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RBBP5 encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. Zusätzlich bieten wir Ihnen Retinoblastoma Binding Protein 5 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 59 products:
Cow (Bovine) Polyclonal RBBP5 Primary Antibody für WB - ABIN404926
Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006
Non active site mutations in the MLL1 SET domain render the protein defective for H3K4 dimethylation by the MLL1 core complex, which is associated with a loss of the ability of MLL1 to interact with WRAD or with the RbBP5/Ash2L (zeige ASH2L Antikörper) heterodimer.
Data indicate that MLL1 methylates Ash2L (zeige ASH2L Antikörper) in the absence of histone H3 (zeige HIST3H3 Antikörper), but only when assembled within a complex with WDR5 (zeige WDR5 Antikörper) and RbBP5.
structural and biochemical analyses reveal a basic surface on Ash2L (zeige ASH2L Antikörper) as the RbBP5-binding interface, and this interface is crucial for both RbBP5 binding and MLL1 methyltransferase activity regulation
Results show that Depletion of CHD8 (zeige CHD8 Antikörper) enhances HOXA2 (zeige HOXA2 Antikörper) expression and a loss of the WDR5 (zeige WDR5 Antikörper)/Ash2L (zeige ASH2L Antikörper)/RbBP5 subcomplex.
analysis of menin's role as a tumor suppressor and binding sites of Rbbp5 and MLL1
a phosphorylation switch on RbBP5 stimulates WRAD complex formation and significantly increases KMT2 (lysine [K] methyltransferase 2 (zeige DNMT1 Antikörper)) enzyme methylation rates
Characterization of a novel WDR5 (zeige WDR5 Antikörper)-binding site that recruits RbBP5 through a conserved motif to enhance methylation of histone H3 (zeige HIST3H3 Antikörper) lysine 4 by mixed lineage leukemia protein-1.
This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
retinoblastoma binding protein 5
, retinoblastoma-binding protein 5-like
, SWD1, Set1c WD40 repeat protein, homolog
, retinoblastoma-binding protein 5
, retinoblastoma-binding protein RBQ-3