Sex Determining Region Y Proteine (SRY)

This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. Zusätzlich bieten wir Ihnen Sex Determining Region Y Antikörper (88) und Sex Determining Region Y Kits (19) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Human SRY SRY 6736 Q05066
Ratte SRY SRY 25221  
Maus SRY SRY 21674 Q05738
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Top Sex Determining Region Y Proteine auf antikoerper-online.de

Showing 10 out of 44 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,442.50
Details
Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$4,331.68
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$405.71
Details
Hefe Bos indicus His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,575.83
Details
Escherichia coli (E. coli) Maus His tag   50 μg Anmelden zum Anzeigen 11 Days
$341.00
Details
Hefe Maus His tag   50 μg Anmelden zum Anzeigen 8 bis 11 Tage
$341.00
Details
Hefe Akodon azarae His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,025.83
Details
Hefe Macaca fascicularis His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,035.00
Details
Hefe REACT_Eurasian badger His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,035.00
Details
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,240.33
Details

SRY Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
,
Rat (Rattus)

Mouse (Murine) ,

Am meisten referenzierte Sex Determining Region Y Proteine

  1. Human SRY Protein expressed in Wheat germ - ABIN1321373 : Holt, Zhang, Binia, Dixon, Vandiedonck, Cookson, Knight, Moffatt: Allele-specific transcription of the asthma-associated PHD finger protein 11 gene (PHF11) modulated by octamer-binding transcription factor 1 (Oct-1). in The Journal of allergy and clinical immunology 2011 (PubMed)

Weitere Proteine zu Sex Determining Region Y (SRY) Interaktionspartnern

Human Sex Determining Region Y (SRY) Interaktionspartner

  1. Activation of SRY and its downstream Sox9 (zeige SOX9 Proteine) and PDGFRalpha pathways are commonly involved in male hepatocarcinogenesis, which provides novel insights into gender disparity and sex-specific therapeutic strategies of hepatocellular carcinoma.

  2. a single-nucleotide polymorphism in the amelogenin (zeige AMELX Proteine) gene using amplified product-length polymorphisms in combination with sex-determining region Y analysis, is reported.

  3. Missense Mutation 224G>T (R75M) in SRY Coding Region is associated with 46, XY Gonadal Dysgenesis.

  4. Chemical proteasome inhibition restored native-like SRY expression and transcriptional activity in association with restored occupancy of a sex-specific enhancer element in principal downstream gene Sox9 (zeige SOX9 Proteine), demonstrating that the variant SRY exhibits essentially native activity on a per molecule basis.

  5. SRY is involved in the maintenance of cancer stem-like characteristics through OCT4 (zeige POU5F1 Proteine).

  6. The aim of this study was to compare two Y chromosome markers-SRY and DYS14-for their utility in the diagnosis of fetal gender

  7. These findings demonstrate that autosomal retention of SRY can be sub-microscopic and emphasize the importance of PCR and FISH in the genetic workup of the monosomic X male

  8. The SRY gene in plasma extracellular vesicles transferred to vascular endothelial cells may play an important role in the pathogenesis of atherosclerosis

  9. Results show that SRY could be expressed in tissues of Hirschsprung patients. It binds to the promoter of RET (zeige RET Proteine) gene by competing with SOX10 (zeige SOX10 Proteine) for its interaction with PAX3 (zeige PAX3 Proteine) and NKX2-1 (zeige NKX2-1 Proteine) repressing their transcriptional expression and RET's as well.

  10. High levels of SRY expression correlated with cancer progression and poor HCC (zeige FAM126A Proteine) patient survival. However, high SRY levels are not significantly correlated with HCC (zeige FAM126A Proteine) sex bias.

Cow (Bovine) Sex Determining Region Y (SRY) Interaktionspartner

  1. analysis of mtDNA control region sequences and SRY gene sequences indicated more contribution to the Yunnan cattle from B. indicus than from B. taurus

  2. New insights into SRY regulation through identification of 5' conserved sequence are reported.

Pig (Porcine) Sex Determining Region Y (SRY) Interaktionspartner

  1. The 4.6 Kb of pig SRY 5' flanking sequences supported reporter transgene expression within the male genital ridge but not within the neural crest.

