Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
SIRT7 encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Zusätzlich bieten wir Ihnen Sirtuin 7 Antikörper (170) und Sirtuin 7 Proteine (15) und viele weitere Produktgruppen zu diesem Protein an.
Showing 6 out of 15 products:
Data indicate the role of SIRT7 in inhibiting SMAD4 (zeige SMAD4 ELISA Kits)-mediated breast cancer metastasis providing a possible therapeutic avenue.
Energy stress strengthens SIRT7-mediated effects on Akt (zeige AKT1 ELISA Kits) dephosphorylation.
The SIRT7 is mobilized from the nucleolus to the nucleoplasm and promotes DDB1 deacetylation, leading to decreased DDB1-CUL4 association and CRL4 activity.
Data suggest that SIRT7 undergoes Lys (zeige LYZ ELISA Kits)-63 polyubiquitination, later removed by USP7 (zeige USP7 ELISA Kits) to repress enzymatic activity of SIRT7; USP7 (zeige USP7 ELISA Kits) and SIRT7 regulate gluconeogenesis via expression of glucose-6-phosphatase catalytic subunit (G6PC (zeige G6PC ELISA Kits)); SIRT7 targets G6PC (zeige G6PC ELISA Kits) promoter through ELK4 (zeige ELK4 ELISA Kits). (SIRT7 = sirtuin 7; USP7 (zeige USP7 ELISA Kits) = ubiquitin specific peptidase 7 (zeige USP7 ELISA Kits); G6PC (zeige G6PC ELISA Kits) = glucose-6-phosphatase catalytic subunit (zeige G6PC ELISA Kits); ELK4 (zeige ELK4 ELISA Kits) = transcription factor ELK4 (zeige ELK4 ELISA Kits))
the decline in SIRT7 in lung fibroblasts has a profibrotic effect, which is mediated by changes in Smad3 (zeige SMAD3 ELISA Kits) levels.
SIRT7 inhibits TR4 degradation by deacetylation of DDB1.
miR (zeige MLXIP ELISA Kits)-152/SIRT7 axis plays a key role in the regulation of Human dental pulp stem cell senescence.
our study suggests that SIRT7 functions as an oncogene (zeige RAB1A ELISA Kits) in non-small cell lung cancer (NSCLC), and miR (zeige MLXIP ELISA Kits)-3666 can target SIRT7 to inhibit NSCLC cell growth by promoting the pro-apoptotic signaling pathway
SIRT7 trans-represses RPS7 (zeige RPS7 ELISA Kits) gene in the presence of HBx protein.HBx enhances intracellular stability of SIRT7 protein.
Data indicate that compared to non-neoplastic endometria (NNE (zeige ENO1 ELISA Kits)), endometrial cancer (EC) showed SIRT7 mRNA overexpression, whereas SIRT1 (zeige SIRT1 ELISA Kits), SIRT2 (zeige SIRT2 ELISA Kits), SIRT4 (zeige SIRT4 ELISA Kits) and SIRT5 (zeige SIRT5 ELISA Kits) were underexpressed, and no significant differences were observed for SIRT3 (zeige SIRT3 ELISA Kits) and SIRT6 (zeige SIRT6 ELISA Kits).
Histological analysis revealed that there is no apparent structural abnormality of the amygdala and hippocampus, which are regions involved in fear memory consolidation, in Sirt7 KO mice. Our results indicate that SIRT7 is involved in the consolidation of fear memory.
Data suggest that high-fat diet (HFD) alters regulation of expression of sirtuins (Sirt4 (zeige SIRT4 ELISA Kits) and Sirt7) and enzymes in NAD biosynthetic pathway (Tdo2 (zeige TDO2 ELISA Kits) and Nnmt (zeige NNMT ELISA Kits)); these alterations are more prominent in liver as compared to white adipose tissue or skeletal muscle; Tdo2 (zeige TDO2 ELISA Kits) and Nnmt (zeige NNMT ELISA Kits) may serve as markers of HFD consumption. (Tdo2 (zeige TDO2 ELISA Kits) = tryptophan 2,3-dioxygenase (zeige TDO2 ELISA Kits); Nnmt (zeige NNMT ELISA Kits) = nicotinamide N-methyltransferase (zeige NNMT ELISA Kits))
The Sirt7 mediates heterochromatin formation at rRNA genes through recruitment of DNA methyltransferase 1 (zeige DNMT1 ELISA Kits) and another member of the sirtuin (zeige SIRT1 ELISA Kits) family, Sirt1 (zeige SIRT1 ELISA Kits).
These results reveal a direct role for SIRT7 in double-strand break repair and establish a functional link between SIRT7-mediated histone H3 (zeige HIST3H3 ELISA Kits) K18 (zeige KRT18 ELISA Kits) deacetylation and the maintenance of genome integrity.
miR (zeige MLXIP ELISA Kits)-93 inhibits the metabolic target Sirt7, which we identified as a major driver of in vivo adipogenesis via induction of differentiation and maturation of early adipocyte precursors.
The role of SIRT7 has emerged in protein synthesis, chromatin remodelling, cellular survival and lipid metabolism.
SIRT7 stabilizes and activates the GABP alpha (zeige GABPA ELISA Kits)/GABPbeta complex via deacetylation of GABPbeta1.
SIRT7 controls hepatic lipid metabolism by regulating the ubiquitin-proteasome pathway.
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined\; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.
sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae)
, sirtuin 7
, novel protein similar to vertebratesirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae) (SIRT7)
, NAD-dependent deacetylase sirtuin-7
, NAD-dependent protein deacetylase sirtuin-7
, SIR2-like protein 7
, regulatory protein SIR2 homolog 7
, silent mating type information regulation 2, S.cerevisiae, homolog 7
, sir2-related protein type 7
, sirtuin type 7
, NAD-dependent deacetylase sirtuin 7