anti-SH2B Adaptor Protein 1 (SH2B1) Antikörper

SH2B1 encodes a member of the SH2-domain containing mediators family. Zusätzlich bieten wir Ihnen SH2B Adaptor Protein 1 Proteine (6) und SH2B Adaptor Protein 1 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SH2B1 25970 Q9NRF2
SH2B1 20399 Q91ZM2
SH2B1 89817 Q62985
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Top anti-SH2B Adaptor Protein 1 Antikörper auf antikoerper-online.de

Showing 10 out of 65 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Ziege Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$242.88
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis using SH2B1 Antibody (C-term) Cat.-No AP53895PU-N in 293 cell line lysates (35ug/lane).This demonstrates the SH2B1 antibody detected the SH2B1 protein (arrow). 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Maus Unkonjugiert IF, WB Western blot analysis of SH2-B in SW13 lysate. Lane 1: 1:500, lane 2: 1:1000, lane 3: 1:2000 dilution of SH2-B. HeLa 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
$168.74
Details
Fledermaus Kaninchen Unkonjugiert IHC (p), WB Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$676.50
Details
Human Kaninchen Unkonjugiert WB SH2B1 Antibody (C-term)  western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the SH2B1 antibody detected the SH2B1 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert ICC, IF, WB Immunocytochemistry/Immunofluorescence: SH2B1 Antibody [NBP2-43830] - Analysis (Olympus FV10i) of paraformaldehyde-fixed A431, using SH2B antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled (Red) at 1:2000. Western Blot: SH2B1 Antibody  - Non-transfected (-) and transfected (+) C2C12 whole cell extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with SH2B antibody diluted at 1:2000. 0.1 mL Anmelden zum Anzeigen 8 bis 11 Tage
$514.63
Details
Rind (Kuh) Ziege Unkonjugiert ELISA   0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$373.75
Details
Fledermaus Ziege Unkonjugiert WB   100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$1,035.83
Details
Human Maus Unkonjugiert WB Western Blot analysis of SH2B1 expression in transfected 293T cell line by SH2B1 monoclonal antibody (M01), clone 2B9. Lane 1: SH2B1 transfected lysate(52.917 KDa). Lane 2: Non-transfected lysate. Detection limit for recombinant GST tagged SH2B is approximately 0.03 ng/mL as a capture antibody. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$450.00
Details

SH2B1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-SH2B Adaptor Protein 1 Antikörper

  1. Human Monoclonal SH2B1 Primary Antibody für IF, WB - ABIN968576 : Rothenberg: Bioethics commission to review gene patenting. in Bio/technology (Nature Publishing Company) 1998 (PubMed)
    Show all 7 Pubmed References

  2. Cow (Bovine) Polyclonal SH2B1 Primary Antibody für ELISA - ABIN268802 : OBrien, OShea, Carter-Su: SH2-B family members differentially regulate JAK family tyrosine kinases. in The Journal of biological chemistry 2002 (PubMed)

Weitere Antikörper gegen SH2B Adaptor Protein 1 Interaktionspartner

Human SH2B Adaptor Protein 1 (SH2B1) Interaktionspartner

  1. Chromosome microarray analysis was performed on both twins and their parents. An identical 244 kb microdeletion on 16p11.2 including 9 Refseq genes, including SH2B1, was identified in the twins.

  2. SH2B1 fine-tunes global-local chromatin states.

  3. SH2B1 and RABEP1 (zeige RABEP1 Antikörper) genetic variants are associated with worsening of LDL and glucose parameters in patients treated with psychotropic drugs

  4. SH2B1 polymorphisms are associated with HbA1c, largely independent of BMI, in European American young adults.

  5. Results identified SH2B as a functional target of miR (zeige MLXIP Antikörper)-361 which down-regulation suppresses lung cancer progression and metastasis through regulation of SH2B1.

  6. that SH2B1 is a key positive mediator of pathological cardiac hypertrophy

  7. Mutation analysis has demonstrated that variation in the SH2B1 gene is frequent in both lean and obese groups, with distinctive variations being present on either side of the weight spectrum.

  8. The rs7359397 (SH2B1) was associated with the body weight, body mass index, and truncal fat mass reduction.

  9. 4 novel variants in SH2B1 were identified in individuals with obesity and insulin (zeige INS Antikörper) resistance.