  2. New insights into SRY regulation through identification of 5' conserved sequence are reported.

Horse (Equine) Sex Determining Region Y (SRY) Interaktionspartner

  1. This case represents the first report of an SRY negative XX-male sex reversal intersex phenotype, which is a potentially inherited condition, in an American saddlebred horse.

Rabbit Sex Determining Region Y (SRY) Interaktionspartner

Mouse (Murine) Sex Determining Region Y (SRY) Interaktionspartner

  1. Activation of SRY and its downstream Sox9 (zeige SOX9 Proteine) and PDGFRalpha pathways are commonly involved in male hepatocarcinogenesis, which provides novel insights into gender disparity and sex-specific therapeutic strategies of hepatocellular carcinoma.

  2. MAP2K6 (zeige MAP2K6 Proteine) functions in mouse testis determination, via positive effects on Sry, and a minor role for MAP2K3 (zeige MAP2K3 Proteine).

  3. our findings support that males lacking the testis determinant Sry can be fertile and reinforce the notion that Sry does not play a role in mature gonads.

  4. Variations in Usp9y and the number of CAG repeats in Sry are significantly associated with testes weight.

  5. Sry can be replaced by transgenic activation of its downstream target Sox9 (zeige SOX9 Proteine). This finding supports the existence of functional redundancy between the Y chromosome genes and their homologs encoded on other chromosomes.

  6. SRY binds to various ovarian differentiation genes and represses their activation through WNT (zeige WNT2 Proteine)/beta-catenin (zeige CTNNB1 Proteine) signaling.

  7. The SRY gene in plasma extracellular vesicles transferred to vascular endothelial cells may play an important role in the pathogenesis of atherosclerosis

  8. Studies indicate that in most of mammals, a single genetic trigger, the Y-linked gene Sry (sex determination region on Y chromosome), regulates testicular differentiation.

  9. disprove the hypothesis that the conserved HMG (zeige SSRP1 Proteine) box domain is the only functional domain of Sry, and highlight an evolutionary paradox whereby mouse Sry has evolved a novel bifunctional module to activate Sox9 (zeige SOX9 Proteine) directly

  10. this study demonstrates that live mouse progeny can also be generated by using germ cells from males with the Y chromosome contribution limited to only two genes, the testis determinant factor Sry and the spermatogonial proliferation factor Eif2s3y.

Sex Determining Region Y (SRY) Protein Überblick

Protein Überblick

This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome)\; translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome.

Genbezeichner und Symbole assoziert mit Sex Determining Region Y Proteine (SRY)

  • sex determining region Y (SRY)
  • sex determining region Y (Sry)
  • sex determining region of Chr Y (Sry)
  • SRXX1 Protein
  • SRXY1 Protein
  • SRY Protein
  • Sry1 Protein
  • Sry3BI Protein
  • SRYGENE Protein
  • Tdf Protein
  • Tdy Protein

Bezeichner auf Proteinebene für Sex Determining Region Y Proteine (SRY)

essential protein for sex determination in human males , sex-determining region Y protein , sex-determining region on Y , testis-determining factor on Y , HMG box transcription factor Sry1 , HMG box transcription factor Sry3BI , Testis determining locus , sex determining region of Chr Y , sex determining region on Y , testis-determining factor , sex determining factor Y , sex-determining region of the Y-chromosome , sex determining region Y protein , sex-determining protein , sex determining region Y , testis determining-Y , Sex-determining region Y protein , Testis-determining factor , sex determining region Y variant A , sex determining region Y variant B , testis determining factor , sex determining factor SRY , testis determining factor SRY

GENE ID SPEZIES
6736 Homo sapiens
25221 Rattus norvegicus
280931 Bos taurus
407740 Sus scrofa
449510 Pan troglodytes
493758 Felis catus
574155 Macaca mulatta
100033824 Equus caballus
100328958 Oryctolagus cuniculus
21674 Mus musculus
100529253 Ovis aries
108634533 Capra hircus
109555752 Bos indicus
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