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Sex Determining Region Y Proteine (SRY)

This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. Zusätzlich bieten wir Ihnen Sex Determining Region Y Antikörper (67) und Sex Determining Region Y Kits (14) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Maus SRY SRY 21674 Q05738
Human SRY SRY 6736 Q05066
Ratte SRY SRY 25221  
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Top Sex Determining Region Y Proteine auf antikoerper-online.de

Showing 10 out of 50 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
HOST_Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
Details
HOST_Escherichia coli (E. coli) Maus His tag   50 μg Anmelden zum Anzeigen 15 bis 16 Tage
324,76 €
Details
Hefe Maus His tag   50 μg Anmelden zum Anzeigen 12 bis 16 Tage
324,76 €
Details
Hefe Akodon azarae His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
1.929,36 €
Details
Hefe REACT_Eurasian badger His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
1.938,10 €
Details
Hefe Macaca fascicularis His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
1.938,10 €
Details
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.133,65 €
Details
Hefe Phocoenoides phocoena His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.355,40 €
Details

SRY Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine) ,

Human , ,
,
Rat (Rattus)

Am meisten referenzierte Sex Determining Region Y Proteine

  1. Human SRY Protein expressed in Wheat germ - ABIN1321373 : Holt, Zhang, Binia, Dixon, Vandiedonck, Cookson, Knight, Moffatt: Allele-specific transcription of the asthma-associated PHD finger protein 11 gene (PHF11) modulated by octamer-binding transcription factor 1 (Oct-1). in The Journal of allergy and clinical immunology 2011 (PubMed)

Weitere Proteine zu Sex Determining Region Y (SRY) Interaktionspartnern

Rabbit Sex Determining Region Y (SRY) Interaktionspartner

Pig (Porcine) Sex Determining Region Y (SRY) Interaktionspartner

  1. The 4.6 Kb of pig SRY 5' flanking sequences supported reporter transgene expression within the male genital ridge but not within the neural crest.

  2. New insights into SRY regulation through identification of 5' conserved sequence are reported.

Mouse (Murine) Sex Determining Region Y (SRY) Interaktionspartner

  1. our findings support that males lacking the testis determinant Sry can be fertile and reinforce the notion that Sry does not play a role in mature gonads.

  2. Variations in Usp9y and the number of CAG repeats in Sry are significantly associated with testes weight.

  3. Sry can be replaced by transgenic activation of its downstream target Sox9 (zeige SOX9 Proteine). This finding supports the existence of functional redundancy between the Y chromosome genes and their homologs encoded on other chromosomes.

  4. SRY binds to various ovarian differentiation genes and represses their activation through WNT (zeige WNT2 Proteine)/beta-catenin (zeige CTNNB1 Proteine) signaling.

  5. The SRY gene in plasma extracellular vesicles transferred to vascular endothelial cells may play an important role in the pathogenesis of atherosclerosis

  6. Studies indicate that in most of mammals, a single genetic trigger, the Y-linked gene Sry (sex determination region on Y chromosome), regulates testicular differentiation.

  7. disprove the hypothesis that the conserved HMG (zeige SSRP1 Proteine) box domain is the only functional domain of Sry, and highlight an evolutionary paradox whereby mouse Sry has evolved a novel bifunctional module to activate Sox9 (zeige SOX9 Proteine) directly

  8. this study demonstrates that live mouse progeny can also be generated by using germ cells from males with the Y chromosome contribution limited to only two genes, the testis determinant factor Sry and the spermatogonial proliferation factor Eif2s3y.

  9. Microsatellite-encoded domain in rodent Sry functions as a genetic capacitor to enable the rapid evolution of biological novelty.

  10. 70-kDa heat shock cognate protein hsc70 (zeige HSPA8 Proteine) mediates calmodulin (zeige Calm2 Proteine)-dependent nuclear import of the sex-determining factor SRY.

