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Ras and Rab Interactor 1 Proteine (RIN1)

Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Zusätzlich bieten wir Ihnen RIN1 Antikörper (45) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
RIN1 9610 Q13671
RIN1 225870 Q921Q7
RIN1 207119 P97680
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Showing 4 out of 5 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 66 Days
10.536,00 €
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 66 Days
10.536,00 €
Details
HOST_Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 7 bis 8 Tage
235,20 €
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
4.066,50 €
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RIN1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine)

Rat (Rattus)

Weitere Proteine zu Ras and Rab Interactor 1 (RIN1) Interaktionspartnern

Human Ras and Rab Interactor 1 (RIN1) Interaktionspartner

  1. Overexpression experiments in tandem with pull-down assays indicated that specific Ser291/292 phosphorylation of RIN1 favored binding to activated Ras

  2. analysis of a novel deregulated mechanism in chronic myeloid leukemia (zeige BCL11A Proteine) patients, indicating BIN1 (zeige BIN1 Proteine) and RIN1 as players in the maintenance of the abnormal RTK signaling in this hematological disease

  3. Findings suggest that RIN1 orchestrates RAB5 (zeige RAB5A Proteine) activation, ABL kinase activation and BIN1 (zeige BIN1 Proteine) recruitment to determine EGFR (zeige EGFR Proteine) fate.

  4. over-expression of RIN1 may play an important role in the progression of non-small cell lung cancer and RIN1 expression may offer a valuable marker for predicting the outcome of patients with NSCLC

  5. RIN1 plays an important role in gastric adenocarcinoma progression and that a high RIN1 expression predicts an unfavorable prognosis in gastric adenocarcinoma patients.

  6. RIN1 expression could be a potential prognostic predictor for the melanoma patients and provide a potential target therapy for melanoma treatment.

  7. RIN1 expression could be a potential prognostic predictor for bladder urothelial carcinoma (UC) patients.

  8. These data identify a novel PKD signaling pathway through RIN1 and Abl kinases that is involved in the regulation of actin remodeling and cell migration.

  9. BCR (zeige BCR Proteine)-ABL1 (zeige ABL1 Proteine) kinase activity is regulated by RIN1

  10. Plays an important role in both insulin receptor (zeige INSR Proteine) membrane trafficking and signaling.

Mouse (Murine) Ras and Rab Interactor 1 (RIN1) Interaktionspartner

  1. BCR (zeige BCR Proteine)-ABL1 (zeige ABL1 Proteine) kinase activity is regulated by RIN1

  2. These results provide insight into regulated expression of Rin1, define a promoter useful in telencephalic neuron studies, and describe a novel REST site variant directing expression to mature neurons.

  3. This study provided evidence that Rin1 normally functions as a negative regulator of fear learning and memory (Rin1-/- mice have enhanced fear conditioning and diminished fear extinction).

  4. Rin1 links histone ubiquitylation to gene silencing and X inactivation.

  5. RIN1 is an ABL tyrosine kinase activator and a regulator of epithelial-cell adhesion and migration.

  6. the EphA4 (zeige EPHA4 Proteine) receptor is required for synaptic plasticity in the amygdala, raising the possibility that an underlying mechanism of Rin1 function in amygdala is to down-regulate EphA4 (zeige EPHA4 Proteine) signaling by promoting its endocytosis.

RIN1 Protein Überblick

Protein Überblick

Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.

Genbezeichner und Symbole assoziert mit RIN1

  • Ras and Rab interactor 1 (RIN1)
  • Ras and Rab interactor 1 (Rin1)
  • RIN1 Protein

Bezeichner auf Proteinebene für RIN1

Ras and Rab interactor 1 , ras and Rab interactor 1-like , ras and Rab interactor 1 , ras inhibitor 1 , ras inhibitor JC99 , ras inhibitor RIN1 , ras interaction/interference protein 1 , ras inhibitor

GENE ID SPEZIES
611928 Canis lupus familiaris
714321 Macaca mulatta
100058267 Equus caballus
100395614 Callithrix jacchus
100437658 Pongo abelii
100482238 Ailuropoda melanoleuca
9610 Homo sapiens
225870 Mus musculus
207119 Rattus norvegicus
100520715 Sus scrofa
509295 Bos taurus
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