anti-Ring Finger Protein 139 (RNF139) Antikörper

The protein encoded by RNF139 is a multi-membrane spanning protein containing a RING-H2 finger. Zusätzlich bieten wir Ihnen Ring Finger Protein 139 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
RNF139 11236 Q8WU17
RNF139 75841 Q7TMV1
RNF139 315000  
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Top anti-Ring Finger Protein 139 Antikörper auf antikoerper-online.de

Showing 10 out of 57 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-RNF139 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>MCF7 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Maus Unkonjugiert WB RNF139 monoclonal antibody (M01), clone 3D10 Western Blot analysis of RNF139 expression in HepG2 on formalin-fixed paraffin-embedded human tonsil (antibody concentration 3 µg/mL). 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$450.00
Details
Fledermaus Kaninchen Unkonjugiert IHC (p), WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$676.50
Details
Hund Ziege Unkonjugiert EIA, IHC (p), WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$375.38
Details
Human Maus Unkonjugiert IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to RNF139 on formalin-fixed paraffin-embedded human tonsil. [antibody concentration 3 ug/ml] RNF139 monoclonal antibody (M01), clone 3D10 Western Blot analysis of RNF139 expression in HepG2 . 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$430.00
Details
Human Maus Unkonjugiert ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL Anmelden zum Anzeigen 11 bis 12 Tage
$298.57
Details
Human Ziege Unkonjugiert IHC, ELISA, WB (1µg/ml) staining of Human Skeletal Muscle lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$326.89
Details
Human Ziege Unkonjugiert IHC (p), ELISA, WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$451.00
Details
Human Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$433.13
Details
Human Maus Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$537.17
Details

RNF139 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Ring Finger Protein 139 Antikörper

  1. Human Polyclonal RNF139 Primary Antibody für ELISA, WB - ABIN564886 : Brauweiler, Lorick, Lee, Tsai, Chan, Weissman, Drabkin, Gemmill: RING-dependent tumor suppression and G2/M arrest induced by the TRC8 hereditary kidney cancer gene. in Oncogene 2007 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal RNF139 Primary Antibody für IHC (p), ELISA - ABIN564887 : Adams, Simms, Abdelhamed, Dawe, Szymanska, Logan, Wheway, Pitt, Gull, Knowles, Blair, Cross, Sayer, Johnson: A meckelin-filamin A interaction mediates ciliogenesis. in Human molecular genetics 2012 (PubMed)

Weitere Antikörper gegen Ring Finger Protein 139 Interaktionspartner

Human Ring Finger Protein 139 (RNF139) Interaktionspartner

  1. interaction with Bag1 (zeige BAG1 Antikörper) then shifts hERG (zeige KCNH2 Antikörper) degradation to the membrane-anchored E3 ligase TRC8 and its E2-conjugating enzyme Ube2g2 (zeige UBE2G2 Antikörper), as determined by siRNA screening

  2. TRC8 and TMEM129 are endoplasmic reticulum-associated degradation ubiquitin E3 ligases for viral and cellular targeting of MHC class I. (Review)

  3. TRC8 suppresses tumorigenesis through targeting heme oxygenase-1 (zeige HMOX1 Antikörper) for ubiquitination and degradation.

  4. TRC8 function may provide a regulatory link between the lipid and protein biosynthetic pathways.

  5. TRC8 modulation of sterol response element binding protein activity comprises a novel regulatory link between growth control and the cholesterol/lipid homeostasis pathway.

  6. The presence of diploid and tetraploid tumor cells with and without TRC8 deletions on the nontranslocated chromosome suggest that loss of the remaining normal allele of TRC8 may contribute to tumor development at later stages.

  7. TRC8 is a novel sterol-sensing endoplasmic reticulum membrane protein (zeige SLC39A6 Antikörper) that hinders SREBP-2 (zeige SREBF2 Antikörper) processing through interaction with SREBP-2 (zeige SREBF2 Antikörper) and SCAP (zeige SH2D2A Antikörper), regulating its own turnover rate by means of its E3 ubiquitin ligase (zeige MUL1 Antikörper) activity

  8. Data show that the TRC8 E3 ligase is required for MHC I dislocation from the ER and identify a new complex associated with mammalian ERAD.

Ring Finger Protein 139 (RNF139) Antigen-Profil

Protein Überblick

The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.

Genbezeichner und Symbole assoziert mit RNF139

  • ring finger protein 139 (RNF139) Antikörper
  • ring finger protein 139 (Rnf139) Antikörper
  • ring finger protein 139 (rnf139) Antikörper
  • ring finger protein 139 S homeolog (rnf139.S) Antikörper
  • 4930555P18Rik Antikörper
  • HRCA1 Antikörper
  • RCA1 Antikörper
  • rnf139 Antikörper
  • TRC8 Antikörper
  • zgc:175173 Antikörper

Bezeichner auf Proteinebene für RNF139

E3 ubiquitin-protein ligase RNF139 , multiple membrane spanning receptor TRC8 , patched related protein translocated in renal cancer , translocation in renal carcinoma on chromosome 8 protein , RING finger protein 139 , ring finger protein 139 S homeolog

GENE ID SPEZIES
11236 Homo sapiens
75841 Mus musculus
315000 Rattus norvegicus
420338 Gallus gallus
609422 Canis lupus familiaris
100067392 Equus caballus
100156613 Sus scrofa
788471 Bos taurus
100447707 Pongo abelii
100734055 Cavia porcellus
100357210 Oryctolagus cuniculus
100144552 Danio rerio
444792 Xenopus laevis
Ausgewählte Anbieter für anti-Ring Finger Protein 139 (RNF139) Antikörper
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