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SPPL2B Proteine

(Signal Peptide Peptidase-Like 2B (SPPL2B))
This gene encodes a member of the GXGD family of aspartic proteases. The GXGD proteases are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions. This enzyme localizes to endosomes, lysosomes, and the plasma membrane. It cleaves the transmembrane domain of tumor necrosis factor alpha to release the intracellular domain, which triggers cytokine expression in the innate and adaptive immunity pathways. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Häufig verwendete SPPL2B Proteine

Aliase für SPPL2B Proteine

signal peptide peptidase-like 2 (sppl2) Proteine
signal peptide peptidase like 2B (sppl2b) Proteine
signal peptide peptidase like 2B S homeolog (sppl2b.S) Proteine
signal peptide peptidase like 2B (SPPL2B) Proteine
signal peptide peptidase like 2B (Sppl2b) Proteine
signal peptide peptidase-like 2B (Sppl2b) Proteine
3110056O03Rik Proteine
AW550292 Proteine
IMP-4 Proteine
IMP4 Proteine
MGC147524 Proteine
PSH4 Proteine
PSL1 Proteine
RGD1308556 Proteine
SPPL2B Proteine
wu:fc16e01 Proteine
wu:fc85d12 Proteine
zgc:136525 Proteine
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