  10. This study highlighted the importance of two candidate genes, SH2B1 and FAIM2 (zeige FAIM2 Antikörper), in the risk of overweight/obesity.

Mouse (Murine) SH2B Adaptor Protein 1 (SH2B1) Interaktionspartner

  1. data identify SH2B1 as a major regulator of IRS2 (zeige IRS2 Antikörper) stability, demonstrate a novel feedback mechanism linking mTORC1 signaling with IRS2 (zeige IRS2 Antikörper), and identify 4E-BP2 (zeige EIF4EBP2 Antikörper) as a major regulator of proliferation and survival of beta-cells.

  2. that SH2B1 is a key positive mediator of pathological cardiac hypertrophy

  3. SH2B1 in pancreatic beta-cells promotes insulin (zeige INS Antikörper) synthesis and secretion at least in part by enhancing activation of JAK2 (zeige JAK2 Antikörper) and/or Pdx1 (zeige PDX1 Antikörper) pathways in response to hormonal and nutritional signals.

  4. hepatic SH2B1 is not required for the maintenance of normal insulin (zeige INS Antikörper) sensitivity and glucose metabolism; however, it regulates liver triacylglycerol synthesis, lipolysis, and VLDL secretion.

  5. These data indicate that SH2B1 in beta-cells is an important prosurvival and proproliferative protein and promotes compensatory beta-cell expansion in the insulin (zeige INS Antikörper)-resistant state and in response to beta-cell stress.

  6. SH2B1 is responsive to erythropoietin (zeige EPO Antikörper) stimulation and becomes phosphorylated

  7. Leptin (zeige LEP Antikörper)-stimulated activation of hypothalamic JAK2 (zeige JAK2 Antikörper) and phosphorylation of hyphothalamic IRS2 (zeige IRS2 Antikörper) were significantly impaired in SH2B1(-/-) mice.

  8. Mutations in the SH2 (zeige MYO15 Antikörper) domain of SH2B1 may increase the susceptibility to obesity and type 2 diabetes in a dominant-negative manner.

  9. Genetic deletion of SH2B1 also resulted in growth retardation, obesity, and type 2 diabetes in mice; surprisingly, life span and oxidative resistance were reduced in SH2B1 null mice.

  10. These results suggest that SH2-Bbeta regulation of Akt partly participates in the NGF-mediated development of allergic airway challenge.

SH2B Adaptor Protein 1 (SH2B1) Antigen-Profil

Protein Überblick

This gene encodes a member of the SH2-domain containing mediators family. The encoded protein mediates activation of various kinases and may function in cytokine and growth factor receptor signaling and cellular transformation. Alternatively spliced transcript variants have been described.

Genbezeichner und Symbole assoziert mit SH2B1

  • SH2B adaptor protein 1 (SH2B1) Antikörper
  • SH2B adaptor protein 1 (sh2b1) Antikörper
  • SH2B adaptor protein 1 (Sh2b1) Antikörper
  • AI425885 Antikörper
  • C530001K22Rik Antikörper
  • Irip Antikörper
  • mKIAA1299 Antikörper
  • PSM Antikörper
  • Sh2-b Antikörper
  • SH2-Bb Antikörper
  • Sh2b Antikörper
  • SH2B3 Antikörper
  • Sh2bpsm1 Antikörper
  • zgc:158474 Antikörper

Bezeichner auf Proteinebene für SH2B1

SH2B adapter protein 1 , SH2B adaptor protein 1 , SH2B adapter protein 1-like , SH2 domain-containing protein 1B , SH2 domain-containing putative adapter SH2-B , SH2-B signaling protein , pro-rich, PH and SH2 domain-containing signaling mediator , PSM , SH2-B PH domain containing signaling mediator 1 , SH2-B PH domain-containing signaling mediator 1 , fceRI gamma-chain-interacting protein SH2-B

GENE ID SPEZIES
506066 Bos taurus
558152 Danio rerio
708160 Macaca mulatta
100064371 Equus caballus
100385268 Callithrix jacchus
100470297 Ailuropoda melanoleuca
100587926 Nomascus leucogenys
25970 Homo sapiens
20399 Mus musculus
89817 Rattus norvegicus
612792 Canis lupus familiaris
100516788 Sus scrofa
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