anti-Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 7 (SLC12A7) Antikörper

Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. Zusätzlich bieten wir Ihnen SLC12A7 Proteine (7) und SLC12A7 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SLC12A7 10723 Q9Y666
SLC12A7 308069 Q5RK27
SLC12A7 20499 Q9WVL3
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Top anti-SLC12A7 Antikörper auf antikoerper-online.de

Showing 10 out of 75 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Ziege Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$242.88
Details
Human Maus Alexa Fluor 647 FACS Detection of KCC4/SLC12A7 in HEK293 Human Cell Line Transfected with Human SLC12A7 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with either (A) human SLC12A7 or (B) irrelevant transfectants and eGFP was stained with Mouse Anti-Human KCC4/SLC12A7 Alexa Fluor 647-conjugated Monoclonal Antibody. 25 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$205.85
Details
Human Kaninchen Unkonjugiert IHC (p), WB SLC12A7 Antibody (N-term)  western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the SLC12A7 antibody detected the SLC12A7 protein (arrow). SLC12A7 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SLC12A7 Antibody (N-term) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert WB WB Image Sample(30 μg of whole cell lysate) A:H1299 7.5% SDS PAGE antibody diluted at 1:500 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Human Maus Unkonjugiert CyTOF, FACS Detection of KCC4/SLC12A7 in HEK293 Human Cell Line Transfected with Human SLC12A7 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with either (A) human SLC12A7 or (B) human MRGPRF and eGFP was stained with Mouse Anti-Human KCC4/SLC12A7 Monoclonal Antibody. 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$304.75
Details
Hamster Ziege Unkonjugiert ELISA   100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
Details
Human Ziege Unkonjugiert ELISA   0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$373.75
Details
Maus Kaninchen Unkonjugiert EIA, IHC (fro), IF, WB   0.2 mL Anmelden zum Anzeigen 6 bis 8 Tage
$533.50
Details
Human Kaninchen Unkonjugiert WB   200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Maus Kaninchen Unkonjugiert ELISA, WB   50 μL Anmelden zum Anzeigen 7 bis 9 Tage
$654.50
Details

SLC12A7 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

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Am meisten referenzierte anti-SLC12A7 Antikörper

  1. Human Polyclonal SLC12A7 Primary Antibody für ELISA - ABIN449541 : Simard, Bergeron, Frenette-Cotton, Carpentier, Pelchat, Caron, Isenring: Homooligomeric and heterooligomeric associations between K+-Cl- cotransporter isoforms and between K+-Cl- and Na+-K+-Cl- cotransporters. in The Journal of biological chemistry 2007 (PubMed)

Weitere Antikörper gegen SLC12A7 Interaktionspartner

Human Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 7 (SLC12A7) Interaktionspartner

  1. SLC12A7 gene amplification and overexpression occurs frequently in adrenocortical carcinoma and may play a role in adrenocortical carcinoma tumorigenesis.

  2. The Wnk3 (zeige WNK3 Antikörper) protein isoforms have a similar effect on SLC12 cotransporters. NKCC1 (zeige SLC12A2 Antikörper)/2 and NCC (zeige SLC12A3 Antikörper) were inhibited, even in hypertonicity, while KCCs were activated, even in isotonic conditions.

  3. KCC3 (zeige SLC12A6 Antikörper) is the dominant isoform in erythrocytes, with variable expression of KCC1 (zeige SLC12A4 Antikörper) and KCC4 that could result in modulation of KCC activity

  4. Negative stain transmission electron microscopy and single particle analysis of KCC4 and the aquaporin-1 AQP1 (zeige AQP1 Antikörper) water channel (zeige AQP4 Antikörper), revealed the expected quaternary structures within homogeneous preparations, and thus correct protein folding and assembly.

  5. analysis of differences in large extracellular loop between the K(+)-Cl(-) cotransporters KCC2 (zeige SLC12A5 Antikörper) and KCC4

  6. KCC activation by IGF-1 (zeige IGF1 Antikörper) plays an important role in IGF-1 (zeige IGF1 Antikörper) signaling to promote growth and spread of gynecological cancers.

