anti-Solute Carrier Family 22 Member 5 (SLC22A5) Antikörper

Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. Zusätzlich bieten wir Ihnen SLC22A5 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SLC22A5 6584 O76082
SLC22A5 20520 Q9Z0E8
SLC22A5 29726 O70594
Direkt bei antikoerper-online bestellen
  • +49 (0)241 95 163 153
  • +49 (0)241 95 163 155
  • Online bestellen
  • orders@antikoerper-online.de

Top anti-SLC22A5 Antikörper auf antikoerper-online.de

Showing 10 out of 29 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-SLC22A5 Antibody Titration: 1.0 ug/ml Positive Control: Hela Whole Cell SLC22A5 is supported by BioGPS gene expression data to be expressed in HeLa 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Maus Kaninchen Unkonjugiert WB Anti-Solute carrier family 22 member 5 antibody, Western blotting Lane 1: Rat Kidney Tissue Lysate Lane 2: Rat Skeletal Muscles Tissue Lysate Lane 3: Mouse Liver Tissue Lysate Lane 4: HEPA Cell Lysate Lane 5: NIH3T3 Cell Lysate 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
298,57 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
Details
Human Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
Details
Human Kaninchen Unkonjugiert IF, IHC, WB Western blot analysis of extracts of various cell lines, using SLC22A5 antibody. 100 μL Anmelden zum Anzeigen 12 Days
261,90 €
Details
Human Kaninchen Unkonjugiert ELISA, WB   100 μL Anmelden zum Anzeigen 13 Days
154,33 €
Details
Maus Kaninchen Unkonjugiert IHC, WB Immunofluorescence analysis of MCF7 cell using SLC22A5 antibody. Blue: DAPI for nuclear staining. Western blot analysis of extracts of various cell lines, using SLC22A5 antibody. 100 μL Anmelden zum Anzeigen 11 bis 13 Tage
282,86 €
Details
Human Kaninchen Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Details
Human Kaninchen Unkonjugiert ELISA, WB   100 μL Anmelden zum Anzeigen 11 bis 14 Tage
1.281,59 €
Details

SLC22A5 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Human ,


Mouse (Murine)


Rat (Rattus)


Weitere Antikörper gegen SLC22A5 Interaktionspartner

Human Solute Carrier Family 22 Member 5 (SLC22A5) Interaktionspartner

  1. A homozygous stop variant in the SLC22A5 gene in a family with cardiomyopathy and sudden death history.

  2. Elucidation of GM-CSF (zeige CSF2 Antikörper) signaling demonstrates that the cytokine causes the activation of mTOR (zeige FRAP1 Antikörper) kinase, leading to the phosphorylation and activation of STAT3 (zeige STAT3 Antikörper), which, in turn, is responsible for OCTN2 transcription.

  3. dissociation of bound substrate from the transporter is rate limiting in establishing maximal rates of OCT2-mediated transport

  4. It is postulated that ZO-1 (zeige TJP1 Antikörper), when not phosphorylated by PKC (zeige PRRT2 Antikörper), keeps Octn2 in an active state, while elimination of this binding in DeltaPDZ mutant or after ZO-1 (zeige TJP1 Antikörper) phosphorylation leads to diminution of Octn2 activity.

  5. Results confirmed the diagnosis of eight patients with systemic primary carnitine deficiency (CDSP) on the gene level, including six mutations found in the solute carrier family 22 member 5 (SLC22A5) gene.

  6. Our results suggest that a common promoter haplotype of OCTN2 regulates the transcriptional rate of OCTN2 and influences the clinical course of CD.

  7. The local genotype influences methylation levels at SLC22A5 and ZPBP2 (zeige ZPBP2 Antikörper) promoters independently of the asthma status. Further studies are necessary to confirm the relationship between GSDMA (zeige GSDMA Antikörper)-ZPBP2 (zeige ZPBP2 Antikörper) and SLC22A5 methylation and asthma in females and males separately.

  8. The results of the current study demonstrated that -207C>G polymorphism of the SLC22A5 gene is not associated with male infertility.

  9. c.760C>T (p.R254X) mutation of the SLC22A5 gene is associated with the primary carnitine deficiency.

  10. Human OCTN2 expression is directly regulated by PPAR-alpha (zeige PPARA Antikörper).

Mouse (Murine) Solute Carrier Family 22 Member 5 (SLC22A5) Interaktionspartner

  1. There was increased apoptosis in gut (zeige GUSB Antikörper) samples from OCTN2(-/-) mice.

  2. Colon OCTN2 gene expression is up-regulated by peroxisome proliferator-activated receptor gamma (zeige PPARG Antikörper) in humans and mice and contributes to local and systemic carnitine homeostasis.

