Ring Finger Protein 135 Proteine (RNF135)

The protein encoded by RNF135 contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. Zusätzlich bieten wir Ihnen Ring Finger Protein 135 Antikörper (47) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
RNF135 84282 Q8IUD6
RNF135 71956 Q9CWS1
RNF135 303350 Q5M929
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Showing 5 out of 6 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
Details
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
3.003,17 €
Details

RNF135 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Rat (Rattus)

Weitere Proteine zu Ring Finger Protein 135 (RNF135) Interaktionspartnern

Human Ring Finger Protein 135 (RNF135) Interaktionspartner

  1. In-depth analysis of population-differentiated regions indicated that the coding gene, RNF135, represented a trans-regulation hotspot via cis (zeige CISH Proteine)-regulation by the population-specific variants in the region of selective sweep.

  2. findings demonstrate the biological effects of RNF135 in glioblastoma cell proliferation, migration and cell cycle, and its role in the progression of glioblastoma may be associated with the ERK (zeige EPHB2 Proteine) signal transduction pathway.

  3. Data showed that the presence of the RNF135 K115 variant in the genotype of patients with autism was statistically significant.

  4. Riplet-mediated K63-linked polyubiquitination released RIG-I (zeige DDX58 Proteine) RD autorepression, which allowed the access of positive factors to the RIG-I (zeige DDX58 Proteine) protein.

  5. REUL is an E3 ubiquitin ligase (zeige MUL1 Proteine) of RIG-I (zeige DDX58 Proteine) and specifically stimulates RIG-I (zeige DDX58 Proteine)-mediated innate antiviral activity

  6. These data identify RNF135 as causative of a new overgrowth syndrome and demonstrate that RNF135 haploinsufficiency contributes to the phenotype of NF1 (zeige NF1 Proteine) microdeletion cases.

  7. identify an alternative factor, Riplet/RNF135, that promotes RIG-I (zeige DDX58 Proteine) activation independent of TRIM25 (zeige TRIM25 Proteine)

  8. RNF135 mutations are not present in patients with Sotos syndrome-like features.

Mouse (Murine) Ring Finger Protein 135 (RNF135) Interaktionspartner

  1. Riplet-mediated K63-linked polyubiquitination released RIG-I (zeige DDX58 Proteine) RD autorepression, which allowed the access of positive factors to the RIG-I (zeige DDX58 Proteine) protein.

  2. Riplet is essential for regulating RIG-I (zeige DDX58 Proteine)-mediated innate immune response against RNA virus infection in vivo.

Ring Finger Protein 135 (RNF135) Protein Überblick

Protein Überblick

The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. This gene is located in a chromosomal region known to be frequently deleted in patients with neurofibromatosis. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Genbezeichner und Symbole assoziert mit RNF135

  • ring finger protein 135 (RNF135)
  • ring finger protein 135 (Rnf135)
  • 0610037N03Rik Protein
  • 2410006N06Rik Protein
  • LRRGT00184 Protein
  • MMFD Protein
  • REUL Protein
  • Riplet Protein

Bezeichner auf Proteinebene für RNF135

E3 ubiquitin-protein ligase RNF135 , RIG-I E3 ubiquitin ligase , Riplet , U 2-3-0

GENE ID SPEZIES
84282 Homo sapiens
480614 Canis lupus familiaris
511125 Bos taurus
71956 Mus musculus
303350 Rattus norvegicus
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