anti-Ras Homolog Gene Family, Member J (RHOJ) Antikörper

RHOJ encodes one of the many small GTP-binding proteins in the Rho family shown to be associated with focal adhesions in endothelial cells (PMID: 21148427, 22103495). Zusätzlich bieten wir Ihnen Ras Homolog Gene Family, Member J Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
RHOJ 57381 Q9H4E5
RHOJ 299145  
RHOJ 80837 Q9ER71
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Top anti-Ras Homolog Gene Family, Member J Antikörper auf antikoerper-online.de

Showing 10 out of 57 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-RHOJ Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>721_B cell lysate WB Suggested Anti-RHOJ <br /> Antibody Titration: 0.2-1 µg/mL <br /> Positive Control:.21_B cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Maus Unkonjugiert IF, WB Immunofluorescence of monoclonal antibody to RHOJ on HeLa cell (antibody concentration 60 µg/mL). RHOJ monoclonal antibody (M01), clone 1E4 Western Blot analysis of RHOJ expression in HepG2. 0.1 mg Anmelden zum Anzeigen 12 bis 16 Tage
454,76 €
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Human Kaninchen Unkonjugiert EIA, IHC (p), WB Formalin fixed, paraffin embedded Mouse heart tissue stained with RhoJ Antibody  followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RHOJ Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. Western blot analysis of RhoJ Antibody  in HepG2,MDA-MB231 cell line lysates (35ug/lane).This demonstrates the RHOJ antibody detected the RHOJ protein (arrow). 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB RHOJ Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded mouse heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RHOJ Antibody (Center) for immunohistochemistry.  Clinical relevance has not been evaluated. RHOJ Antibody (Center)  western blot analysis in HepG2,MDA-MB231 cell line lysates (35ug/lane).This demonstrates the RHOJ antibody detected the RHOJ protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
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Human Maus Unkonjugiert IF, ELISA, WB RHOJ monoclonal antibody (M01), clone 1E4 Western Blot analysis of RHOJ expression in HepG2 Immunofluorescence of monoclonal antibody to RHOJ on HeLa cell. [antibody concentration 60 ug/ml] 100 μg Anmelden zum Anzeigen 7 bis 8 Tage
369,60 €
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Human Maus Unkonjugiert IHC (p), WB 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
583,17 €
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Human Maus Unkonjugiert IF, IHC (p), WB 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
583,17 €
Details
Human Maus Unkonjugiert IF, IHC, WB Immunohistochemistry: RHOJ Antibody (1D7) [NBP2-45590] - Analysis of Human breast tissue. Immunohistochemistry: RHOJ Antibody (1D7) [NBP2-45590] - Analysis of Human liver tissue. 0.1 mL Anmelden zum Anzeigen 3 bis 6 Tage
341,00 €
Details
Human Kaninchen Unkonjugiert WB RHOJ antibody used at 1 ug/ml to detect target protein. 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
460,89 €
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RHOJ Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human
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Rat (Rattus)


Mouse (Murine)


Am meisten referenzierte anti-Ras Homolog Gene Family, Member J Antikörper

  1. Human Monoclonal RHOJ Primary Antibody für IF, ELISA - ABIN566105 : Fukushima, Okada, Kataoka, Hirashima, Yoshida, Mann, Gomi, Nishida, Nishikawa, Uemura: Sema3E-PlexinD1 signaling selectively suppresses disoriented angiogenesis in ischemic retinopathy in mice. in The Journal of clinical investigation 2011 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen Ras Homolog Gene Family, Member J Interaktionspartner

Human Ras Homolog Gene Family, Member J (RHOJ) Interaktionspartner

  1. Short-term treatment of nascent melanoma tumors with PAK inhibitors that block RhoJ signaling halts the growth of BRAF (zeige BRAF Antikörper) mutant melanoma tumors in vivo and induces apoptosis in melanoma cells in vitro via a BAD-dependent mechanism. As up to 50% of BRAF (zeige BRAF Antikörper) mutant human melanomas express high levels of RhoJ, these studies nominate the RhoJ-BAD signaling network as a therapeutic vulnerability for fledgling BRAF (zeige BRAF Antikörper) mutant human tumor

  2. These results identify amino acids within the N terminus and a loop region distal to the nucleotide binding pocket of TCL capable of allosterically regulating nucleotide exchange and thus influence membrane association of the protein.

  3. FMNL3 interacts with Cdc42 and RhoJ, two Rho family GTPases known to be required for lumen formation. FMNL3 and RhoJ are concentrated at the early apical surface, or AMIS, and regulate the formation of radiating actin cables from this site.

