Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs Proteine (RECK)

The protein encoded by RECK is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. Zusätzlich bieten wir Ihnen RECK Antikörper (81) und RECK Kits (8) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
RECK 8434 O95980
RECK 53614 Q9Z0J1
Ratte RECK RECK 313488  
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 66 Days
10.536,00 €
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 66 Days
10.536,00 €
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HOST_Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 7 bis 8 Tage
235,20 €
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RECK Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine)

Weitere Proteine zu Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK) Interaktionspartnern

Human Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK) Interaktionspartner

  1. Reversion-inducing, cysteine-rich protein (zeige SPARC Proteine) with kazal motifs (RECK) was identified as the direct and functional target of miR (zeige MLXIP Proteine)-92b in osteosarcoma

  2. RECK expression in uterine leiomyoma is negatively regulated by miR (zeige MLXIP Proteine)-15b.

  3. RECK could regulate the expressions of MMP-2 (zeige MMP2 Proteine), 9 and MT1-MMP (zeige MMP14 Proteine) as a cell surface-signaling molecule. Authors propose that RECK may play an important role in regulating MMPs in the ECM (zeige MMRN1 Proteine) degradation of periodontal diseases.

  4. Low expression of RECK is associated with oral cancer.

  5. RECK Gene Promoter rs10814325 Polymorphism is associated with metastasis in Hepatocellular Carcinoma

  6. the aim of this study was to analyze the effect of RECK gene rs 11788747 single nucleotide polymorphism (SNP) on hepatocellular carcinoma (HCC (zeige FAM126A Proteine)) susceptibility.

  7. Findings suggest that RECK transcript variants might have opposite roles in GBM biology and the ratio of their expression levels may be informative for the prognostic outcome of GBM patients.

  8. miR (zeige MLXIP Proteine)-21 has a role in upregulating PTEN, RECK and PDCD4 (zeige PDCD4 Proteine) in glioma

  9. RECK is a regulator of hMSC functions suggesting that modulation of RECK may improve the development of hMSC-based therapeutical approaches in regenerative medicine.

  10. MMP-9 (zeige MMP9 Proteine)/RECK imbalance in cervical smears is significantly associated with high-grade cervical diseases and infection by alpha-9 HPV and C. trachomatis.

Mouse (Murine) Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK) Interaktionspartner

  1. experiments indicate that Reck and Gpr124 are part of the cell surface protein complex that transduces Wnt7a- and Wnt7b-specific signals in mammalian CNS Epithelial Cells to promote angiogenesis and regulate the BBB.

  2. These findings demonstrate the importance of appropriate cell-cell interactions and ECM (zeige MMRN1 Proteine) maintenance for angiogenesis and the involvement of Reck as a critical regulator of these events.

  3. RECK-mediated beta1-Integrin regulation by TGF-beta1 (zeige TGFB1 Proteine) is critical for wound contraction in mice.

  4. MiR (zeige MLXIP Proteine)-21 modulated the osteoporosis by targeting RECK.

  5. microRNA-200b and microRNA-200c promote colorectal cancer cell proliferation via targeting RECK.

  6. The RECK silencing-EGFR (zeige EGFR Proteine)-HIF-2alpha (zeige EPAS1 Proteine) axis might be a key molecular mechanism to induce hyperplastic phenotype of epithelial cells.

  7. Angiotensin II suppresses RECK, but induces matrix metalloproteinases both in vivo and in vitro.

  8. therapeutic concentrations of ASA (zeige ARSA Proteine) inhibited IL-18 (zeige IL18 Proteine)-induced H(2)O(2) generation, MMP9 (zeige MMP9 Proteine) activation, RECK suppression, and CF migration.

  9. these data suggest that RECK is a novel transcriptional target of FXR (zeige NR1H4 Proteine) in mouse liver, and provide clues to better understanding the function of FXR (zeige NR1H4 Proteine) in liver.

  10. RECK expression in the mouse uterus is steroidally regulated and within endometrial epithelial and stromal cells, RECK regulates MMP9 (zeige MMP9 Proteine), but not MMP2 (zeige MMP2 Proteine) activity.

RECK Protein Überblick

Protein Überblick

The protein encoded by this gene is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane-anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase-9, a key enzyme involved in tumor invasion and metastasis.

Genbezeichner und Symbole assoziert mit RECK

  • reversion-inducing-cysteine-rich protein with kazal motifs (RECK)
  • reversion-inducing-cysteine-rich protein with kazal motifs (Reck)
  • mRECK Protein
  • St15 Protein

Bezeichner auf Proteinebene für RECK

membrane-anchored glycoprotein (metastasis and invasion) , reversion-inducing cysteine-rich protein with Kazal motifs , suppression of tumorigenicity 15 (reversion-inducing-cysteine-rich protein with kazal motifs) , suppression of tumorigenicity 5 (reversion-inducing-cysteine-rich protein with kazal motifs) , suppressor of tumorigenicity 15 protein , Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK) , membrane-anchored glycoprotein RECK , suppression of tumorigenicity 15 , reversion-inducing-cysteine-rich protein with Kasal motifs

GENE ID SPEZIES
8434 Homo sapiens
53614 Mus musculus
403477 Canis lupus familiaris
100519638 Sus scrofa
517232 Bos taurus
313488 Rattus norvegicus
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