Retinol Dehydrogenase 10 (All-Trans) Proteine (RDH10)

RDH10 encodes a retinol dehydrogenase, which converts all-trans-retinol to all-trans-retinal, with preference for NADP as a cofactor. Zusätzlich bieten wir Ihnen Retinol Dehydrogenase 10 (All-Trans) Antikörper (49) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
RDH10 157506 Q8IZV5
RDH10 98711 Q8VCH7
RDH10 353252 Q80ZF7
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 50 bis 55 Tage
$6,041.49
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Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
$4,244.78
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$405.71
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage
$785.40
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,924.17
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Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,924.17
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Hefe Xenopus tropicalis His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,924.17
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RDH10 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Rat (Rattus)

Weitere Proteine zu Retinol Dehydrogenase 10 (All-Trans) (RDH10) Interaktionspartnern

Human Retinol Dehydrogenase 10 (All-Trans) (RDH10) Interaktionspartner

  1. the bifunctional nature of retinoid oxidoreductase (zeige TXNRD1 Proteine) complex provides the RA-based signaling system with robustness by safeguarding appropriate RA concentration despite naturally occurring fluctuations in RDH10 and DHRS3 (zeige DHRS3 Proteine).

  2. Taken together, our findings demonstrate that RDH10 is essential during the early stages of facial morphogenesis for the formation of a functional nasal airway, and furthermore establish Rdh10 mutant mice as an important model system to study choanal atresia (CA) .

  3. Insulin (zeige INS Proteine) inhibits retinoic acid biosynthesis through inhibition of FoxO1 (zeige FOXO1 Proteine)-induced Rdh10 gene expression.

  4. Data indicate that retinaldehyde reductase (DHRS3 (zeige DHRS3 Proteine)) requires retinol dehydrogenase 10 (RDH10) for full enzymatic activity and, in turn, activates RDH10.

  5. all three proteins (RDH10, RALDH2 (zeige ALDH1A2 Proteine), and CRABP2 (zeige CRABP2 Proteine)) appeared to be required for ATRA production induced by activation of PPARgamma (zeige PPARG Proteine)

  6. Retinol dehydrogenase 10 but not retinol/sterol dehydrogenase(s) regulates the expression of retinoic acid-responsive genes in human transgenic skin raft culture.

  7. CYP4Z1 (zeige CYP4Z1 Proteine), KIR (zeige GEM Proteine) and RDH10 could play a role in non-small-cell lung cancer progression

  8. organization of the gene includes a unique transcriptional start site, a coding region with six translated exons and a 3' UTR containing at least two used polyadenylation sites.

  9. Forced over-expression of the RDH10 gene causes growth arrest of HepG2 cells and could be a possible curative strategy for hepatocellular carcinoma.

  10. dual physiological role for RDH10: in the biosynthesis of 11-cis (zeige CISH Proteine)-retinaldehyde for vision as well as the biosynthesis of all-trans-retinoic acid for differentiation and development

Mouse (Murine) Retinol Dehydrogenase 10 (All-Trans) (RDH10) Interaktionspartner

  1. Rdh10 null mutant mouse embryos exhibited dorsal pancreas agenesis and a hypoplastic ventral pancreas with retarded tubulogenesis and branching. Conditional disruption of Rdh10 from the endoderm caused increased mortality, reduced body weight, and lowered blood glucose levels after birth. Endodermal Rdh10 deficiency led to a smaller dorsal pancreas with a reduced density of early glucagon (zeige GCG Proteine)(+) and insulin (zeige INS Proteine)(+) cells.

  2. Taken together, our findings demonstrate that RDH10 is essential during the early stages of facial morphogenesis for the formation of a functional nasal airway, and furthermore establish Rdh10 mutant mice as an important model system to study choanal atresia (CA)

  3. RDH10 acts in cooperation with other RDH isoforms to produce the 11-cis (zeige CISH Proteine)-retinal chromophore needed for vision.

  4. Insulin (zeige INS Proteine) inhibits retinoic acid biosynthesis through inhibition of FoxO1 (zeige FOXO1 Proteine)-induced Rdh10 gene expression.

  5. all three proteins (RDH10, RALDH2 (zeige ALDH1A2 Proteine), and CRABP2 (zeige CRABP2 Proteine)) appeared to be required for ATRA production induced by activation of PPARgamma (zeige PPARG Proteine)

  6. Rdh10-/- embryos demonstrate that RA controls hindbrain but not early forebrain patterning, while studies on retinaldehyde-rescued Rdh10-/- embryos show that meningeal RA synthesis is unnecessary to stimulate forebrain cortical expansion.

  7. Retinol dehydrogenase 10 is indispensible for spermatogenesis in juvenile males.

  8. retinol dehydrogenase (zeige ADH7 Proteine) Rdh10 localizes to lipid droplets during acyl ester biosynthesis

  9. RDH10-mediated oxidation of retinol plays as important a role in the control and regulation of retinoic acid production during embryogenesis as does the subsequent RALDH-mediated reaction.

  10. identified a missense mutation in the Rdh10 gene (Rdh10(m366Asp) ) using an N-ethyl-N-nitrosourea-induced forward genetic screen that result in reduced RA levels and signaling during embryonic development

Retinol Dehydrogenase 10 (All-Trans) (RDH10) Protein Überblick

Protein Überblick

This gene encodes a retinol dehydrogenase, which converts all-trans-retinol to all-trans-retinal, with preference for NADP as a cofactor. Studies in mice suggest that this protein is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development.

Genbezeichner und Symbole assoziert mit RDH10

  • retinol dehydrogenase 10b (rdh10b)
  • retinol dehydrogenase 10 (MCYG_00691)
  • retinol dehydrogenase 10 (RDH10)
  • retinol dehydrogenase 10 (all-trans) (Rdh10)
  • retinol dehydrogenase 10 (Rdh10)
  • retinol dehydrogenase 10 (all-trans) (RDH10)
  • 3110069K09Rik Protein
  • 4921506A21Rik Protein
  • AI875664 Protein
  • AW549993 Protein
  • cb804 Protein
  • D1Ertd762e Protein
  • m366Asp Protein
  • rdh10 Protein
  • SDR16C4 Protein

Bezeichner auf Proteinebene für RDH10

retinol dehydrogenase 10 , retinol dehydrogenase 10-B , retinol dehydrogenase 10 (all-trans) , retinol dehydrogenase 10-like , short chain dehydrogenase/reductase family 16C, member 4

GENE ID SPEZIES
378722 Danio rerio
9223482 Arthroderma otae CBS 113480
100409203 Callithrix jacchus
157506 Homo sapiens
486998 Canis lupus familiaris
100127136 Sus scrofa
282852 Bos taurus
98711 Mus musculus
353252 Rattus norvegicus
420183 Gallus gallus
Ausgewählte Anbieter für Retinol Dehydrogenase 10 (All-Trans) Proteine (RDH10)
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