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SLC16A10 is a member of a family of plasma membrane amino acid transporters that mediate the Na(+)-independent transport of aromatic amino acids across the plasma membrane.[supplied by OMIM, Apr 2004].. Zusätzlich bieten wir Ihnen und viele weitere Produktgruppen zu diesem Protein an.
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In the MCT10 modeled structure, N81 appeared to protrude into the putative trajectory of tryptophan.
the aim of this study was to examine if MCT8 (zeige MCT8 Antikörper) and MCT10 increase the availability of triiodothyronine for its nuclear receptor.
High TAT1 expression is associated with metastasis and recurrence in endometrial cancer.
Compared with the adult cerebral cortex, mRNAs encoding OATP1A2 (zeige SLCO1A2 Antikörper), OATP1C1 (zeige SLCO1C1 Antikörper), OATP3A1 (zeige SLCO3A1 Antikörper) variant 2, OATP4A1, LAT2 (zeige LAT2 Antikörper) and CD98 (zeige SLC3A2 Antikörper) were reduced in fetal cortex at different gestational ages, whilst mRNAs encoding MCT8 (zeige MCT8 Antikörper), MCT10, OATP3A1 (zeige SLCO3A1 Antikörper) variant 1 and LAT1 (zeige LAT Antikörper) were similar.
monocarboxylate transporter 10 facilitates bromoacetyl [(125)I] iodothyronine transport, but is not labeled by it
The strong expression of MCT10 and OATP1C1 (zeige SLCO1C1 Antikörper) in the human hypothalamus indicates a possible role in the regulation of the hypothalamus-pituitary-thyroid axis.
Increased MCT8 (zeige MCT8 Antikörper) and decreased MCT10 expression within placentae of pregnancies complicated by IUGR may contribute to aberrant development of the fetoplacental unit.
MCT10 is at least as active a thyroid hormone (zeige PTH Antikörper) transporter as hMCT8, and that both transporters facilitate iodothyronine uptake as well as efflux.
Mct10 participates in tissue-specific TH transport and also contributes to the generation of the unusual serum TH profile characteristic for Mct8 (zeige MCT8 Antikörper) deficiency
Data indicate that the uniporter TAT1 is required to equilibrate the concentration of aromatic amino acids across specific membranes.
The results suggest that Mct10 functions as a thyroid hormone (zeige PTH Antikörper) transporter in chondrocytes and can explain at least in part why Allan-Herndon-Dudley syndrome patients do not exhibit significant growth impairment.
expression of candidate thyroid hormone (zeige PTH Antikörper) transporters Lat1 (zeige SLC7A5 Antikörper), Mct8 (zeige MCT8 Antikörper), Mct10, and Oatp1c1 (zeige SLCO1C1 Antikörper) in mouse cochlear development
TAT1 is a basolateral epithelial transporter and can function as a net efflux pathway for aromatic amino acids. We propose that it may supply parallel exchangers with recycling uptake substrates that could drive the efflux of other amino acids.
the aromatic amino acid diffusion pathway TAT1 can control neutral amino acid efflux via neighboring exchanger LAT2 (zeige SLC7A8 Antikörper)-4F2hc (zeige SLC3A2 Antikörper), by recycling its aromatic influx substrates
SLC16A10 is a member of a family of plasma membrane amino acid transporters that mediate the Na(+)-independent transport of aromatic amino acids across the plasma membrane.
, T-type amino acid transporter 1
, aromatic amino acid transporter 1
, monocarboxylate transporter 10
, solute carrier family 16 (monocarboxylic acid transporters), member 10
, solute carrier family 16 member 10
, solute carrier family 16, member 10 (aromatic amino acid transporter)