  3. OCTN2, a transporter that is thought to be responsible for the accumulation of L-carnitine in the epididymal lumen, is regulated in response to changes in tonicity.

  4. Mouse OCTN2 is a direct target gene of PPARalpha (zeige PPARA Antikörper) and transcriptional upregulation of OCTN2 by PPARalpha (zeige PPARA Antikörper) is likely mediated via PPRE1 in its first intron.

  5. acetyl-L-carnitine is transported from blood to brain extracellular fluid by OCTN2

  6. placental OCTN2 is obligatory for accumulation of carnitine in placenta & fetus, fatty acid beta-oxidation enzymes are expressed in placenta & reduced carnitine levels upregulate expression of short-chain L-3-hydroxyacyl CoA dehydrogenase (zeige HSD17B10 Antikörper) in placenta

  7. Novel OCTN2 in mouse pancreas.

  8. OCTN2 functions as a carnitine transporter between the epithelium and the lumen in distal corpus and cauda epididymides and provides a clue as to why obstructive azoospermia is induced in distal parts of epididymis.

  9. These findings indicate that OCTN2 is predominantly responsible for the uptake of carnitine from the apical surface of mouse small intestinal epithelial cells.

  10. PPAR alpha (zeige PPARA Antikörper)-activation results in enhanced carnitine biosynthesis and OCTN2-mediated hepatic carnitine accumulation

Cow (Bovine) Solute Carrier Family 22 Member 5 (SLC22A5) Interaktionspartner

  1. Dopamine transport across the olfactory and respiratory mucosae is partially mediated by organic cation transporters, including OCT-1 (zeige POU2F1 Antikörper) and OCT-2 (zeige SLC22A2 Antikörper). OCT-2 (zeige SLC22A2 Antikörper) was localized in the epithelial and submucosal regions of the nasal olfactory and respiratory mucosa

SLC22A5 Antigen-Profil

Protein Überblick

Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is a plasma integral membrane protein which functions both as an organic cation transporter and as a sodium-dependent high affinity carnitine transporter. The encoded protein is involved in the active cellular uptake of carnitine. Mutations in this gene are the cause of systemic primary carnitine deficiency (CDSP), an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation, and later in life by skeletal myopathy or cardiomyopathy.

Genbezeichner und Symbole assoziert mit SLC22A5

  • solute carrier family 22 (organic cation/carnitine transporter), member 5 (SLC22A5) Antikörper
  • solute carrier family 22 (organic cation transporter), member 5 (Slc22a5) Antikörper
  • solute carrier family 22 (organic cation transporter), member 5 (SLC22A5) Antikörper
  • solute carrier family 22 (organic cation transporter), member 5 (slc22a5) Antikörper
  • solute carrier family 22 (organic cation/carnitine transporter), member 5 (Slc22a5) Antikörper
  • organic cation/carnitine transporter 2 (2-Oct) Antikörper
  • ATOCT2 Antikörper
  • CDSP Antikörper
  • CT1 Antikörper
  • jvs Antikörper
  • Lstpl Antikörper
  • MGC68932 Antikörper
  • OCT2 Antikörper
  • Octn2 Antikörper
  • OCTN2VT Antikörper
  • organic cation/carnitine transporter 2 Antikörper
  • ORGANIC CATION TRANSPORTER 2 Antikörper
  • slc22a5 Antikörper
  • UST2r Antikörper
  • YUP8H12R.2 Antikörper
  • YUP8H12R_2 Antikörper

Bezeichner auf Proteinebene für SLC22A5

high-affinity sodium dependent carnitine cotransporter , organic cation/carnitine transporter 2 , solute carrier family 22 member 5 , high-affinity sodium-dependent carnitine cotransporter , juvenile visceral steatosis , solute carrier family 22 (organic cation/carnitine transporter), member 5 , solute carrier family 22 (organic cation transporter), member 5 , solute carrier family 22, member 5 , high-affinity carnitine transporter , integral membrane transport protein

GENE ID SPEZIES
6584 Homo sapiens
20520 Mus musculus
416328 Gallus gallus
541266 Bos taurus
100137218 Papio anubis
100358417 Oryctolagus cuniculus
380592 Xenopus laevis
29726 Rattus norvegicus
608146 Canis lupus familiaris
100072871 Equus caballus
100520422 Sus scrofa
844274 Arabidopsis thaliana
Ausgewählte Anbieter für anti-SLC22A5 (SLC22A5) Antikörper
Haben Sie etwas anderes gesucht?