Antikörper) target genes

  2. Mast syndrome gene SPG21 in mice has a role in hind limb function and axon branching in cultured cortical neurons

SPG21 Antigen-Profil

Protein Überblick

The protein encoded by this gene was identified by a two-hybrid screen using CD4 as the bait. It binds to the hydrophobic C-terminal amino acids of CD4 which are involved in repression of T cell activation. The interaction with CD4 is mediated by the noncatalytic alpha/beta hydrolase fold domain of this protein. It is thus proposed that this gene product modulates the stimulatory activity of CD4. At least three different transcript variants encoding two different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit SPG21

  • maspardin pseudogene (LOC100345833) Antikörper
  • SPG21, maspardin (SPG21) Antikörper
  • spastic paraplegia 21 (autosomal recessive, Mast syndrome) (SPG21) Antikörper
  • SPG21, maspardin S homeolog (spg21.S) Antikörper
  • spastic paraplegia 21 (autosomal recessive, Mast syndrome) (spg21) Antikörper
  • SPG21, maspardin (Spg21) Antikörper
  • ACP33 Antikörper
  • BM-019 Antikörper
  • C78576 Antikörper
  • D9Wsu18e Antikörper
  • GL010 Antikörper
  • Maspardin Antikörper
  • MAST Antikörper
  • wu:fd07h02 Antikörper
  • zgc:73091 Antikörper

Bezeichner auf Proteinebene für SPG21

spastic paraplegia 21 , acid cluster protein 33 , maspardin , spastic paraplegia 21 autosomal recessive Mast syndrome protein homolog , spastic paraplegia 21 homolog , spastic paraplegia 21, maspardin (autosomal recessive, Mast syndrome)

GENE ID SPEZIES
100345833 Oryctolagus cuniculus
100358285 Oryctolagus cuniculus
51324 Homo sapiens
404069 Bos taurus
415526 Gallus gallus
487599 Canis lupus familiaris
100514084 Sus scrofa
734314 Xenopus laevis
100174603 Pongo abelii
406704 Danio rerio
27965 Mus musculus
300791 Rattus norvegicus
Ausgewählte Anbieter für anti-SPG21 (SPG21) Antikörper
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