Sirtuin 7 Proteine (SIRT7)

SIRT7 encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Zusätzlich bieten wir Ihnen Sirtuin 7 Antikörper (172) und Sirtuin 7 Kits (13) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SIRT7 51547 Q9NRC8
SIRT7 209011 Q8BKJ9
SIRT7 303745  
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Showing 10 out of 15 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
395,77 €
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Anmelden zum Anzeigen 6 bis 8 Tage
628,57 €
Details
HOST_Escherichia coli (E. coli) Ratte His tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
731,43 €
Details
HOST_Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 7 bis 8 Tage
235,20 €
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
Details
Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.959,52 €
Details
HOST_Baculovirus infected Insect Cells Human His tag   5 μg Anmelden zum Anzeigen 6 bis 8 Tage
348,23 €
Details
HOST_Escherichia coli (E. coli) Human T7 tag,His tag   100 μg Anmelden zum Anzeigen 13 bis 17 Tage
655,24 €
Details

SIRT7 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , ,
, , ,
Mouse (Murine) ,

Rat (Rattus)

Weitere Proteine zu Sirtuin 7 (SIRT7) Interaktionspartnern

Human Sirtuin 7 (SIRT7) Interaktionspartner

  1. Data suggest that SIRT7 undergoes Lys (zeige LYZ Proteine)-63 polyubiquitination, later removed by USP7 (zeige USP7 Proteine) to repress enzymatic activity of SIRT7; USP7 (zeige USP7 Proteine) and SIRT7 regulate gluconeogenesis via expression of glucose-6-phosphatase catalytic subunit (G6PC (zeige G6PC Proteine)); SIRT7 targets G6PC (zeige G6PC Proteine) promoter through ELK4 (zeige ELK4 Proteine). (SIRT7 = sirtuin 7; USP7 (zeige USP7 Proteine) = ubiquitin specific peptidase 7 (zeige USP7 Proteine); G6PC (zeige G6PC Proteine) = glucose-6-phosphatase catalytic subunit (zeige G6PC Proteine); ELK4 (zeige ELK4 Proteine) = transcription factor ELK4 (zeige ELK4 Proteine))

  2. the decline in SIRT7 in lung fibroblasts has a profibrotic effect, which is mediated by changes in Smad3 (zeige SMAD3 Proteine) levels.

  3. SIRT7 inhibits TR4 degradation by deacetylation of DDB1.

  4. miR (zeige MLXIP Proteine)-152/SIRT7 axis plays a key role in the regulation of Human dental pulp stem cell senescence.

  5. our study suggests that SIRT7 functions as an oncogene (zeige RAB1A Proteine) in non-small cell lung cancer (NSCLC), and miR (zeige MLXIP Proteine)-3666 can target SIRT7 to inhibit NSCLC cell growth by promoting the pro-apoptotic signaling pathway

  6. SIRT7 trans-represses RPS7 (zeige RPS7 Proteine) gene in the presence of HBx protein.HBx enhances intracellular stability of SIRT7 protein.

  7. Data indicate that compared to non-neoplastic endometria (NNE (zeige ENO1 Proteine)), endometrial cancer (EC) showed SIRT7 mRNA overexpression, whereas SIRT1 (zeige SIRT1 Proteine), SIRT2 (zeige SIRT2 Proteine), SIRT4 (zeige SIRT4 Proteine) and SIRT5 (zeige SIRT5 Proteine) were underexpressed, and no significant differences were observed for SIRT3 (zeige SIRT3 Proteine) and SIRT6 (zeige SIRT6 Proteine).

  8. This study showed that SIRT7 can be activated by DNA to hydrolyze the acetyl group from lysine residues in vitro on histone peptides and histones in the chromatin context.

  9. Novel interactions of TPPII (zeige Tpp2 Proteine), p53 (zeige TP53 Proteine), and SIRT7 presented in this study might contribute to the knowledge of the regulatory effects of these proteins on apoptotic pathways and to the understanding mechanisms of aging and lifespan regulation.

  10. SIRT7 deacetylates U3-55k (zeige RRP9 Proteine), enhancing U3-55k (zeige RRP9 Proteine) binding to U3 snoRNA, which is a prerequisite for pre-rRNA processing.

Mouse (Murine) Sirtuin 7 (SIRT7) Interaktionspartner

  1. the decline in SIRT7 in lung fibroblasts has a profibrotic effect, which is mediated by changes in Smad3 (zeige SMAD3 Proteine) levels.

  2. SIRT7 inhibits TR4 degradation by deacetylation of DDB1.

  3. These results reveal a direct role for SIRT7 in double-strand break repair and establish a functional link between SIRT7-mediated histone H3 (zeige HIST3H3 Proteine) K18 (zeige KRT18 Proteine) deacetylation and the maintenance of genome integrity.

  4. miR (zeige MLXIP Proteine)-93 inhibits the metabolic target Sirt7, which we identified as a major driver of in vivo adipogenesis via induction of differentiation and maturation of early adipocyte precursors.

  5. The role of SIRT7 has emerged in protein synthesis, chromatin remodelling, cellular survival and lipid metabolism.

  6. SIRT7 stabilizes and activates the GABP alpha (zeige GABPA Proteine)/GABPbeta complex via deacetylation of GABPbeta1.

  7. SIRT7 controls hepatic lipid metabolism by regulating the ubiquitin-proteasome pathway.

  8. Study identifies SIRT7 as a cofactor of Myc (zeige MYC Proteine) for transcriptional repression and delineates a druggable regulatory branch of the ER stress response that prevents and reverts fatty liver disease.

  9. Mybbp1a (zeige MYBBP1A Proteine) is a novel negative regulator of Sirt7.

  10. SirT7 plays a dominant role in the growth inhibition of the P19 cells.

Sirtuin 7 (SIRT7) Protein Überblick

Protein Überblick

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined\; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.

Genbezeichner und Symbole assoziert mit Sirtuin 7 Proteine (SIRT7)

  • sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae) (SIRT7)
  • novel protein similar to vertebratesirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae) (SIRT7) (CH211-258L4.6)
  • phosphate cytidylyltransferase 2, ethanolamine (PCYT2)
  • sirtuin 7 (SIRT7)
  • sirtuin 7 (Sirt7)
  • LOC796135 Protein
  • SIR2L7 Protein
  • SIRT7 Protein

Bezeichner auf Proteinebene für Sirtuin 7 Proteine (SIRT7)

sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae) , sirtuin 7 , novel protein similar to vertebratesirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae) (SIRT7) , NAD-dependent deacetylase sirtuin-7 , sirtuin , NAD-dependent protein deacetylase sirtuin-7 , SIR2-like protein 7 , regulatory protein SIR2 homolog 7 , silent mating type information regulation 2, S.cerevisiae, homolog 7 , sir2-related protein type 7 , sirtuin type 7 , NAD-dependent deacetylase sirtuin 7

GENE ID SPEZIES
454975 Pan troglodytes
796135 Danio rerio
422093 Gallus gallus
51547 Homo sapiens
209011 Mus musculus
303745 Rattus norvegicus
483371 Canis lupus familiaris
100125965 Sus scrofa
505662 Bos taurus
Ausgewählte Anbieter für Sirtuin 7 Proteine (SIRT7)
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