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SGTA encodes a protein which is capable of interacting with the major nonstructural protein of parvovirus H-1 and 70-kDa heat shock cognate protein; however, its function is not known. Zusätzlich bieten wir Ihnen Small Glutamine-Rich Tetratricopeptide Repeat (TPR)-Containing, alpha Proteine (15) und viele weitere Produktgruppen zu diesem Protein an.
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study demonstrates a critical role of Hsc70 (zeige HSPA8 Antikörper) in SV40 endoplasmic reticulum-to-cytosol penetration and reveal how SGTA controls Hsc70 (zeige HSPA8 Antikörper) to impact this process
the binding of SGTA to Rpn13 enables specific polypeptides to escape proteasomal degradation and/or selectively modulates substrate degradation.
data suggest that SGTA regulates the cellular fate of a range of hydrophobic polypeptides should they become exposed to the cytosol.
Data show that molecular chaperone (zeige HSP90AA1 Antikörper) BAG6_ubiquitin-like domain (UBL) and ubiquitin-like 4A (zeige UBL4A Antikörper) UBL4A_UBL compete for the same binding site on N-terminal dimerisation domain of SGTA protein (SGTA_NT).
SGTA overexpression may be involved in the pathogenesis of breast cancer which might serve as a future target for novel treatment in breast cancer.
Our data suggest a role for SGTA at distinct steps in the chaperone-dependent modulation of androgen, glucocorticoid, and progesterone receptor (zeige PGR Antikörper) activity.
SGTA depletion decreased cyclin A (zeige CCNA2 Antikörper) and cyclin B levels.
A role of SGTA in Non-Hodgkin's lymphoma (NHL (zeige RTEL1 Antikörper)) cell proliferation, adhesion and drug resistance, and it may pave the way for a novel therapeutic approach for cell adhesion-mediated drug resistance in NHL (zeige RTEL1 Antikörper).
High expression of SGTA in esophageal squamous cell carcinoma correlates with proliferation and poor prognosis.
Univariate analysis showed that the low SGTB expression was associated with poor prognosis (P<0.001)
This gene encodes a protein which is capable of interacting with the major nonstructural protein of parvovirus H-1 and 70-kDa heat shock cognate protein\; however, its function is not known. Since this transcript is expressed ubiquitously in various tissues, this protein may serve a housekeeping function.
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
, small glutamine-rich tetratricopeptide
, small glutamine-rich tetratricopeptide repeat-containing protein beta
, small glutamine-rich tetratricopeptide repeat-containing protein alpha
, protein containing three tetratricopeptide repeats
, vpu-binding protein
, small glutamine-rich tetratricopeptide repeat (TPR) containing protein
, small glutamine-rich protein with tetratricopeptide repeats 1
, small glutamine-rich tetratricopeptide repeat (TPR) containing protein (SGT)