Human Sex Determining Region Y (SRY) Interaktionspartner

  1. Missense Mutation 224G>T (R75M) in SRY Coding Region is associated with 46, XY Gonadal Dysgenesis.

  2. Chemical proteasome inhibition restored native-like SRY expression and transcriptional activity in association with restored occupancy of a sex-specific enhancer element in principal downstream gene Sox9 (zeige SOX9 Proteine), demonstrating that the variant SRY exhibits essentially native activity on a per molecule basis.

  3. SRY is involved in the maintenance of cancer stem-like characteristics through OCT4 (zeige POU5F1 Proteine).

  4. The aim of this study was to compare two Y chromosome markers-SRY and DYS14-for their utility in the diagnosis of fetal gender

  5. These findings demonstrate that autosomal retention of SRY can be sub-microscopic and emphasize the importance of PCR and FISH in the genetic workup of the monosomic X male

  6. The SRY gene in plasma extracellular vesicles transferred to vascular endothelial cells may play an important role in the pathogenesis of atherosclerosis

  7. Results show that SRY could be expressed in tissues of Hirschsprung patients. It binds to the promoter of RET (zeige RET Proteine) gene by competing with SOX10 (zeige SOX10 Proteine) for its interaction with PAX3 (zeige PAX3 Proteine) and NKX2-1 (zeige NKX2-1 Proteine) repressing their transcriptional expression and RET's as well.

  8. High levels of SRY expression correlated with cancer progression and poor HCC (zeige FAM126A Proteine) patient survival. However, high SRY levels are not significantly correlated with HCC (zeige FAM126A Proteine) sex bias.

  9. Findings demonstrate that the folding, trafficking, and gene-regulatory function of testis-determining factor SRY requires an invariant aromatic "buttress" beneath its specific DNA-bending surface.

  10. Overall, these results indicated that the main mechanism of sex reversal are not associated with mutations in the coding regions of SOX9 (zeige SOX9 Proteine) and DAX1 (zeige NR0B1 Proteine) or copy number variations of SOX9 (zeige SOX9 Proteine), which is consistent with results of previous studies.

Cow (Bovine) Sex Determining Region Y (SRY) Interaktionspartner

  1. analysis of mtDNA control region sequences and SRY gene sequences indicated more contribution to the Yunnan cattle from B. indicus than from B. taurus

  2. New insights into SRY regulation through identification of 5' conserved sequence are reported.

Horse (Equine) Sex Determining Region Y (SRY) Interaktionspartner

  1. This case represents the first report of an SRY negative XX-male sex reversal intersex phenotype, which is a potentially inherited condition, in an American saddlebred horse.

Sex Determining Region Y (SRY) Protein Überblick

Protein Überblick

This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome)\; translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome.

Genbezeichner und Symbole assoziert mit Sex Determining Region Y Proteine (SRY)

  • sex determining region Y (SRY)
  • sex determining region of Chr Y (Sry)
  • sex determining region Y (Sry)
  • SRXX1 Protein
  • SRXY1 Protein
  • SRY Protein
  • Sry1 Protein
  • Sry3BI Protein
  • SRYGENE Protein
  • TDF Protein
  • TDY Protein

Bezeichner auf Proteinebene für Sex Determining Region Y Proteine (SRY)

sex determining region Y , sex-determining region Y protein , testis determining-Y , testis-determining factor , essential protein for sex determination in human males , sex-determining region on Y , testis-determining factor on Y , HMG box transcription factor Sry1 , HMG box transcription factor Sry3BI , Testis determining locus , sex determining region of Chr Y , sex determining region on Y , sex determining factor Y , sex-determining region of the Y-chromosome , sex determining region Y protein , sex-determining protein

GENE ID SPEZIES
100328958 Oryctolagus cuniculus
100625818 Sus scrofa
21674 Mus musculus
6736 Homo sapiens
25221 Rattus norvegicus
280931 Bos taurus
493758 Felis catus
100033824 Equus caballus
407740 Sus scrofa
100529253 Ovis aries
574155 Macaca mulatta
449510 Pan troglodytes
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