  7. Among patients with early-stage node-negative breast cancer, disease-free survival (DFS (zeige FST Antikörper)) and overall survival (OS) curves were significantly different based on IGF-1 (zeige IGF1 Antikörper) and KCC expression.

  8. KCC4 and H+,K+-ATPase (zeige ATP1A1 Antikörper) are the main machineries for basal HCl secretion in the apical canalicular membrane of the resting parietal cell. They also may contribute in part to massive acid secretion in the stimulated state.

  9. In the metastatic cancer tissues, KCC4 colocalizes with IGF-I (zeige IGF1 Antikörper) or EGF (zeige EGF Antikörper).

  10. Mice lacking SLC12A7 function suffer from deafness and renal metabolic acidosis. The phenotype suggests a function in inner ear potassium recycling. A function in the proton secreting alpha-intercalating cells of the kidney is shown.

Mouse (Murine) Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 7 (SLC12A7) Interaktionspartner

  1. During cell swelling PP1alpha (zeige PPP1CA Antikörper) and PP1gamma1 are involved in KCC4 regulation by WNK4 (zeige WNK4 Antikörper), but that the kinase acts upon these phosphatases to inhibit their activity.

  2. Data are consistent with a role for KCC4 in salt reabsorption of the thick ascending loop of Henle's loop and acid secretion of the collecting duct.

  3. We propose that glycosylation is essential for the surface expression, stabilization, and bioactivity of KCC4

  4. KCC3 (zeige SLC12A6 Antikörper) is the dominant isoform in erythrocytes, with variable expression of KCC1 (zeige SLC12A4 Antikörper) and KCC4 that could result in modulation of KCC activity

  5. Mice lacking SLC12A7 function suffer from deafness and renal metabolic acidosis. The phenotype suggests a function in inner ear potassium recycling. A function in the proton secreting alpha-intercalating cells of the kidney is shown.

  6. Ste20 (zeige STK24 Antikörper)-related proline-alanine-rich kinase (SPAK (zeige STK39 Antikörper)) and oxidative stress response 1 (OSR1 (zeige OSR1 Antikörper)) with the cotransporters KCC3 (zeige SLC12A6 Antikörper), NKCC1 (zeige SLC12A2 Antikörper), and NKCC2 (zeige SLC12A1 Antikörper) but not KCC1 (zeige SLC12A4 Antikörper) and KCC4

  7. all of the CCCs examined (NKCC1 (zeige SLC12A2 Antikörper), NKCC2 (zeige SLC12A1 Antikörper), KCC1 (zeige SLC12A4 Antikörper), KCC3 (zeige SLC12A6 Antikörper), and KCC4) can promote NH4(+) translocation, presumably through binding of the ion at the K(+) site

  8. KCC4 and H+,K+-ATPase (zeige ATP1A1 Antikörper) are the main machineries for basal HCl secretion in the apical canalicular membrane of the resting parietal cell. They also may contribute in part to massive acid secretion in the stimulated state.

SLC12A7 Antigen-Profil

Protein Überblick

Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification (By similarity).

Genbezeichner und Symbole assoziert mit SLC12A7

  • solute carrier family 12 (potassium/chloride transporters), member 7 (SLC12A7) Antikörper
  • solute carrier family 12 member 7 (SLC12A7) Antikörper
  • solute carrier family 12 member 7 (Slc12a7) Antikörper
  • solute carrier family 12, member 7 (Slc12a7) Antikörper
  • AA408796 Antikörper
  • D13Ertd261e Antikörper
  • Kcc4 Antikörper
  • Slc12a5 Antikörper
  • SLC12A7 Antikörper

Bezeichner auf Proteinebene für SLC12A7

solute carrier family 12 (potassium/chloride transporters), member 7 , K-Cl cotransporter 4 , electroneutral potassium-chloride cotransporter 4 , potassium/chloride transporter KCC4 , solute carrier family 12 member 7 , K-Cl cotransporter KCC4 , furosemide-sensitive KCl cotransporter 4 , potassium-chloride cotransporter

GENE ID SPEZIES
528038 Bos taurus
709581 Macaca mulatta
10723 Homo sapiens
308069 Rattus norvegicus
100008847 Oryctolagus cuniculus
20499 Mus musculus
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