  4. RhoJ-knockout mice showed reduced tumour growth and diminished tumour vessel density, identifying a role for RhoJ in mediating tumour angiogenesis. Studies give insight into the molecular function of RhoJ in regulating cell motility.

  5. These results identify RhoJ blockade as a selective and effective therapeutic strategy for targeting tumor vasculature with minimal side effects.

  6. These observations identify RHOJ as a melanoma linchpin determinant that regulates both actin cytoskeletal dynamics and chemoresistance by activating PAK1 (zeige PAK1 Antikörper).

  7. Arhgef15 acts as an endothelial cell-specific GEF to mediate VEGF-induced Cdc42 activation and potentiate RhoJ inactivation, thereby promoting actin polymerization and cell motility.

  8. we identified RhoJ and its effector PAK1 (zeige PAK1 Antikörper), as key modulators of melanoma cell sensitivity to DNA damage

  9. Our study supports a novel role for the Rho family member RhoJ in ednothelial cell morphogenesis and in particular in lumen formation

  10. RhoJ is endothelial-expressed in vivo, activated by vascular endothelial growth factor, localizes to focal adhesions, regulates endothelial cell migration and tube formation, and modulates actomyosin contractility and focal adhesion numbers.

Mouse (Murine) Ras Homolog Gene Family, Member J (RHOJ) Interaktionspartner

  1. RhoJ-knockout mice showed reduced tumour growth and diminished tumour vessel density, identifying a role for RhoJ in mediating tumour angiogenesis. Studies give insight into the molecular function of RhoJ in regulating cell motility.

  2. These results identify RhoJ blockade as a selective and effective therapeutic strategy for targeting tumor vasculature with minimal side effects.

  3. RhoJ is endothelial-expressed in vivo, activated by vascular endothelial growth factor, localizes to focal adhesions, regulates endothelial cell migration and tube formation, and modulates actomyosin contractility and focal adhesion numbers.

  4. The results strongly suggest that TCL/TC10betaL regulates adipocyte differentiation by controlling mitotic clonal expansion and this regulatory effect is closely linked to C/EBPbeta (zeige CEBPB Antikörper) and C/EBPdelta (zeige CEBPD Antikörper) expression.

  5. TCL/TC10betaL has a crucial role in the early stage of adipocyte differentiation, is probably linked to the PPARgamma (zeige PPARG Antikörper) pathway, and up-regulates epression of genes associated with adipogenesis.

  6. Insulin (zeige INS Antikörper) induces phosphatidylinositol 3-phosphate formation through TC10 (zeige RHOQ Antikörper) activation.

Ras Homolog Gene Family, Member J (RHOJ) Antigen-Profil

Protein Überblick

This gene encodes one of the many small GTP-binding proteins in the Rho family shown to be associated with focal adhesions in endothelial cells (PMID: 21148427, 22103495). The encoded protein is activated by vascular endothelial growth factor and may regulate angiogenesis.

Genbezeichner und Symbole assoziert mit RHOJ

  • ras homolog gene family, member J (RHOJ) Antikörper
  • ras homolog gene family, member J (rhoj) Antikörper
  • ras homolog family member J (RHOJ) Antikörper
  • ras homolog family member J (rhoj) Antikörper
  • ras homolog gene family, member J (LOC100350942) Antikörper
  • ras homolog family member J (Rhoj) Antikörper
  • ras homolog gene family, member J (Rhoj) Antikörper
  • 1110005O19Rik Antikörper
  • Arhj Antikörper
  • AW210585 Antikörper
  • MGC83410 Antikörper
  • RASL7B Antikörper
  • RHOJ Antikörper
  • si:dkey-100h21.1 Antikörper
  • TC10B Antikörper
  • TC10L Antikörper
  • TCL Antikörper

Bezeichner auf Proteinebene für RHOJ

ras homolog gene family, member J , TC10-like Rho GTPase , rho-related GTP-binding protein RhoJ , RAS-like, family 7, member B , ras-like protein family member 7B , tc10-like GTP-binding protein , tc10-like GTP-binding protein TCL

GENE ID SPEZIES
423513 Gallus gallus
444554 Xenopus laevis
452960 Pan troglodytes
540619 Bos taurus
556371 Danio rerio
612985 Canis lupus familiaris
705603 Macaca mulatta
100125013 Xenopus (Silurana) tropicalis
100155474 Sus scrofa
100350942 Oryctolagus cuniculus
57381 Homo sapiens
299145 Rattus norvegicus
80837 Mus musculus
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