SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily D, Member 2 Proteine (SMARCD2)

The protein encoded by SMARCD2 is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. Zusätzlich bieten wir Ihnen SMARCD2 Antikörper (36) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SMARCD2 6603 Q92925
SMARCD2 83796 Q99JR8
SMARCD2 83833 O54772
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
3.347,14 €
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SMARCD2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine)

Rat (Rattus)

Weitere Proteine zu SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily D, Member 2 (SMARCD2) Interaktionspartnern

Human SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily D, Member 2 (SMARCD2) Interaktionspartner

  1. Data show that both CEBPE (zeige CEBPE Proteine) and SMARCD2 loss-of-function mutations identified in patients with neutrophil-specific granule deficiency (SGD (zeige SGCD Proteine)) abolish the interaction with SWI (zeige SMARCA1 Proteine)/SNF (zeige SNRPA Proteine) and secondary granule gene expression, thus providing a molecular basis for this disease.

  2. Defective expression of SMARCD2 (SWI (zeige SMARCA1 Proteine)/SNF (zeige SNRPA Proteine)-related, matrix-associated (zeige SMARCA5 Proteine), actin-dependent regulator of chromatin, subfamily D, member 2) leads to transcriptional and chromatin changes in acute myeloid leukemia (zeige BCL11A Proteine) (AML (zeige RUNX1 Proteine)) promyelocytic cells, suggesting SMARCD2 is a key factor controlling myelopoiesis and is a potential tumor suppressor in leukemia.

  3. the role of SMARCA4 and the two SWI/SNF subunits SMARCD2/BAF60B and DPF2/BAF45D in leukaemia, was investigated.

  4. the Rac (zeige AKT1 Proteine)- and Unkempt-dependent process leading to BAF60b ubiquitination takes place in the nuclear compartment

Mouse (Murine) SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily D, Member 2 (SMARCD2) Interaktionspartner

  1. the role of SMARCA4 and the two SWI/SNF subunits SMARCD2/BAF60B and DPF2/BAF45D in leukaemia, was investigated.

  2. the Rac (zeige AKT1 Proteine)- and Unkempt-dependent process leading to BAF60b ubiquitination takes place in the nuclear compartment

SMARCD2 Protein Überblick

Protein Überblick

The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and has sequence similarity to the yeast Swp73 protein. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit SMARCD2

  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 (SMARCD2)
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 (smarcd2)
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 (Smarcd2)
  • AW322457 Protein
  • BAF60b Protein
  • CRACD2 Protein
  • pro2451 Protein
  • Rsc6p Protein
  • SMARCD2 Protein

Bezeichner auf Proteinebene für SMARCD2

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 , SWI/SNF-related matrix-associated actin-dependent regulator of chromatin d2 , 60 kDa BRG-1/Brm-associated factor subunit B , BRG1-associated factor 60B , SWI/SNF complex 60 kDa subunit B , SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 , Swp73-like protein , chromatin remodeling complex BAF60B subunit , mammalian chromatin remodeling complex BRG1-associated factor 60B

GENE ID SPEZIES
454776 Pan troglodytes
734143 Xenopus (Silurana) tropicalis
100539844 Meleagris gallopavo
6603 Homo sapiens
564317 Danio rerio
447634 Xenopus laevis
428275 Gallus gallus
480477 Canis lupus familiaris
789613 Bos taurus
83796 Mus musculus
83833 Rattus norvegicus
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