Retinal G Protein Coupled Receptor Proteine (RGR)

RGR encodes a putative retinal G-protein coupled receptor. Zusätzlich bieten wir Ihnen RGR Antikörper (54) und RGR Kits (3) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
RGR 5995 P47804
RGR 57811 Q9Z2B3
Ratte RGR RGR 306307  
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Showing 4 out of 4 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 50 bis 55 Tage
$6,041.49
Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
$4,244.78
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$405.71
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Wheat germ Human Unkonjugiert   2 μg Anmelden zum Anzeigen 11 bis 12 Tage
$491.43
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RGR Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine)

Weitere Proteine zu Retinal G Protein Coupled Receptor (RGR) Interaktionspartnern

Mouse (Murine) Retinal G Protein Coupled Receptor (RGR) Interaktionspartner

  1. structure of rhodopsin and opsin dimer in native membranes

  2. The role of Rgr using rgr-/- single and rdh5 (zeige RDH5 Proteine)-/-rgr-/- double knockout mice under a number of light conditions was studied; results suggest that RGR and RDH5 (zeige RDH5 Proteine) are likely to function in the retinoid cycle, although their role is not essential

  3. RGR-opsin mediates light-dependent translocation of all-trans-retinyl esters from a storage pool in lipid droplets to an "isomerase pool" in membranes of the endoplasmic reticulum.

Human Retinal G Protein Coupled Receptor (RGR) Interaktionspartner

  1. study to systemically analyze the potential role of variants of RGR in retinal diseases results of the suggested that the heterozygous truncation variants in RGR were less likely to be pathogenic

  2. conclude that the ability of hRgr to activate both Ral and Ras is responsible for its transformation-inducing phenotype and it could be an important contributor in the development of some T-cell malignancies

  3. It is likely that mutations in RGR, RBP3 (zeige E2F1 Proteine), and possibly RBP1 occur rarely in inherited retinal dystrophies.

  4. E150K opsin is partially colocalized with the cis/medial Golgi compartment but not with the trans-Golgi network; results are consistent with recessive pattern of inheritance; retinal degeneration results from deficient export of opsin from the Golgi

  5. These results indicate that after exon-skipping RGR splice isoform (RGR-d) is synthesized, the RGR-d epitope is released at the basal surface of the retinal pigment epithelium and deposited into Bruch's membrane in human eyes throughout adult life.

  6. RGR-opsin mediates light-dependent translocation of all-trans-retinyl esters from a storage pool in lipid droplets to an "isomerase pool" in membranes of the endoplasmic reticulum.

  7. the exon-skipping variant of RGR (RGR-d) is found in extracellular deposits;at the base of early-stage drusen mounds in the older donors and may precede the formation of these drusen

RGR Protein Überblick

Protein Überblick

This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms.

Genbezeichner und Symbole assoziert mit RGR

  • retinal G protein coupled receptor (RGR)
  • retinal G protein coupled receptor (Rgr)
  • retinal G protein coupled receptor L homeolog (rgr.L)
  • retinal G protein coupled receptor (rgr)
  • retinal G protein coupled receptor a (rgra)
  • MGC84794 Protein
  • rgr Protein
  • RP44 Protein
  • zgc:110660 Protein

Bezeichner auf Proteinebene für RGR

RGR-opsin , RPE retinal G-protein coupled receptor , RPE-retinal G protein-coupled receptor , RGR opsin , retinal g-protein receptor opsin , rgr opsin , retinal G protein coupled receptor , retinal G-protein coupled receptor

GENE ID SPEZIES
5995 Homo sapiens
57811 Mus musculus
280911 Bos taurus
306307 Rattus norvegicus
423619 Gallus gallus
444753 Xenopus laevis
450906 Pan troglodytes
489072 Canis lupus familiaris
548767 Xenopus (Silurana) tropicalis
550575 Danio rerio
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