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RHOU encodes a member of the Rho family of GTPases. Zusätzlich bieten wir Ihnen RHOU Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 41 products:
Human Polyclonal RHOU Primary Antibody für ELISA - ABIN249477
Tao, Pennica, Xu, Kalejta, Levine: Wrch-1, a novel member of the Rho gene family that is regulated by Wnt-1. in Genes & development 2001
PAK4 (zeige PAK4 Antikörper) and RhoU cooperate to drive adhesion turnover and promote cell migration.
Data indicate that upregulated miR (zeige MLXIP Antikörper)-126 upon coxsackievirus B3 (CVB3) infection targets SPRED1 (zeige SPRED1 Antikörper), LRP6 (zeige LRP6 Antikörper), and WRCH1 genes, mediating cross-talk between ERK1/2 (zeige MAPK1/3 Antikörper) and Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) pathways, and thus promoting viral replication.
multiple upstream signals may converge on Wrch1 directly through its SH3 domain (zeige ITSN1 Antikörper)-binding properties
results indicate that NOTCH1 (zeige NOTCH1 Antikörper) mutation stimulates T-cell acute lymphoblastic leukaemia cell migration through RhoU upregulation that could contribute to the leukaemia cell dissemination
data suggest a unique regulatory mechanism by which RhoU interaction with SH3 adaptor proteins might serve to integrate growth factor receptor (zeige RYK Antikörper) signaling with RhoU activatio
A screen for Wrch-1 binding-partners identified the novel RhoGAP protein (zeige ARHGAP26 Antikörper), ARHGAP30 (zeige ARHGAP30 Antikörper), as a Wrch-1 interactor.
Studies revealed a requirement for serum-stimulated tyrosine phosphorylation of Wrch1 at residue Y254 within its C-terminal membrane targeting domain, mediated by the nonreceptor tyrosine kinase (zeige TXK Antikörper) Src (zeige SRC Antikörper).
Down regulation of WRCH1 by estradiol in breast cancer and altered expression of WRCH1 is associated with other cancers
G28K cDNA encodes a protein of 258 amino acids with homology to the cell division cycle 42/G25K protein; this gene is located at 1q42.11-q42.3; G28K was abundantly expressed in the stomach and the small intestine
These data suggest that Wrch-1 regulates cell migration by multiple mechanisms: on the one hand Wrch-1 controls focal adhesions by regulating myosin light chain and on the other hand Wrch-1 stimulates the activation of Akt (zeige AKT1 Antikörper) and JNK (zeige MAPK8 Antikörper).
Rhou activity maintains the epithelial architecture of the endoderm progenitors, and its downregulation accompanies the transition of the columnar epithelium in the embryonic foregut to a multilayered cell sheet during organ formation.
G28K was differentially expressed in the small intestines; interstitial cells of Cajal within the small intestine expressed mRNA for G28K; downregulated in the jejunum of W/W V mice.
Wrch-1 membrane association, subcellular localization, and biological activity are mediated by a novel membrane-targeting mechanism distinct from that of Cdc42 (zeige CDC42 Antikörper) and other isoprenylated Rho family GTPases
Wrch1 collaborates with FAK2 (zeige PTK2B Antikörper) and Src (zeige SRC Antikörper) in regulating cytoskeletal dynamics.
This gene encodes a member of the Rho family of GTPases. This protein can activate PAK1 and JNK1, and can induce filopodium formation and stress fiber dissolution. It may also mediate the effects of WNT1 signaling in the regulation of cell morphology, cytoskeletal organization, and cell proliferation. A non-coding transcript variant of this gene results from naturally occurring read-through transcription between this locus and the neighboring DUSP5P (dual specificity phosphatase 5 pseudogene) locus.
ras homolog gene family, member U
, CDC42-like GTPase 1
, GTP-binding protein SB128
, GTP-binding protein like 1
, Ryu GTPase
, ras-like gene family member U
, rho GTPase-like protein ARHU
, rho-related GTP-binding protein RhoU
, wnt-1 responsive Cdc42 homolog 1
, Ras-like protein member U
, Wnt1 responsive Cdc42 homolog